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Robin Shandas

TitleDistinguished Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-PEDS
Phone303/724-4196
    Other Positions
    TitleProfessor
    InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
    DepartmentCEDC-Bioengineering


    Collapse Research 
    Collapse research activities and funding
    R01HL114753     (SHANDAS, ROBIN)Aug 15, 2012 - Jun 30, 2019
    NIH
    Functional and Biological Phenotyping of Pediatric PH
    Role: Principal Investigator
    R21EB004481     (SHANDAS, ROBIN)Aug 15, 2005 - Jul 31, 2008
    NIH
    Development of SMP's for Cardiovascular Use
    Role: Principal Investigator
    K24HL081506     (SHANDAS, ROBIN)Jul 1, 2005 - Jun 30, 2019
    NIH
    Comprehensive Clinical Assessment of Pediatric PHT
    Role: Principal Investigator
    R21HL079868     (SHANDAS, ROBIN)Jul 14, 2004 - Jun 30, 2007
    NIH
    Real Time Multi-Component Blood FLow Velocimetry
    Role: Principal Investigator
    T32HL072738     (SHANDAS, ROBIN)Apr 1, 2003 - Aug 31, 2026
    NIH
    Cardiovascular Biomechanics and Imaging
    Role: Principal Investigator
    R01HL067393     (SHANDAS, ROBIN)Jul 1, 2001 - May 31, 2007
    NIH
    Noninvasive Assessment of Primary Pulmonary Hypertension
    Role: Principal Investigator
    R03HL055243     (SHANDAS, ROBIN)Sep 15, 1996 - Aug 31, 1999
    NIH
    EFFECTIVE FLOW AREAS OF BILEAFLET MECHANICAL VALVES
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rocker AJ, Cavasin M, Johnson NR, Shandas R, Park D. Sulfonated Thermoresponsive Injectable Gel for Sequential Release of Therapeutic Proteins to Protect Cardiac Function after Myocardial Infarction. ACS Biomater Sci Eng. 2022 09 12; 8(9):3883-3898. PMID: 35950643.
      View in: PubMed
    2. Rocker AJ, Lee DJ, Shandas R, Park D. Injectable Polymeric Delivery System for Spatiotemporal and Sequential Release of Therapeutic Proteins To Promote Therapeutic Angiogenesis and Reduce Inflammation. ACS Biomater Sci Eng. 2020 02 10; 6(2):1217-1227. PMID: 33464833.
      View in: PubMed
    3. Pe?a B, Maldonado M, Bonham AJ, Aguado BA, Dominguez-Alfaro A, Laughter M, Rowland TJ, Bardill J, Farnsworth NL, Alegret Ramon N, Taylor MRG, Anseth KS, Prato M, Shandas R, McKinsey TA, Park D, Mestroni L. Gold Nanoparticle-Functionalized Reverse Thermal Gel for Tissue Engineering Applications. ACS Appl Mater Interfaces. 2019 May 22; 11(20):18671-18680. PMID: 31021594.
      View in: PubMed
    4. Kheyfets VO, Truong U, Ivy D, Shandas R. Structural and Biomechanical Adaptations of Right Ventricular Remodeling-In Pulmonary Arterial Hypertension-Reduces Left Ventricular Rotation During Contraction: A Computational Study. J Biomech Eng. 2019 May 01; 141(5). PMID: 30714069.
      View in: PubMed
    5. Govindarajan T, Shandas R. Microgrooves Encourage Endothelial Cell Adhesion and Organization on Shape-Memory Polymer Surfaces. ACS Appl Bio Mater. 2019 May 20; 2(5):1897-1906. PMID: 35030679.
      View in: PubMed
    6. Lee DJ, Cavasin MA, Rocker AJ, Soranno DE, Meng X, Shandas R, Park D. An injectable sulfonated reversible thermal gel for therapeutic angiogenesis to protect cardiac function after a myocardial infarction. J Biol Eng. 2019; 13:6. PMID: 30675179.
      View in: PubMed
    7. Lee DJ, Rocker AJ, Bardill JR, Shandas R, Park D. A sulfonated reversible thermal gel for the spatiotemporal control of VEGF delivery to promote therapeutic angiogenesis. J Biomed Mater Res A. 2018 12; 106(12):3053-3064. PMID: 30295997.
      View in: PubMed
    8. DeBoer EM, Wagner J, Kroehl ME, Albietz J, Shandas R, Deterding RR, Rustici MJ. Three-Dimensional Printed Pediatric Airway Model Improves Novice Learners' Flexible Bronchoscopy Skills With Minimal Direct Teaching From Faculty. Simul Healthc. 2018 Aug; 13(4):284-288. PMID: 29381588.
      View in: PubMed
    9. Dufva MJ, Truong U, Tiwari P, Ivy DD, Shandas R, Kheyfets VO. Left ventricular torsion rate and the relation to right ventricular function in pediatric pulmonary arterial hypertension. Pulm Circ. 2018 Jul-Sep; 8(3):2045894018791352. PMID: 30003835.
      View in: PubMed
    10. Gates PE, Gurung A, Mazzaro L, Aizawa K, Elyas S, Strain WD, Shore AC, Shandas R. Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry. Ultrasound Med Biol. 2018 07; 44(7):1392-1401. PMID: 29678322.
      View in: PubMed
    11. Govindarajan T, Shandas R. Shape Memory Polymers Containing Higher Acrylate Content Display Increased Endothelial Cell Attachment. Polymers (Basel). 2017 Nov; 9(11). PMID: 29707382.
      View in: PubMed
    12. Pe?a B, Bosi S, Aguado BA, Borin D, Farnsworth NL, Dobrinskikh E, Rowland TJ, Martinelli V, Jeong M, Taylor MRG, Long CS, Shandas R, Sbaizero O, Prato M, Anseth KS, Park D, Mestroni L. Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel Promotes Cardiomyocytes Survival and Maturation. ACS Appl Mater Interfaces. 2017 Sep 20; 9(37):31645-31656. PMID: 28895403.
      View in: PubMed
    13. Kheyfets VO, Sucharov CC, Truong U, Dunning J, Hunter K, Ivy D, Miyamoto S, Shandas R. Circulating miRNAs in Pediatric Pulmonary Hypertension Show Promise as Biomarkers of Vascular Function. Oxid Med Cell Longev. 2017; 2017:4957147. PMID: 28819545.
      View in: PubMed
    14. Gurung A, Gates PE, Mazzaro L, Fulford J, Zhang F, Barker AJ, Hertzberg J, Aizawa K, Strain WD, Elyas S, Shore AC, Shandas R. Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging. Ultrasound Med Biol. 2017 08; 43(8):1618-1627. PMID: 28501327.
      View in: PubMed
    15. Sch?fer M, Ivy DD, Barker AJ, Kheyfets V, Shandas R, Abman SH, Hunter KS, Truong U. Characterization of CMR-derived haemodynamic data in children with pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2017 Apr 01; 18(4):424-431. PMID: 27444679.
      View in: PubMed
    16. Madhavan K, Frid MG, Hunter K, Shandas R, Stenmark KR, Park D. Development of an electrospun biomimetic polyurea scaffold suitable for vascular grafting. J Biomed Mater Res B Appl Biomater. 2018 Jan; 106(1):278-290. PMID: 28130878.
      View in: PubMed
    17. Kheyfets VO, Dunning J, Truong U, Ivy D, Hunter K, Shandas R. A Zero-Dimensional Model and Protocol for Simulating Patient-Specific Pulmonary Hemodynamics From Limited Clinical Data. J Biomech Eng. 2016 12 01; 138(12). PMID: 27684888.
      View in: PubMed
    18. Humphries SM, Hunter KS, Shandas R, Deterding RR, DeBoer EM. Erratum to: Analysis of pediatric airway morphology using statistical shape modeling. Med Biol Eng Comput. 2016 06; 54(6):913. PMID: 26815534.
      View in: PubMed
    19. Kheyfets VO, Schafer M, Podgorski CA, Schroeder JD, Browning J, Hertzberg J, Buckner JK, Hunter KS, Shandas R, Fenster BE. 4D magnetic resonance flow imaging for estimating pulmonary vascular resistance in pulmonary hypertension. J Magn Reson Imaging. 2016 10; 44(4):914-22. PMID: 27173445.
      View in: PubMed
    20. Pe?a B, Martinelli V, Jeong M, Bosi S, Lapasin R, Taylor MR, Long CS, Shandas R, Park D, Mestroni L. Biomimetic Polymers for Cardiac Tissue Engineering. Biomacromolecules. 2016 05 09; 17(5):1593-601. PMID: 27073119.
      View in: PubMed
    21. Sch?fer M, Browning J, Schroeder JD, Shandas R, Kheyfets VO, Buckner JK, Hunter KS, Hertzberg JR, Fenster BE. Vorticity is a marker of diastolic ventricular interdependency in pulmonary hypertension. Pulm Circ. 2016 Mar; 6(1):46-54. PMID: 27162613.
      View in: PubMed
    22. Sch?fer M, Kheyfets VO, Schroeder JD, Dunning J, Shandas R, Buckner JK, Browning J, Hertzberg J, Hunter KS, Fenster BE. Main pulmonary arterial wall shear stress correlates with invasive hemodynamics and stiffness in pulmonary hypertension. Pulm Circ. 2016 Mar; 6(1):37-45. PMID: 27076906.
      View in: PubMed
    23. Humphries SM, Hunter KS, Shandas R, Deterding RR, DeBoer EM. Analysis of pediatric airway morphology using statistical shape modeling. Med Biol Eng Comput. 2016 Jun; 54(6):899-911. PMID: 26718559.
      View in: PubMed
    24. Kheyfets VO, Dunning J, Truong U, Ivy DD, Hunter KA, Shandas R. Assessment of N-terminal prohormone B-type natriuretic peptide as a measure of vascular and ventricular function in pediatric pulmonary arterial hypertension. Pulm Circ. 2015 Dec; 5(4):658-66. PMID: 26697173.
      View in: PubMed
    25. Truong U, Patel S, Kheyfets V, Dunning J, Fonseca B, Barker AJ, Ivy D, Shandas R, Hunter K. Non-invasive determination by cardiovascular magnetic resonance of right ventricular-vascular coupling in children and adolescents with pulmonary hypertension. J Cardiovasc Magn Reson. 2015 Sep 16; 17:81. PMID: 26376972.
      View in: PubMed
    26. Pe?a B, Shandas R, Park D. A heparin-mimicking reverse thermal gel for controlled delivery of positively charged proteins. J Biomed Mater Res A. 2015 Jun; 103(6):2102-8. PMID: 25294242.
      View in: PubMed
    27. Wagner JL, Shandas R, Lanning CJ. Extubation force depends upon angle of force application and fixation technique: a study of 7 methods. BMC Anesthesiol. 2014; 14:74. PMID: 25214815.
      View in: PubMed
    28. Hunter KS, Fjield T, Heitzmann H, Shandas R, Kahook MY. Characterization of micro-invasive trabecular bypass stents by ex vivo perfusion and computational flow modeling. Clin Ophthalmol. 2014; 8:499-506. PMID: 24648713.
      View in: PubMed
    29. Yunker BE, Dodd GD, Chen SJ, Chang S, Lanning CJ, Scherzinger AL, Shandas R, Feng Y, Hunter KS. The design and fabrication of two portal vein flow phantoms by different methods. Med Phys. 2014 Feb; 41(2):023701. PMID: 24506653.
      View in: PubMed
    30. Zimkowski MM, Rentschler ME, Schoen JA, Mandava N, Shandas R. Biocompatibility and tissue integration of a novel shape memory surgical mesh for ventral hernia: in vivo animal studies. J Biomed Mater Res B Appl Biomater. 2014 Jul; 102(5):1093-100. PMID: 24327401.
      View in: PubMed
    31. Su Z, Tan W, Shandas R, Hunter KS. Influence of distal resistance and proximal stiffness on hemodynamics and RV afterload in progression and treatments of pulmonary hypertension: a computational study with validation using animal models. Comput Math Methods Med. 2013; 2013:618326. PMID: 24367392.
      View in: PubMed
    32. Yan F, Li X, Jiang C, Jin Q, Zhang Z, Shandas R, Wu J, Liu X, Zheng H. A novel microfluidic chip for assessing dynamic adhesion behavior of cell-targeting microbubbles. Ultrasound Med Biol. 2014 Jan; 40(1):148-57. PMID: 24210864.
      View in: PubMed
    33. Milgroom A, Intrator M, Madhavan K, Mazzaro L, Shandas R, Liu B, Park D. Mesoporous silica nanoparticles as a breast-cancer targeting ultrasound contrast agent. Colloids Surf B Biointerfaces. 2014 Apr 01; 116:652-7. PMID: 24269054.
      View in: PubMed
    34. Aurand ER, Wagner JL, Shandas R, Bjugstad KB. Hydrogel formulation determines cell fate of fetal and adult neural progenitor cells. Stem Cell Res. 2014 Jan; 12(1):11-23. PMID: 24141109.
      View in: PubMed
    35. Jin Q, Wang Z, Yan F, Deng Z, Ni F, Wu J, Shandas R, Liu X, Zheng H. A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. PLoS One. 2013; 8(9):e76544. PMID: 24086748.
      View in: PubMed
    36. Truong U, Fonseca B, Dunning J, Burgett S, Lanning C, Ivy DD, Shandas R, Hunter K, Barker AJ. Wall shear stress measured by phase contrast cardiovascular magnetic resonance in children and adolescents with pulmonary arterial hypertension. J Cardiovasc Magn Reson. 2013 Sep 13; 15:81. PMID: 24034144.
      View in: PubMed
    37. Yunker BE, Cordes D, Scherzinger AL, Dodd GD, Shandas R, Feng Y, Hunter KS. An investigation of industrial molding compounds for use in 3D ultrasound, MRI, and CT imaging phantoms. Med Phys. 2013 May; 40(5):052905. PMID: 23635298.
      View in: PubMed
    38. Zimkowski MM, Rentschler ME, Schoen J, Rech BA, Mandava N, Shandas R. Integrating a novel shape memory polymer into surgical meshes decreases placement time in laparoscopic surgery: an in vitro and acute in vivo study. J Biomed Mater Res A. 2013 Sep; 101(9):2613-20. PMID: 23412974.
      View in: PubMed
    39. Yan F, Li L, Deng Z, Jin Q, Chen J, Yang W, Yeh CK, Wu J, Shandas R, Liu X, Zheng H. Paclitaxel-liposome-microbubble complexes as ultrasound-triggered therapeutic drug delivery carriers. J Control Release. 2013 Mar 28; 166(3):246-55. PMID: 23306023.
      View in: PubMed
    40. Scott D, Tan Y, Shandas R, Stenmark KR, Tan W. High pulsatility flow stimulates smooth muscle cell hypertrophy and contractile protein expression. Am J Physiol Lung Cell Mol Physiol. 2013 Jan 01; 304(1):L70-81. PMID: 23087017.
      View in: PubMed
    41. Scott-Drechsel D, Su Z, Hunter K, Li M, Shandas R, Tan W. A new flow co-culture system for studying mechanobiology effects of pulse flow waves. Cytotechnology. 2012 Dec; 64(6):649-66. PMID: 22526489.
      View in: PubMed
    42. Nair DP, Cramer NB, McBride MK, Gaipa JC, Shandas R, Bowman CN. Enhanced Two-Stage Reactive Polymer Network Forming Systems. Polymer (Guildf). 2012 May 25; 53(12):2429-2434. PMID: 22798700.
      View in: PubMed
    43. Yan F, Li X, Jin Q, Chen J, Shandas R, Wu J, Li L, Ling T, Yang W, Chen Y, Liu X, Zheng H. Ultrasonic imaging of endothelial CD81 expression using CD81-targeted contrast agents in in vitro and in vivo studies. Ultrasound Med Biol. 2012 Apr; 38(4):670-80. PMID: 22341598.
      View in: PubMed
    44. Olson JL, Shandas R, Erlanger M. Development of a minimally invasive, injectable, shape memory suture and delivery system. Ann Biomed Eng. 2012 Jul; 40(7):1520-9. PMID: 22258886.
      View in: PubMed
    45. Tian L, Lammers SR, Kao PH, Albietz JA, Stenmark KR, Qi HJ, Shandas R, Hunter KS. Impact of residual stretch and remodeling on collagen engagement in healthy and pulmonary hypertensive calf pulmonary arteries at physiological pressures. Ann Biomed Eng. 2012 Jul; 40(7):1419-33. PMID: 22237861.
      View in: PubMed
    46. Lammers S, Scott D, Hunter K, Tan W, Shandas R, Stenmark KR. Mechanics and function of the pulmonary vasculature: implications for pulmonary vascular disease and right ventricular function. Compr Physiol. 2012 Jan; 2(1):295-319. PMID: 23728987.
      View in: PubMed
    47. Lammers S, Scott D, Hunter K, Tan W, Shandas R, Stenmark KR. Mechanics and Function of the Pulmonary Vasculature: Implications for Pulmonary Vascular Disease and Right Ventricular Function. Compr Physiol. 2012 Jan 01; 2(1):295-319. PMID: 23487595.
      View in: PubMed
    48. Su Z, Hunter KS, Shandas R. Impact of pulmonary vascular stiffness and vasodilator treatment in pediatric pulmonary hypertension: 21 patient-specific fluid-structure interaction studies. Comput Methods Programs Biomed. 2012 Nov; 108(2):617-28. PMID: 21975085.
      View in: PubMed
    49. Tian L, Lammers SR, Kao PH, Reusser M, Stenmark KR, Hunter KS, Qi HJ, Shandas R. Linked opening angle and histological and mechanical aspects of the proximal pulmonary arteries of healthy and pulmonary hypertensive rats and calves. Am J Physiol Heart Circ Physiol. 2011 Nov; 301(5):H1810-8. PMID: 21856906.
      View in: PubMed
    50. Hunter KS, Lammers SR, Shandas R. Pulmonary vascular stiffness: measurement, modeling, and implications in normal and hypertensive pulmonary circulations. Compr Physiol. 2011 Jul; 1(3):1413-35. PMID: 23733649.
      View in: PubMed
    51. Niu L, Qian M, Yan L, Yu W, Jiang B, Jin Q, Wang Y, Shandas R, Liu X, Zheng H. Real-time texture analysis for identifying optimum microbubble concentration in 2-D ultrasonic particle image velocimetry. Ultrasound Med Biol. 2011 Aug; 37(8):1280-91. PMID: 21684062.
      View in: PubMed
    52. Kao PH, Lammers SR, Tian L, Hunter K, Stenmark KR, Shandas R, Qi HJ. A microstructurally driven model for pulmonary artery tissue. J Biomech Eng. 2011 May; 133(5):051002. PMID: 21599093.
      View in: PubMed
    53. Zhang F, Lanning C, Mazzaro L, Barker AJ, Gates PE, Strain WD, Fulford J, Gosling OE, Shore AC, Bellenger NG, Rech B, Chen J, Chen J, Shandas R. In vitro and preliminary in vivo validation of echo particle image velocimetry in carotid vascular imaging. Ultrasound Med Biol. 2011 Mar; 37(3):450-64. PMID: 21316562.
      View in: PubMed
    54. Hunter KS, Feinstein JA, Ivy DD, Shandas R. Computational Simulation of the Pulmonary Arteries and its Role in the Study of Pediatric Pulmonary Hypertension. Prog Pediatr Cardiol. 2010 Dec 01; 30(1-2):63-69. PMID: 21499523.
      View in: PubMed
    55. Lindley EM, Jaafar S, Noshchenko A, Baldini T, Nair DP, Shandas R, Burger EL, Patel VV. Nucleus replacement device failure: a case report and biomechanical study. Spine (Phila Pa 1976). 2010 Oct 15; 35(22):E1241-7. PMID: 20881660.
      View in: PubMed
    56. Nair DP, Cramer NB, Scott TF, Bowman CN, Shandas R. Photopolymerized Thiol-Ene Systems as Shape Memory Polymers. Polymer (Guildf). 2010 Sep 03; 51(19):4383-4389. PMID: 21072253.
      View in: PubMed
    57. Tian L, Hunter KS, Kirby KS, Ivy DD, Shandas R. Measurement uncertainty in pulmonary vascular input impedance and characteristic impedance estimated from pulsed-wave Doppler ultrasound and pressure: clinical studies on 57 pediatric patients. Physiol Meas. 2010 Jun; 31(6):729-48. PMID: 20410558.
      View in: PubMed
    58. Kao PH, Lammers SR, Hunter K, Stenmark KR, Shandas R, Qi HJ. Constitutive Modeling of Anisotropic Finite-Deformation Hyperelastic Behaviors of Soft Materials Reinforced by Tortuous Fibers. Int J Struct Changes Sol. 2010 Apr; 2(1):19-29. PMID: 21822502.
      View in: PubMed
    59. Hunter KS, Albietz JA, Lee PF, Lanning CJ, Lammers SR, Hofmeister SH, Kao PH, Qi HJ, Stenmark KR, Shandas R. In vivo measurement of proximal pulmonary artery elastic modulus in the neonatal calf model of pulmonary hypertension: development and ex vivo validation. J Appl Physiol (1985). 2010 Apr; 108(4):968-75. PMID: 20093662.
      View in: PubMed
    60. Barker AJ, Lanning C, Shandas R. Quantification of hemodynamic wall shear stress in patients with bicuspid aortic valve using phase-contrast MRI. Ann Biomed Eng. 2010 Mar; 38(3):788-800. PMID: 19953319.
      View in: PubMed
    61. Chen J, Hunter KS, Shandas R. Wave scattering from encapsulated microbubbles subject to high-frequency ultrasound: contribution of higher-order scattering modes. J Acoust Soc Am. 2009 Oct; 126(4):1766-75. PMID: 19813791.
      View in: PubMed
    62. Liu J, Oakley C, Shandas R. Capacitive micromachined ultrasonic transducers using commercial multi-user MUMPs process: capability and limitations. Ultrasonics. 2009 Dec; 49(8):765-73. PMID: 19640557.
      View in: PubMed
    63. Lacour-Gayet FG, Lanning CJ, Stoica S, Wang R, Rech BA, Goldberg S, Shandas R. An artificial right ventricle for failing fontan: in vitro and computational study. Ann Thorac Surg. 2009 Jul; 88(1):170-6. PMID: 19559219.
      View in: PubMed
    64. Li M, Stenmark KR, Shandas R, Tan W. Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. J Vasc Res. 2009; 46(6):561-71. PMID: 19571576.
      View in: PubMed
    65. Li M, Scott DE, Shandas R, Stenmark KR, Tan W. High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells. Ann Biomed Eng. 2009 Jun; 37(6):1082-92. PMID: 19340571.
      View in: PubMed
    66. Yakacki CM, Shandas R, Safranski D, Ortega AM, Sassaman K, Gall K. Strong, Tailored, Biocompatible Shape-Memory Polymer Networks. Adv Funct Mater. 2008 Aug 22; 18(16):2428-2435. PMID: 19633727.
      View in: PubMed
    67. Lammers SR, Kao PH, Qi HJ, Hunter K, Lanning C, Albietz J, Hofmeister S, Mecham R, Stenmark KR, Shandas R. Changes in the structure-function relationship of elastin and its impact on the proximal pulmonary arterial mechanics of hypertensive calves. Am J Physiol Heart Circ Physiol. 2008 Oct; 295(4):H1451-9. PMID: 18660454.
      View in: PubMed
    68. Hunter KS, Gross JK, Lanning CJ, Kirby KS, Dyer KL, Ivy DD, Shandas R. Noninvasive methods for determining pulmonary vascular function in children with pulmonary arterial hypertension: application of a mechanical oscillator model. Congenit Heart Dis. 2008 Mar-Apr; 3(2):106-16. PMID: 18380759.
      View in: PubMed
    69. Liu L, Zheng H, Williams L, Zhang F, Wang R, Hertzberg J, Shandas R. Development of a custom-designed echo particle image velocimetry system for multi-component hemodynamic measurements: system characterization and initial experimental results. Phys Med Biol. 2008 Mar 07; 53(5):1397-412. PMID: 18296769.
      View in: PubMed
    70. Hunter KS, Lee PF, Lanning CJ, Ivy DD, Kirby KS, Claussen LR, Chan KC, Shandas R. Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension. Am Heart J. 2008 Jan; 155(1):166-74. PMID: 18082509.
      View in: PubMed
    71. Zhang Y, Dunn ML, Hunter KS, Lanning C, Ivy DD, Claussen L, Chen SJ, Shandas R. Application of a microstructural constitutive model of the pulmonary artery to patient-specific studies: validation and effect of orthotropy. J Biomech Eng. 2007 Apr; 129(2):193-201. PMID: 17408324.
      View in: PubMed
    72. Yakacki CM, Shandas R, Lanning C, Rech B, Eckstein A, Gall K. Unconstrained recovery characterization of shape-memory polymer networks for cardiovascular applications. Biomaterials. 2007 May; 28(14):2255-63. PMID: 17296222.
      View in: PubMed
    73. Wang R, Lacour-Gayet FG, Lanning CJ, Rech BA, Kilfoil PJ, Hertzberg J, Shandas R. Initial experience with the development and numerical and in vitro studies of a novel low-pressure artificial right ventricle for pediatric Fontan patients. ASAIO J. 2006 Nov-Dec; 52(6):682-92. PMID: 17117059.
      View in: PubMed
    74. Hunter KS, Lanning CJ, Chen SY, Zhang Y, Garg R, Ivy DD, Shandas R. Simulations of congenital septal defect closure and reactivity testing in patient-specific models of the pediatric pulmonary vasculature: A 3D numerical study with fluid-structure interaction. J Biomech Eng. 2006 Aug; 128(4):564-72. PMID: 16813447.
      View in: PubMed
    75. Dyer K, Lanning C, Das B, Lee PF, Ivy DD, Valdes-Cruz L, Shandas R. Noninvasive Doppler tissue measurement of pulmonary artery compliance in children with pulmonary hypertension. J Am Soc Echocardiogr. 2006 Apr; 19(4):403-12. PMID: 16581479.
      View in: PubMed
    76. Zheng H, Barker A, Shandas R. Predicting backscatter characteristics from micron- and submicron-scale ultrasound contrast agents using a size-integration technique. IEEE Trans Ultrason Ferroelectr Freq Control. 2006 Mar; 53(3):639-44. PMID: 16555773.
      View in: PubMed
    77. Orlando W, Shandas R, DeGroff C. Efficiency differences in computational simulations of the total cavo-pulmonary circulation with and without compliant vessel walls. Comput Methods Programs Biomed. 2006 Mar; 81(3):220-7. PMID: 16455152.
      View in: PubMed
    78. Zheng H, Mukdadi O, Shandas R. Theoretical predictions of harmonic generation from submicron ultrasound contrast agents for nonlinear biomedical ultrasound imaging. Phys Med Biol. 2006 Feb 07; 51(3):557-73. PMID: 16424581.
      View in: PubMed
    79. Dyer KL, Pauliks LB, Das B, Shandas R, Ivy D, Shaffer EM, Valdes-Cruz LM. Use of myocardial performance index in pediatric patients with idiopathic pulmonary arterial hypertension. J Am Soc Echocardiogr. 2006 Jan; 19(1):21-7. PMID: 16423665.
      View in: PubMed
    80. Zhang Y, Dunn ML, Drexler ES, McCowan CN, Slifka AJ, Ivy DD, Shandas R. A microstructural hyperelastic model of pulmonary arteries under normo- and hypertensive conditions. Ann Biomed Eng. 2005 Aug; 33(8):1042-52. PMID: 16133913.
      View in: PubMed
    81. Gall K, Yakacki CM, Liu Y, Shandas R, Willett N, Anseth KS. Thermomechanics of the shape memory effect in polymers for biomedical applications. J Biomed Mater Res A. 2005 Jun 01; 73(3):339-48. PMID: 15806564.
      View in: PubMed
    82. Mazzaro L, Almasi SJ, Shandas R, Seals DR, Gates PE. Aortic input impedance increases with age in healthy men and women. Hypertension. 2005 Jun; 45(6):1101-6. PMID: 15867143.
      View in: PubMed
    83. DeGroff C, Birnbaum B, Shandas R, Orlando W, Hertzberg J. Computational simulations of the total cavo-pulmonary connection: insights in optimizing numerical solutions. Med Eng Phys. 2005 Mar; 27(2):135-46. PMID: 15642509.
      View in: PubMed
    84. Zheng H, Mukdadi O, Kim H, Hertzberg JR, Shandas R. Advantages in using multifrequency excitation of contrast microbubbles for enhancing echo particle image velocimetry techniques: initial numerical studies using rectangular and triangular waves. Ultrasound Med Biol. 2005 Jan; 31(1):99-108. PMID: 15653236.
      View in: PubMed
    85. Weinberg CE, Hertzberg JR, Ivy DD, Kirby KS, Chan KC, Valdes-Cruz L, Shandas R. Extraction of pulmonary vascular compliance, pulmonary vascular resistance, and right ventricular work from single-pressure and Doppler flow measurements in children with pulmonary hypertension: a new method for evaluating reactivity: in vitro and clinical studies. Circulation. 2004 Oct 26; 110(17):2609-17. PMID: 15492299.
      View in: PubMed
    86. Kim HB, Hertzberg J, Lanning C, Shandas R. Noninvasive measurement of steady and pulsating velocity profiles and shear rates in arteries using echo PIV: in vitro validation studies. Ann Biomed Eng. 2004 Aug; 32(8):1067-76. PMID: 15446503.
      View in: PubMed
    87. Mukdadi OM, Kim HB, Hertzberg J, Shandas R. Numerical modeling of microbubble backscatter to optimize ultrasound particle image velocimetry imaging: initial studies. Ultrasonics. 2004 Aug; 42(10):1111-21. PMID: 15234173.
      View in: PubMed
    88. Cooke J, Hertzberg J, Boardman M, Shandas R. Characterizing vortex ring behavior during ventricular filling with Doppler echocardiography: an in vitro study. Ann Biomed Eng. 2004 Feb; 32(2):245-56. PMID: 15008372.
      View in: PubMed
    89. Wright JE, Drexler ES, Slifka AJ, McCowan CN, Ivy DD, Shandas R. Stress and strain in rat pulmonary artery material during a biaxial bubble test. Biomed Sci Instrum. 2004; 40:303-8. PMID: 15133975.
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    90. Yue X, Hwang FN, Shandas R, Cai XC. Simulation of branching blood flows on parallel computers. Biomed Sci Instrum. 2004; 40:325-30. PMID: 15133979.
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    91. Kim HB, Hertzberg JR, Shandas R. Echo PIV for flow field measurements in vivo. Biomed Sci Instrum. 2004; 40:357-63. PMID: 15133984.
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    92. Lanning C, Chen SY, Hansgen A, Chang D, Chan KC, Shandas R. Dynamic three-dimensional reconstruction and modeling of cardiovascular anatomy in children with congenital heart disease using biplane angiography. Biomed Sci Instrum. 2004; 40:200-5. PMID: 15133958.
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    93. Mukdadi O, Shandas R. Ultrasound wave propagation in tissue and scattering from microbubbles for echo particle image velocimetry technique. Biomed Sci Instrum. 2004; 40:364-70. PMID: 15133985.
      View in: PubMed
    94. Drost T, Zimmer T, Kim HB, Shandas R, Hertzberg J. Study of in vitro mitral valve filling flow. Biomed Sci Instrum. 2004; 40:350-6. PMID: 15133983.
      View in: PubMed
    95. Zheng H, Mukdadi O, Hertzberg J, Shandas R. Advantages in using multi-frequency driving ultrasound for optimizing echo particle image velocimetry techniques. Biomed Sci Instrum. 2004; 40:371-6. PMID: 15133986.
      View in: PubMed
    96. Liu LL, Mukdadi OM, Hertzberg JR, Shandas R. A model study of capacitive micromachined ultrasonic transducers fabricated using atomic layer deposition process. Biomed Sci Instrum. 2004; 40:142-8. PMID: 15133949.
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    97. Khunatorn Y, Shandas R, DeGroff C, Mahalingam S. Comparison of in vitro velocity measurements in a scaled total cavopulmonary connection with computational predictions. Ann Biomed Eng. 2003 Jul-Aug; 31(7):810-22. PMID: 12971614.
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    98. DeGroff CG, Orlando W, Shandas R. Insights into the effect of aortic compliance on Doppler diastolic flow patterns seen in coarctation of the aorta: a numeric study. J Am Soc Echocardiogr. 2003 Feb; 16(2):162-9. PMID: 12574743.
      View in: PubMed
    99. Weinberg CE, Hertzberg JR, Shandas R. Use of intravascular ultrasound to measure local compliance of the pediatric pulmonary artery: in vitro studies. J Am Soc Echocardiogr. 2002 Dec; 15(12):1507-14. PMID: 12464920.
      View in: PubMed
    100. DeGroff CG, Shandas R. Designing the optimal Total Cavopulmonary Connection: pulsatile versus steady flow experiments. Med Sci Monit. 2002 Mar; 8(3):MT41-5. PMID: 11887040.
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    101. DeGroff CG, Carlton JD, Weinberg CE, Ellison MC, Shandas R, Valdes-Cruz L. Effect of vessel size on the flow efficiency of the total cavopulmonary connection: in vitro studies. Pediatr Cardiol. 2002 Mar-Apr; 23(2):171-7. PMID: 11889529.
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    102. Collier E, Hertzberg J, Shandas R. Regression analysis for vortex ring characteristics during left ventricular filling. Biomed Sci Instrum. 2002; 38:307-11. PMID: 12085622.
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    103. Orlando W, Hertzberg J, Shandas R, DeGroff C. Reverse flow in compliant vessels and its implications for the Fontan procedure: numerical studies. Biomed Sci Instrum. 2002; 38:321-6. PMID: 12085625.
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    104. DeGroff CG, Shandas R, Kwon J, Valdes-Cruz L. Accuracy of the Bernoulli equation for estimation of pressure gradient across stenotic Blalock-Taussig shunts: an in vitro and numerical study. Pediatr Cardiol. 2000 Sep-Oct; 21(5):439-47. PMID: 10982702.
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    105. DeGroff CG, Shandas R, Valdes-Cruz L. Utility of the proximal jet width in the assessment of regurgitant and stenotic orifices--effect of low velocity filter and comparison to actual vena contracta width: an in vitro and numerical study. Eur J Echocardiogr. 2000 Mar; 1(1):42-54. PMID: 12086216.
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    106. Shandas R, Kwon J, Valdes-Cruz L. Real-time 3-dimensional volumetric ultrasound imaging of the vena contracta for stenotic valves with the use of echocardiographic contrast imaging: in vitro pulsatile flow studies. J Am Soc Echocardiogr. 1999 Jul; 12(7):541-50. PMID: 10398912.
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    107. Lemler MS, Valdes-Cruz LM, Shandas RS, Cape EG. Insights into catheter/Doppler discrepancies in congenital aortic stenosis. Am J Cardiol. 1999 May 15; 83(10):1447-50. PMID: 10335760.
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    108. DeGroff CG, Shandas R, Valdes-Cruz L. Analysis of the effect of flow rate on the Doppler continuity equation for stenotic orifice area calculations: a numerical study. Circulation. 1998 Apr 28; 97(16):1597-605. PMID: 9593565.
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