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Jerome Schaack

TitleAssociate Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM-Immunology Microbiology

    Collapse Research 
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    R01GM042555     (SCHAACK, JEROME BYRNE)Sep 1, 1991 - Aug 31, 1995
    Role: Principal Investigator

    R01HL058344     (SCHAACK, JEROME BYRNE)Sep 30, 1996 - Aug 31, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Qiao L, Wattez JS, Lee S, Nguyen A, Schaack J, Hay WW, Shao J. Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice. Diabetes. 2017 05; 66(5):1126-1135. PMID: 28073830.
      View in: PubMed
    2. Qiao L, Wattez JS, Lee S, Guo Z, Schaack J, Hay WW, Zita MM, Parast M, Shao J. Knockout maternal adiponectin increases fetal growth in mice: potential role for trophoblast IGFBP-1. Diabetologia. 2016 11; 59(11):2417-2425. PMID: 27495989.
      View in: PubMed
    3. Zhou Q, Abraham AD, Li L, Babalmorad A, Bagby S, Arcaroli JJ, Hansen RJ, Valeriote FA, Gustafson DL, Schaack J, Messersmith WA, LaBarbera DV. Topoisomerase IIa mediates TCF-dependent epithelial-mesenchymal transition in colon cancer. Oncogene. 2016 09 22; 35(38):4990-9. PMID: 26947016.
      View in: PubMed
    4. Modiano JF, Lindborg BA, McElmurry RT, Lewellen M, Forster CL, Zamora EA, Schaack J, Bellgrau D, O'Brien TD, Tolar J. Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment. Cancer Immunol Immunother. 2015 Nov; 64(11):1449-60. PMID: 26250807.
      View in: PubMed
    5. Qiao L, Guo Z, Bosco C, Guidotti S, Wang Y, Wang M, Parast M, Schaack J, Hay WW, Moore TR, Shao J. Maternal High-Fat Feeding Increases Placental Lipoprotein Lipase Activity by Reducing SIRT1 Expression in Mice. Diabetes. 2015 Sep; 64(9):3111-20. PMID: 25948680; PMCID: PMC4542442.
    6. Banda NK, Mehta G, Kjaer TR, Takahashi M, Schaack J, Morrison TE, Thiel S, Arend WP, Holers VM. Essential role for the lectin pathway in collagen antibody-induced arthritis revealed through use of adenovirus programming complement inhibitor MAp44 expression. J Immunol. 2014 Sep 01; 193(5):2455-68. PMID: 25070856; PMCID: PMC4134985.
    7. Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J. C/EBPa regulates macrophage activation and systemic metabolism. Am J Physiol Endocrinol Metab. 2014 May 15; 306(10):E1144-54. PMID: 24691027; PMCID: PMC4025063.
    8. Qiao L, Yoo Hs, Bosco C, Lee B, Feng GS, Schaack J, Chi NW, Shao J. Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice. Diabetologia. 2014 May; 57(5):1027-36. PMID: 24531262; PMCID: PMC4077285.
    9. Yang X, La Rosa FG, Genova EE, Huber K, Schaack J, Degregori J, Serkova NJ, Li Y, Su LJ, Kessler E, Flaig TW. Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia. PLoS One. 2013; 8(9):e74809. PMID: 24058630; PMCID: PMC3776760.
    10. Ahmad A, Ahmad S, Malcolm KC, Miller SM, Hendry-Hofer T, Schaack JB, White CW. Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1a and hypoxia-inducible transcription factor-2a. Am J Respir Cell Mol Biol. 2013 Jul; 49(1):78-85. PMID: 23492195; PMCID: PMC3727885.
    11. Jeong J, Lisinski I, Kadegowda AK, Shin H, Wooding FB, Daniels BR, Schaack J, Mather IH. A test of current models for the mechanism of milk-lipid droplet secretion. Traffic. 2013 Sep; 14(9):974-86. PMID: 23738536; PMCID: PMC4524534.
    12. Ahmad A, Schaack JB, White CW, Ahmad S. Adenosine A2A receptor-dependent proliferation of pulmonary endothelial cells is mediated through calcium mobilization, PI3-kinase and ERK1/2 pathways. Biochem Biophys Res Commun. 2013 May 10; 434(3):566-71. PMID: 23583199; PMCID: PMC4046330.
    13. Axlund SD, Yoo BH, Rosen RB, Schaack J, Kabos P, Labarbera DV, Sartorius CA. Progesterone-inducible cytokeratin 5-positive cells in luminal breast cancer exhibit progenitor properties. Horm Cancer. 2013 Feb; 4(1):36-49. PMID: 23184698; PMCID: PMC3549640.
    14. Qadri I, Choudhury M, Rahman SM, Knotts TA, Janssen RC, Schaack J, Iwahashi M, Puljak L, Simon FR, Kilic G, Fitz JG, Friedman JE. Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein ß. J Biol Chem. 2012 Oct 26; 287(44):37340-51. PMID: 22955269; PMCID: PMC3481331.
    15. Modiano JF, Bellgrau D, Cutter GR, Lana SE, Ehrhart NP, Ehrhart E, Wilke VL, Charles JB, Munson S, Scott MC, Pozniak J, Carlson CS, Schaack J, Duke RC. Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer. Mol Ther. 2012 Dec; 20(12):2234-43. PMID: 22850679; PMCID: PMC3519983.
    16. Yoo BH, Axlund SD, Kabos P, Reid BG, Schaack J, Sartorius CA, LaBarbera DV. A high-content assay to identify small-molecule modulators of a cancer stem cell population in luminal breast cancer. J Biomol Screen. 2012 Oct; 17(9):1211-20. PMID: 22751729; PMCID: PMC4158006.
    17. Qiao L, Kinney B, Yoo HS, Lee B, Schaack J, Shao J. Adiponectin increases skeletal muscle mitochondrial biogenesis by suppressing mitogen-activated protein kinase phosphatase-1. Diabetes. 2012 Jun; 61(6):1463-70. PMID: 22415879; PMCID: PMC3357265.
    18. Willenborg C, Jing J, Wu C, Matern H, Schaack J, Burden J, Prekeris R. Interaction between FIP5 and SNX18 regulates epithelial lumen formation. J Cell Biol. 2011 Oct 03; 195(1):71-86. PMID: 21969467; PMCID: PMC3187708.
    19. Russell TD, Schaack J, Orlicky DJ, Palmer C, Chang BH, Chan L, McManaman JL. Adipophilin regulates maturation of cytoplasmic lipid droplets and alveolae in differentiating mammary glands. J Cell Sci. 2011 Oct 01; 124(Pt 19):3247-53. PMID: 21878492.
      View in: PubMed
    20. Qiao L, Kinney B, Schaack J, Shao J. Adiponectin inhibits lipolysis in mouse adipocytes. Diabetes. 2011 May; 60(5):1519-27. PMID: 21430087; PMCID: PMC3292326.
    21. Doherty FC, Schaack JB, Sladek CD. Comparison of the efficacy of four viral vectors for transducing hypothalamic magnocellular neurosecretory neurons in the rat supraoptic nucleus. J Neurosci Methods. 2011 Apr 30; 197(2):238-48. PMID: 21392530; PMCID: PMC3085541.
    22. Chong BM, Russell TD, Schaack J, Orlicky DJ, Reigan P, Ladinsky M, McManaman JL. The adipophilin C terminus is a self-folding membrane-binding domain that is important for milk lipid secretion. J Biol Chem. 2011 Jul 01; 286(26):23254-65. PMID: 21383012.
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    23. Li Q, Chen C, Kapadia A, Zhou Q, Harper MK, Schaack J, LaBarbera DV. 3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen. J Biomol Screen. 2011 Feb; 16(2):141-54. PMID: 21297102.
      View in: PubMed
    24. Schaack J, Qiao L, Walkiewicz MP, Stonehouse M, Engel DA, Vazquez-Torres A, Nordeen SK, Shao J, Moorhead JW. Insertion of CTCF-binding sites into a first-generation adenovirus vector reduces the innate inflammatory response and prolongs transgene expression. Virology. 2011 Mar 30; 412(1):136-45. PMID: 21272906.
      View in: PubMed
    25. Schaack J, Bennett ML, Shapiro GS, DeGregori J, McManaman JL, Moorhead JW. Strong foreign promoters contribute to innate inflammatory responses induced by adenovirus transducing vectors. Virology. 2011 Mar 30; 412(1):28-35. PMID: 21255815; PMCID: PMC4419336.
    26. Beeman NE, Baumgartner HK, Webb PG, Schaack JB, Neville MC. Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistance. BMC Cell Biol. 2009 Dec 09; 10:85. PMID: 20003227; PMCID: PMC2796999.
    27. Cantu D, Schaack J, Patel M. Oxidative inactivation of mitochondrial aconitase results in iron and H2O2-mediated neurotoxicity in rat primary mesencephalic cultures. PLoS One. 2009 Sep 18; 4(9):e7095. PMID: 19763183.
      View in: PubMed
    28. Ahmad A, Ahmad S, Glover L, Miller SM, Shannon JM, Guo X, Franklin WA, Bridges JP, Schaack JB, Colgan SP, White CW. Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10684-9. PMID: 19541651; PMCID: PMC2705563.
    29. Nichols GJ, Schaack J, Ornelles DA. Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication. J Virol. 2009 Jun; 83(12):5987-98. PMID: 19321613; PMCID: PMC2687384.
    30. Jubala CM, Lamerato-Kozicki AR, Borakove M, Lang J, Gardner LA, Coffey D, Helm KM, Schaack J, Baier M, Cutter GR, Bellgrau D, Modiano JF. MHC-dependent desensitization of intrinsic anti-self reactivity. Cancer Immunol Immunother. 2009 Feb; 58(2):171-85. PMID: 18523772; PMCID: PMC2585149.
    31. Qiao L, Zou C, Shao P, Schaack J, Johnson PF, Shao J. Transcriptional regulation of fatty acid translocase/CD36 expression by CCAAT/enhancer-binding protein alpha. J Biol Chem. 2008 Apr 04; 283(14):8788-95. PMID: 18263877; PMCID: PMC2276366.
    32. Humphries MJ, Ohm AM, Schaack J, Adwan TS, Reyland ME. Tyrosine phosphorylation regulates nuclear translocation of PKCdelta. Oncogene. 2008 May 08; 27(21):3045-53. PMID: 18059334; PMCID: PMC3285468.
    33. McManaman JL, Russell TD, Schaack J, Orlicky DJ, Robenek H. Molecular determinants of milk lipid secretion. J Mammary Gland Biol Neoplasia. 2007 Dec; 12(4):259-68. PMID: 17999166.
      View in: PubMed
    34. Gommans WM, Oosterhuis D, Dmitriev I, Schaack J, Curiel DT, Haisma HJ, Rots MG. Towards a double controlled conditionally replicative adenovirus for potent and specific melanoma cell kill. J Control Release. 2006 Nov 28; 116(2):e64-6. PMID: 17718975.
      View in: PubMed
    35. Buser AC, Gass-Handel EK, Wyszomierski SL, Doppler W, Leonhardt SA, Schaack J, Rosen JM, Watkin H, Anderson SM, Edwards DP. Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol. 2007 Jan; 21(1):106-25. PMID: 16973758.
      View in: PubMed
    36. Shapiro GS, Van Peursem C, Ornelles DA, Schaack J, DeGregori J. Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein. J Virol. 2006 Jun; 80(11):5349-60. PMID: 16699015; PMCID: PMC1472169.
    37. Willoughby D, Wong W, Schaack J, Scott JD, Cooper DM. An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics. EMBO J. 2006 May 17; 25(10):2051-61. PMID: 16642035; PMCID: PMC1462982.
    38. Qiao L, MacLean PS, You H, Schaack J, Shao J. knocking down liver ccaat/enhancer-binding protein alpha by adenovirus-transduced silent interfering ribonucleic acid improves hepatic gluconeogenesis and lipid homeostasis in db/db mice. Endocrinology. 2006 Jun; 147(6):3060-9. PMID: 16543372.
      View in: PubMed
    39. Qiao L, Schaack J, Shao J. Suppression of adiponectin gene expression by histone deacetylase inhibitor valproic acid. Endocrinology. 2006 Feb; 147(2):865-74. PMID: 16282359.
      View in: PubMed
    40. Ahmad A, Ahmad S, Chang LY, Schaack J, White CW. Endothelial Akt activation by hyperoxia: role in cell survival. Free Radic Biol Med. 2006 Apr 01; 40(7):1108-18. PMID: 16545678.
      View in: PubMed
    41. Qiao L, Maclean PS, Schaack J, Orlicky DJ, Darimont C, Pagliassotti M, Friedman JE, Shao J. C/EBPalpha regulates human adiponectin gene transcription through an intronic enhancer. Diabetes. 2005 Jun; 54(6):1744-54. PMID: 15919796.
      View in: PubMed
    42. Schaack J. Adenovirus vectors deleted for genes essential for viral DNA replication. Front Biosci. 2005 May 01; 10:1146-55. PMID: 15769613.
      View in: PubMed
    43. Schaack J. Induction and inhibition of innate inflammatory responses by adenovirus early region proteins. Viral Immunol. 2005; 18(1):79-88. PMID: 15802954.
      View in: PubMed
    44. Qadri I, Iwahashi M, Capasso JM, Hopken MW, Flores S, Schaack J, Simon FR. Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1. Biochem J. 2004 Mar 15; 378(Pt 3):919-28. PMID: 14670077; PMCID: PMC1224028.
    45. Schaack J, Bennett ML, Colbert JD, Torres AV, Clayton GH, Ornelles D, Moorhead J. E1A and E1B proteins inhibit inflammation induced by adenovirus. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):3124-9. PMID: 14976240; PMCID: PMC365754.
    46. Köhrer C, Yoo JH, Bennett M, Schaack J, RajBhandary UL. A possible approach to site-specific insertion of two different unnatural amino acids into proteins in mammalian cells via nonsense suppression. Chem Biol. 2003 Nov; 10(11):1095-102. PMID: 14652077.
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    47. Bennett M, Schaack J. Development of a dual-luciferase fusion gene as a sensitive marker for site-directed DNA repair strategies. J Gene Med. 2003 Aug; 5(8):723-32. PMID: 12898641.
      View in: PubMed
    48. Russell TD, Fischer A, Beeman NE, Freed EF, Neville MC, Schaack J. Transduction of the mammary epithelium with adenovirus vectors in vivo. J Virol. 2003 May; 77(10):5801-9. PMID: 12719573; PMCID: PMC154007.
    49. McManaman JL, Zabaronick W, Schaack J, Orlicky DJ. Lipid droplet targeting domains of adipophilin. J Lipid Res. 2003 Apr; 44(4):668-73. PMID: 12562852.
      View in: PubMed
    50. Galan HL, Bennett ML, Tyson RW, Owens G, Regnault TR, Accurso F, Hobbins JC, Schaack J. Inefficient transduction of sheep in utero after intra-amniotic injection of retroviral producer cells. Am J Obstet Gynecol. 2002 Aug; 187(2):469-74. PMID: 12193945.
      View in: PubMed
    51. Cota-Gomez A, Flores NC, Cruz C, Casullo A, Aw TY, Ichikawa H, Schaack J, Scheinman R, Flores SC. The human immunodeficiency virus-1 Tat protein activates human umbilical vein endothelial cell E-selectin expression via an NF-kappa B-dependent mechanism. J Biol Chem. 2002 Apr 26; 277(17):14390-9. PMID: 11827962.
      View in: PubMed
    52. Zhou W, Schaack J, Zawada WM, Freed CR. Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture. Brain Res. 2002 Feb 01; 926(1-2):42-50. PMID: 11814405.
      View in: PubMed
    53. Allen MP, Linseman DA, Udo H, Xu M, Schaack JB, Varnum B, Kandel ER, Heidenreich KA, Wierman ME. Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase. Mol Cell Biol. 2002 Jan; 22(2):599-613. PMID: 11756555; PMCID: PMC139735.
    54. Roman R, Feranchak AP, Troetsch M, Dunkelberg JC, Kilic G, Schlenker T, Schaack J, Fitz JG. Molecular characterization of volume-sensitive SK(Ca) channels in human liver cell lines. Am J Physiol Gastrointest Liver Physiol. 2002 Jan; 282(1):G116-22. PMID: 11751164.
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    55. Schaack J, Allen B, Orlicky DJ, Bennett ML, Maxwell IH, Smith RL. Promoter strength in adenovirus transducing vectors: down-regulation of the adenovirus E1A promoter in 293 cells facilitates vector construction. Virology. 2001 Dec 05; 291(1):101-9. PMID: 11878880.
      View in: PubMed
    56. Rich TC, Fagan KA, Tse TE, Schaack J, Cooper DM, Karpen JW. A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cell. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13049-54. PMID: 11606735; PMCID: PMC60822.
    57. Bennett M, Galan H, Owens G, Dewey R, Banks R, Hobbins J, Accurso F, Schaack J. In utero gene delivery by intraamniotic injection of a retroviral vector producer cell line in a nonhuman primate model. Hum Gene Ther. 2001 Oct 10; 12(15):1857-65. PMID: 11589828.
      View in: PubMed
    58. Klemm DJ, Watson PA, Frid MG, Dempsey EC, Schaack J, Colton LA, Nesterova A, Stenmark KR, Reusch JE. cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J Biol Chem. 2001 Dec 07; 276(49):46132-41. PMID: 11560924.
      View in: PubMed
    59. Rich TC, Tse TE, Rohan JG, Schaack J, Karpen JW. In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors. J Gen Physiol. 2001 Jul; 118(1):63-78. PMID: 11429444; PMCID: PMC2233745.
    60. Fagan KA, Schaack J, Zweifach A, Cooper DM. Adenovirus encoded cyclic nucleotide-gated channels: a new methodology for monitoring cAMP in living cells. FEBS Lett. 2001 Jun 29; 500(1-2):85-90. PMID: 11434932.
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    61. Orlicky DJ, DeGregori J, Schaack J. Construction of stable coxsackievirus and adenovirus receptor-expressing 3T3-L1 cells. J Lipid Res. 2001 Jun; 42(6):910-5. PMID: 11369798.
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    62. Orlicky DJ, Schaack J. Adenovirus transduction of 3T3-L1 cells. J Lipid Res. 2001 Mar; 42(3):460-6. PMID: 11254759.
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    63. Thomas DL, Schaack J, Vogel H, Javier R. Several E4 region functions influence mammary tumorigenesis by human adenovirus type 9. J Virol. 2001 Jan; 75(2):557-68. PMID: 11134268; PMCID: PMC113951.
    64. Fagan KA, Graf RA, Tolman S, Schaack J, Cooper DM. Regulation of a Ca2+-sensitive adenylyl cyclase in an excitable cell. Role of voltage-gated versus capacitative Ca2+ entry. J Biol Chem. 2000 Dec 22; 275(51):40187-94. PMID: 11010970.
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    65. Wan YY, Leon RP, Marks R, Cham CM, Schaack J, Gajewski TF, DeGregori J. Transgenic expression of the coxsackie/adenovirus receptor enables adenoviral-mediated gene delivery in naive T cells. Proc Natl Acad Sci U S A. 2000 Dec 05; 97(25):13784-9. PMID: 11095726; PMCID: PMC17653.
    66. Smith RL, Traul DL, Schaack J, Clayton GH, Staley KJ, Wilcox CL. Characterization of promoter function and cell-type-specific expression from viral vectors in the nervous system. J Virol. 2000 Dec; 74(23):11254-61. PMID: 11070024; PMCID: PMC113226.
    67. Rich TC, Fagan KA, Nakata H, Schaack J, Cooper DM, Karpen JW. Cyclic nucleotide-gated channels colocalize with adenylyl cyclase in regions of restricted cAMP diffusion. J Gen Physiol. 2000 Aug; 116(2):147-61. PMID: 10919863; PMCID: PMC2229499.
    68. Zhou W, Hurlbert MS, Schaack J, Prasad KN, Freed CR. Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells. Brain Res. 2000 Jun 02; 866(1-2):33-43. PMID: 10825478.
      View in: PubMed
    69. Schaack J, Ho WY, Tolman S, Ullyat E, Guo X, Frank N, Freimuth PI, Roovers DJ, Sussenbach JS. Construction and preliminary characterization of a library of "lethal" preterminal protein mutant adenoviruses. J Virol. 1999 Nov; 73(11):9599-603. PMID: 10516069; PMCID: PMC112995.
    70. Fagan KA, Rich TC, Tolman S, Schaack J, Karpen JW, Cooper DM. Adenovirus-mediated expression of an olfactory cyclic nucleotide-gated channel regulates the endogenous Ca2+-inhibitable adenylyl cyclase in C6-2B glioma cells. J Biol Chem. 1999 Apr 30; 274(18):12445-53. PMID: 10212219.
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    71. Hedlund TE, Meech SJ, Srikanth S, Kraft AS, Miller GJ, Schaack JB, Duke RC. Adenovirus-mediated expression of Fas ligand induces apoptosis of human prostate cancer cells. Cell Death Differ. 1999 Feb; 6(2):175-82. PMID: 10200564.
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    72. Moorhead JW, Clayton GH, Smith RL, Schaack J. A replication-incompetent adenovirus vector with the preterminal protein gene deleted efficiently transduces mouse ears. J Virol. 1999 Feb; 73(2):1046-53. PMID: 9882305; PMCID: PMC103924.
    73. Leon RP, Hedlund T, Meech SJ, Li S, Schaack J, Hunger SP, Duke RC, DeGregori J. Adenoviral-mediated gene transfer in lymphocytes. Proc Natl Acad Sci U S A. 1998 Oct 27; 95(22):13159-64. PMID: 9789058; PMCID: PMC23744.
    74. Maxwell IH, Maxwell F, Schaack J. An adenovirus type 5 mutant with the preterminal protein gene deleted efficiently provides helper functions for the production of recombinant adeno-associated virus. J Virol. 1998 Oct; 72(10):8371-3. PMID: 9733887; PMCID: PMC110217.
    75. Reed DS, Romero P, Rimoldi D, Cerottini JC, Schaack J, Jongeneel CV. Construction and characterization of a recombinant adenovirus directing expression of the MAGE-1 tumor-specific antigen. Int J Cancer. 1997 Sep 17; 72(6):1045-55. PMID: 9378539.
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    76. Schaack J, Guo X, Langer SJ. Characterization of a replication-incompetent adenovirus type 5 mutant deleted for the preterminal protein gene. Proc Natl Acad Sci U S A. 1996 Dec 10; 93(25):14686-91. PMID: 8962115; PMCID: PMC26196.
    77. Kaddis FG, Zawada WM, Schaack J, Freed CR. Conditioned medium from aged monkey fibroblasts stably expressing GDNF and BDNF improves survival of embryonic dopamine neurons in vitro. Cell Tissue Res. 1996 Nov; 286(2):241-7. PMID: 8854893.
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    78. Qadri I, Conaway JW, Conaway RC, Schaack J, Siddiqui A. Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH. Proc Natl Acad Sci U S A. 1996 Oct 01; 93(20):10578-83. PMID: 8855220; PMCID: PMC38195.
    79. Staley K, Smith R, Schaack J, Wilcox C, Jentsch TJ. Alteration of GABAA receptor function following gene transfer of the CLC-2 chloride channel. Neuron. 1996 Sep; 17(3):543-51. PMID: 8816717.
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    80. Langer SJ, Schaack J. 293 cell lines that inducibly express high levels of adenovirus type 5 precursor terminal protein. Virology. 1996 Jul 01; 221(1):172-9. PMID: 8661425.
      View in: PubMed
    81. Schaack J, Maguire HF, Siddiqui A. Hepatitis B virus X protein partially substitutes for E1A transcriptional function during adenovirus infection. Virology. 1996 Feb 15; 216(2):425-30. PMID: 8607273.
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    82. Schaack J, Guo X, Ho WY, Karlok M, Chen C, Ornelles D. Adenovirus type 5 precursor terminal protein-expressing 293 and HeLa cell lines. J Virol. 1995 Jul; 69(7):4079-85. PMID: 7769665; PMCID: PMC189142.
    83. Schaack J, Langer S, Guo X. Efficient selection of recombinant adenoviruses by vectors that express beta-galactosidase. J Virol. 1995 Jun; 69(6):3920-3. PMID: 7745747; PMCID: PMC189118.
    84. Vakalopoulou E, Schaack J, Shenk T. A 32-kilodalton protein binds to AU-rich domains in the 3' untranslated regions of rapidly degraded mRNAs. Mol Cell Biol. 1991 Jun; 11(6):3355-64. PMID: 1903842; PMCID: PMC360189.
    85. Schaack J, Logan J, Vakalopoulou E, Shenk T. Adenovirus E1A protein activates transcription of the E1A gene subsequent to transcription complex formation. J Virol. 1991 Apr; 65(4):1687-94. PMID: 1825853; PMCID: PMC239972.
    86. Schaack J, Ho WY, Freimuth P, Shenk T. Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA. Genes Dev. 1990 Jul; 4(7):1197-208. PMID: 2210375.
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    87. Schaack J, Schedl P, Shenk T. Topoisomerase I and II cleavage of adenovirus DNA in vivo: both topoisomerase activities appear to be required for adenovirus DNA replication. J Virol. 1990 Jan; 64(1):78-85. PMID: 2152835; PMCID: PMC249049.
    88. Schaack J, Shenk T. Adenovirus terminal protein mediates efficient and timely activation of viral transcription. Curr Top Microbiol Immunol. 1989; 144:185-90. PMID: 2791638.
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    89. Moore M, Schaack J, Baim SB, Morimoto RI, Shenk T. Induced heat shock mRNAs escape the nucleocytoplasmic transport block in adenovirus-infected HeLa cells. Mol Cell Biol. 1987 Dec; 7(12):4505-12. PMID: 3437895; PMCID: PMC368135.
    90. Cooley L, Schaack J, Burke DJ, Thomas B, Söll D. Transcription factor binding is limited by the 5'-flanking regions of a Drosophila tRNAHis gene and a tRNAHis pseudogene. Mol Cell Biol. 1984 Dec; 4(12):2714-22. PMID: 6570190; PMCID: PMC369281.
    91. Schaack J, Sharp S, Dingermann T, Burke DJ, Cooley L, Söll D. The extent of a eukaryotic tRNA gene. 5'- and 3'-flanking sequence dependence for transcription and stable complex formation. J Biol Chem. 1984 Feb 10; 259(3):1461-7. PMID: 6693417.
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