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Hany Abdel-Hafiz

TitleAssoc Professor-Research
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Fatima K, Mathew S, Faheem M, Mehmood T, Yassine HM, Al Thani AA, Abdel-Hafiz H, Al Ghamdy K, Qadri I. The dual specificity role of transcription factor FOXO in type 2-diabetes and cancer. Curr Pharm Des. 2018 Sep 10. PMID: 30205794.
      View in: PubMed
    2. Suhail M, Sohrab SS, Qureshi A, Tarique M, Abdel-Hafiz H, Al-Ghamdi K, Qadri I. Association of HCV mutated proteins and host SNPs in the development of hepatocellular carcinoma. Infect Genet Evol. 2018 Jun; 60:160-172. PMID: 29501636.
      View in: PubMed
    3. Abdel-Hafiz HA, Dudevoir ML, Perez D, Abdel-Hafiz M, Horwitz KB. SUMOylation Regulates Transcription by the Progesterone Receptor A Isoform in a Target Gene Selective Manner. Diseases. 2018 Jan 02; 6(1). PMID: 29301281.
      View in: PubMed
    4. Abdel-Hafiz HA. Epigenetic Mechanisms of Tamoxifen Resistance in Luminal Breast Cancer. Diseases. 2017 Jul 06; 5(3). PMID: 28933369.
      View in: PubMed
    5. Mathew S, Abdel-Hafiz H, Raza A, Fatima K, Qadri I. Host nucleotide polymorphism in hepatitis B virus-associated hepatocellular carcinoma. World J Hepatol. 2016 Apr 08; 8(10):485-98. PMID: 27057306; PMCID: PMC4820640.
    6. Abdel-Hafiz HA, Horwitz KB. Role of epigenetic modifications in luminal breast cancer. Epigenomics. 2015 Aug; 7(5):847-62. PMID: 25689414; PMCID: PMC4539290.
    7. Suhail M, Abdel-Hafiz H, Ali A, Fatima K, Damanhouri GA, Azhar E, Chaudhary AG, Qadri I. Potential mechanisms of hepatitis B virus induced liver injury. World J Gastroenterol. 2014 Sep 21; 20(35):12462-72. PMID: 25253946; PMCID: PMC4168079.
    8. Ali A, Abdel-Hafiz H, Suhail M, Al-Mars A, Zakaria MK, Fatima K, Ahmad S, Azhar E, Chaudhary A, Qadri I. Hepatitis B virus, HBx mutants and their role in hepatocellular carcinoma. World J Gastroenterol. 2014 Aug 14; 20(30):10238-48. PMID: 25132741; PMCID: PMC4130832.
    9. Knox AJ, Scaling AL, Pinto MP, Bliesner BS, Haughian JM, Abdel-Hafiz HA, Horwitz KB. Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease. Breast Cancer Res. 2014 Aug 13; 16(4):418. PMID: 25116921; PMCID: PMC4187339.
    10. Mathew S, Ali A, Abdel-Hafiz H, Fatima K, Suhail M, Archunan G, Begum N, Jahangir S, Ilyas M, Chaudhary AG, Al Qahtani M, Mohamad Bazarah S, Qadri I. Biomarkers for virus-induced hepatocellular carcinoma (HCC). Infect Genet Evol. 2014 Aug; 26:327-39. PMID: 24956436.
      View in: PubMed
    11. Abdel-Hafiz HA, Horwitz KB. Post-translational modifications of the progesterone receptors. J Steroid Biochem Mol Biol. 2014 Mar; 140:80-9. PMID: 24333793; PMCID: PMC3923415.
    12. Abdel-Hafiz HA, Horwitz KB. Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation. BMC Mol Biol. 2012 Mar 22; 13:10. PMID: 22439847; PMCID: PMC3373386.
    13. Abdel-Hafiz HA. Role of Hepatitis B virus X Protein in DNA Repair During Hepatocellular Carcinoma Development. J Carcinogene Mutagene. 2011; 1(3).
    14. Qadri I, Fatima K, AbdeL-Hafiz H. Hepatitis B virus X protein impedes the DNA repair via its association with transcription factor, TFIIH. BMC Microbiol. 2011 Mar 04; 11:48. PMID: 21375739; PMCID: PMC3060106.
    15. Ramzy MM, Solliman MM, Abdel-Hafiz HA, Salah R. Genetic polymorphism of GSTM1 and GSTP1 in lung cancer in Egypt. International J. Collaborative Research on Internal Medicine & Public Health. 2011; 2(1):41-51.
    16. Abdel-Hafiz H, Dudevoir ML, Horwitz KB. Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation. J Biol Chem. 2009 Apr 03; 284(14):9099-108. PMID: 19211567; PMCID: PMC2666559.
    17. Lange CA, Sartorius CA, Abdel-Hafiz H, Spillman MA, Horwitz KB, Jacobsen BM. Progesterone receptor action: translating studies in breast cancer models to clinical insights. Adv Exp Med Biol. 2008; 630:94-111. PMID: 18637487.
      View in: PubMed
    18. Jones MC, Fusi L, Higham JH, Abdel-Hafiz H, Horwitz KB, Lam EW, Brosens JJ. Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44):16272-7. PMID: 17053081; PMCID: PMC1637572.
    19. Tung L, Abdel-Hafiz H, Shen T, Harvell DM, Nitao LK, Richer JK, Sartorius CA, Takimoto GS, Horwitz KB. Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B. Mol Endocrinol. 2006 Nov; 20(11):2656-70. PMID: 16762974.
      View in: PubMed
    20. Mohammed NA, Abd El-Aleem SA, El-Hafiz HA, McMahon RF, El-Aleem SA. Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: a possible role for COX-2 in the pathogenesis of liver cirrhosis. J Clin Pathol. 2004 Apr; 57(4):350-4. PMID: 15047734; PMCID: PMC1770276.
    21. Takimoto GS, Tung L, Abdel-Hafiz H, Abel MG, Sartorius CA, Richer JK, Jacobsen BM, Bain DL, Horwitz KB. Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure. J Steroid Biochem Mol Biol. 2003 Jun; 85(2-5):209-19. PMID: 12943706.
      View in: PubMed
    22. Abdel-Hafiz H, Takimoto GS, Tung L, Horwitz KB. The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression. J Biol Chem. 2002 Sep 13; 277(37):33950-6. PMID: 12114521.
      View in: PubMed
    23. Kroll DJ, Abdel-Malek Abdel-Hafiz H, Marcell T, Simpson S, Chen CY, Gutierrez-Hartmann A, Lustbader JW, Hoeffler JP. A multifunctional prokaryotic protein expression system: overproduction, affinity purification, and selective detection. DNA Cell Biol. 1993 Jun; 12(5):441-53. PMID: 7686011.
      View in: PubMed
    24. Abdel-Hafiz HA, Chen CY, Marcell T, Kroll DJ, Hoeffler JP. Structural determinants outside of the leucine zipper influence the interactions of CREB and ATF-2: interaction of CREB with ATF-2 blocks E1a-ATF-2 complex formation. Oncogene. 1993 May; 8(5):1161-74. PMID: 8479741.
      View in: PubMed
    25. Abdel-Hafiz HA, Heasley LE, Kyriakis JM, Avruch J, Kroll DJ, Johnson GL, Hoeffler JP. Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases. Mol Endocrinol. 1992 Dec; 6(12):2079-89. PMID: 1337144.
      View in: PubMed
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