Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Isabel R Schlaepfer

TitleInstructor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOM - Pharmacology
Address2RC1N
Research North Tower
12800 E 19th Ave, Bldg. RC1 North Room P18-9103
Aurora CO 80010
Phone303/724-3365

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Schlaepfer IR, Hitz CA, Gijón MA, Bergman BC, Eckel RH, Jacobsen BM. Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxel. Mol Cell Endocrinol. 2012 Nov 5; 363(1-2):111-21.
    View in: PubMed
  2. Stephens SH, Hoft NR, Schlaepfer IR, Young SE, Corley RC, McQueen MB, Hopfer C, Crowley T, Stallings M, Hewitt J, Ehringer MA. Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster. Behav Genet. 2012 May; 42(3):402-14.
    View in: PubMed
  3. Capell WH, Schlaepfer IR, Wolfe P, Watson PA, Bessesen DH, Pagliassotti MJ, Eckel RH. Fatty acids increase glucose uptake and metabolism in C2C12 myoblasts stably transfected with human lipoprotein lipase. Am J Physiol Endocrinol Metab. 2010 Oct; 299(4):E576-83.
    View in: PubMed
  4. Hoft NR, Corley RP, McQueen MB, Schlaepfer IR, Huizinga D, Ehringer MA. Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample. Neuropsychopharmacology. 2009 Feb; 34(3):698-706.
    View in: PubMed
  5. Schlaepfer IR, Hoft NR, Ehringer MA. The genetic components of alcohol and nicotine co-addiction: from genes to behavior. Curr Drug Abuse Rev. 2008 Jun; 1(2):124-34.
    View in: PubMed
  6. Schlaepfer IR, Hoft NR, Collins AC, Corley RP, Hewitt JK, Hopfer CJ, Lessem JM, McQueen MB, Rhee SH, Ehringer MA. The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults. Biol Psychiatry. 2008 Jun 1; 63(11):1039-46.
    View in: PubMed
  7. Zeiger JS, Haberstick BC, Schlaepfer I, Collins AC, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Lessem J, McQueen MB, Rhee SH, Ehringer MA. The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco. Hum Mol Genet. 2008 Mar 1; 17(5):724-34.
    View in: PubMed
  8. Ehringer MA, Clegg HV, Collins AC, Corley RP, Crowley T, Hewitt JK, Hopfer CJ, Krauter K, Lessem J, Rhee SH, Schlaepfer I, Smolen A, Stallings MC, Young SE, Zeiger JS. Association of the neuronal nicotinic receptor beta2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine. Am J Med Genet B Neuropsychiatr Genet. 2007 Jul 5; 144B(5):596-604.
    View in: PubMed
  9. Schlaepfer IR, Clegg HV, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Krauter K, Lessem J, Rhee SH, Stallings MC, Wehner JM, Young SE, Ehringer MA. The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition. Addict Biol. 2007 Jun; 12(2):200-9.
    View in: PubMed
  10. Schlaepfer IR, Pulawa LK, Eckel RH. Cloning and characterization of Munc18c(L), a novel murine Munc18c gene paralog. Biochem Biophys Res Commun. 2005 Sep 2; 334(3):911-6.
    View in: PubMed
  11. Schlaepfer IR, Pulawa LK, Ferreira LD, James DE, Capell WH, Eckel RH. Increased expression of the SNARE accessory protein Munc18c in lipid-mediated insulin resistance. J Lipid Res. 2003 Jun; 44(6):1174-81.
    View in: PubMed
  12. Poirier P, Marcell T, Huey PU, Schlaepfer IR, Owens GC, Jensen DR, Eckel RH. Increased intracellular triglyceride in C(2)C(12) muscle cells transfected with human lipoprotein lipase. Biochem Biophys Res Commun. 2000 Apr 21; 270(3):997-1001.
    View in: PubMed
  13. Schlaepfer IR, Eckel RH. Plasma triglyceride reduction in mice after direct injections of muscle-specific lipoprotein lipase DNA. Diabetes. 1999 Jan; 48(1):223-7.
    View in: PubMed
  14. Jensen DR, Schlaepfer IR, Morin CL, Pennington DS, Marcell T, Ammon SM, Gutierrez-Hartmann A, Eckel RH. Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase. Am J Physiol. 1997 Aug; 273(2 Pt 2):R683-9.
    View in: PubMed
  15. Eckel RH, Jensen DR, Schlaepfer IR, Yost TJ. Tissue-specific regulation of lipoprotein lipase by isoproterenol in normal-weight humans. Am J Physiol. 1996 Nov; 271(5 Pt 2):R1280-6.
    View in: PubMed
  16. Morin CL, Schlaepfer IR, Eckel RH. Tumor necrosis factor-alpha eliminates binding of NF-Y and an octamer-binding protein to the lipoprotein lipase promoter in 3T3-L1 adipocytes. J Clin Invest. 1995 Apr; 95(4):1684-9.
    View in: PubMed
  17. Schlaepfer IR, Mattoon JR, Bajszár G. The sequence and potential regulatory elements of the HEM2 promoter of Saccharomyces cerevisiae. Yeast. 1994 Feb; 10(2):227-9.
    View in: PubMed
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