 RNA, Messenger
"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
| Descriptor ID |
D012333
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| MeSH Number(s) |
D13.444.735.544
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| Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
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Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 11 | 36 | 47 | | 1995 | 8 | 34 | 42 | | 1996 | 2 | 42 | 44 | | 1997 | 4 | 43 | 47 | | 1998 | 11 | 43 | 54 | | 1999 | 4 | 39 | 43 | | 2000 | 7 | 47 | 54 | | 2001 | 2 | 39 | 41 | | 2002 | 8 | 46 | 54 | | 2003 | 9 | 83 | 92 | | 2004 | 13 | 72 | 85 | | 2005 | 7 | 68 | 75 | | 2006 | 10 | 85 | 95 | | 2007 | 9 | 66 | 75 | | 2008 | 13 | 55 | 68 | | 2009 | 11 | 52 | 63 | | 2010 | 11 | 58 | 69 | | 2011 | 15 | 46 | 61 | | 2012 | 21 | 53 | 74 | | 2013 | 9 | 47 | 56 | | 2014 | 14 | 48 | 62 | | 2015 | 10 | 60 | 70 | | 2016 | 16 | 39 | 55 | | 2017 | 11 | 40 | 51 | | 2018 | 12 | 39 | 51 | | 2019 | 14 | 20 | 34 | | 2020 | 12 | 32 | 44 | | 2021 | 9 | 24 | 33 | | 2022 | 1 | 49 | 50 | | 2023 | 0 | 30 | 30 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Barrington CL, Galindo G, Koch AL, Horton ER, Morrison EJ, Tisa S, Stasevich TJ, Rissland OS. Synonymous codon usage regulates translation initiation. Cell Rep. 2023 12 26; 42(12):113413.
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Powell TL, Barentsen K, Vaughan O, Uhlson C, Zemski Berry K, Erickson K, Faer K, Chassen SS, Jansson T. Knockdown of Placental Major Facilitator Superfamily Domain Containing 2a in Pregnant Mice Reduces Fetal Brain Growth and Phospholipid Docosahexaenoic Acid Content. Nutrients. 2023 Nov 29; 15(23).
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Farmer T, Vaeth KF, Han KJ, Goering R, Taliaferro MJ, Prekeris R. The role of midbody-associated mRNAs in regulating abscission. J Cell Biol. 2023 12 04; 222(12).
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Mansouri-Noori F, Pircher A, Bilodeau D, Siniavskaia L, Grigull J, Rissland OS, Bayfield MA. The LARP1 homolog Slr1p controls the stability and expression of proto-5'TOP mRNAs in fission yeast. Cell Rep. 2023 10 31; 42(10):113226.
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Hamm DC, Paatela EM, Bennett SR, Wong CJ, Campbell AE, Wladyka CL, Smith AA, Jagannathan S, Hsieh AC, Tapscott SJ. The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs. PLoS Biol. 2023 09; 21(9):e3002317.
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Maldonado L?pez AM, Ko EK, Huang S, Pacella G, Kuprasertkul N, D'souza CA, Reyes Hueros RA, Shen H, Stoute J, Elashal H, Sinkfield M, Anderson A, Prouty S, Li HB, Seykora JT, Liu KF, Capell BC. Mettl3-catalyzed m6A regulates histone modifier and modification expression in self-renewing somatic tissue. Sci Adv. 2023 09; 9(35):eadg5234.
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Maurina SF, O'Sullivan JP, Sharma G, Pineda Rodriguez DC, MacFadden A, Cendali F, Henen MA, V?geli B, Kieft JS, Glasgow A, Steckelberg AL. An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by ?-coronavirus Non-structural Protein 1. J Mol Biol. 2023 10 15; 435(20):168259.
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Shearn CT, Anderson AL, Devereaux MW, El Kasmi KC, Orlicky DJ, Sokol RJ. Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition. PLoS One. 2023; 18(8):e0290385.
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Kenigsberg TA, Goddard K, Hanson KE, Lewis N, Klein N, Irving SA, Naleway AL, Crane B, Kauffman TL, Xu S, Daley MF, Hurley LP, Kaiser R, Jackson LA, Jazwa A, Weintraub ES. Simultaneous administration of mRNA COVID-19 bivalent booster and influenza vaccines. Vaccine. 2023 09 07; 41(39):5678-5682.
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Link-Gelles R, Ciesla AA, Rowley EAK, Klein NP, Naleway AL, Payne AB, Kharbanda A, Natarajan K, DeSilva MB, Dascomb K, Irving SA, Zerbo O, Reese SE, Wiegand RE, Najdowski M, Ong TC, Rao S, Stockwell MS, Stephens A, Goddard K, Martinez YC, Weber ZA, Fireman B, Hansen J, Timbol J, Grannis SJ, Barron MA, Embi PJ, Ball SW, Gaglani M, Grisel N, Arndorfer J, Tenforde MW, Fleming-Dutra KE. Effectiveness of Monovalent and Bivalent mRNA Vaccines in Preventing COVID-19-Associated Emergency Department and Urgent Care Encounters Among Children Aged 6 Months-5 Years - VISION Network, United States, July 2022-June 2023. MMWR Morb Mortal Wkly Rep. 2023 Aug 18; 72(33):886-892.
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