Neurotransmitter Uptake Inhibitors
"Neurotransmitter Uptake Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects.
Descriptor ID |
D014179
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MeSH Number(s) |
D27.505.519.562.437 D27.505.519.625.600 D27.505.696.577.600
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Concept/Terms |
Neurotransmitter Uptake Inhibitors- Neurotransmitter Uptake Inhibitors
- Uptake Inhibitors, Neurotransmitter
- Reuptake Inhibitors, Neurotransmitter
- Inhibitors, Neurotransmitter Reuptake
- Neurotransmitter Reuptake Inhibitors
- Transmitter Uptake Inhibitors, Neuronal
- Inhibitors, Neurotransmitter Uptake
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Below are MeSH descriptors whose meaning is more general than "Neurotransmitter Uptake Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Neurotransmitter Uptake Inhibitors".
This graph shows the total number of publications written about "Neurotransmitter Uptake Inhibitors" by people in this website by year, and whether "Neurotransmitter Uptake Inhibitors" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurotransmitter Uptake Inhibitors" by people in Profiles.
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Brajcich MR, Palau MA, Messer RD, Murphy ME, Marks J. Why the Maternal Medication List Matters: Neonatal Toxicity From Combined Serotonergic Exposures. Pediatrics. 2021 02; 147(2).
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Liem-Moolenaar M, Peeters P, Kamerling IM, Hogg C, Holder G, Kleijn HJ, Spaans E, Udo De Haes J, de Kam ML, Franson KL, Cohen AF, van Gerven JM. Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men. Br J Clin Pharmacol. 2013 Jun; 75(6):1455-67.
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Yager J. Binge eating disorder: the search for better treatments. Am J Psychiatry. 2008 Jan; 165(1):4-6.
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Rice PJ, Abraham ST, Huang NY, Doman RJ. Extraneuronal uptake inhibitor U-0521 decreases contractile responses in rat vas deferens. Gen Pharmacol. 1997 Sep; 29(3):437-9.
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Jikihara H, Ikegami H, Koike K, Wada K, Morishige K, Kurachi H, Hirota K, Miyake A, Tanizawa O. Intraventricular administration of histidyl-proline-diketopiperazine [Cyclo(His-Pro)] suppresses prolactin secretion and synthesis: a possible role of Cyclo(His-Pro) as dopamine uptake blocker in rat hypothalamus. Endocrinology. 1993 Mar; 132(3):953-8.
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