Epitopes
"Epitopes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sites on an antigen that interact with specific antibodies.
Descriptor ID |
D000939
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MeSH Number(s) |
D23.050.550
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Concept/Terms |
Epitopes- Epitopes
- Antigenic Determinants
- Determinants, Antigenic
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Below are MeSH descriptors whose meaning is more general than "Epitopes".
Below are MeSH descriptors whose meaning is more specific than "Epitopes".
This graph shows the total number of publications written about "Epitopes" by people in this website by year, and whether "Epitopes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1993 | 2 | 6 | 8 | 1994 | 1 | 4 | 5 | 1995 | 2 | 2 | 4 | 1996 | 2 | 4 | 6 | 1997 | 1 | 3 | 4 | 1998 | 1 | 5 | 6 | 1999 | 0 | 2 | 2 | 2000 | 0 | 4 | 4 | 2001 | 0 | 1 | 1 | 2002 | 1 | 2 | 3 | 2003 | 0 | 6 | 6 | 2004 | 1 | 6 | 7 | 2005 | 3 | 3 | 6 | 2006 | 3 | 3 | 6 | 2007 | 1 | 3 | 4 | 2008 | 3 | 3 | 6 | 2009 | 3 | 4 | 7 | 2010 | 1 | 10 | 11 | 2011 | 4 | 3 | 7 | 2012 | 2 | 4 | 6 | 2013 | 0 | 5 | 5 | 2014 | 4 | 3 | 7 | 2015 | 4 | 8 | 12 | 2016 | 7 | 3 | 10 | 2017 | 6 | 9 | 15 | 2018 | 3 | 6 | 9 | 2019 | 2 | 9 | 11 | 2020 | 5 | 3 | 8 | 2021 | 5 | 11 | 16 | 2022 | 0 | 6 | 6 | 2023 | 0 | 6 | 6 |
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Below are the most recent publications written about "Epitopes" by people in Profiles.
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Whelan R, Feemster A, Laskowski J, Renner B, Kulik L, Poppelaars F, Lee C, Holers VM, Thurman JM. Female but Not Male Mice Deficient in Soluble IgM Are Susceptible to Chemically Induced Glomerular Injury. J Immunol. 2023 10 15; 211(8):1240-1248.
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Borowska MT, Boughter CT, Bunker JJ, Guthmiller JJ, Wilson PC, Roux B, Bendelac A, Adams EJ. Biochemical and biophysical characterization of natural polyreactivity in antibodies. Cell Rep. 2023 Oct 31; 42(10):113190.
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Owens GP, Fellin TJ, Matschulat A, Salas V, Schaller KL, Given KS, Ritchie AM, Navarro A, Blauth K, Hughes EG, Macklin WB, Bennett JL. Pathogenic myelin-specific antibodies in multiple sclerosis target conformational proteolipid protein 1-anchored membrane domains. J Clin Invest. 2023 10 02; 133(19).
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Wellhausen N, O'Connell RP, Lesch S, Engel NW, Rennels AK, Gonzales D, Herbst F, Young RM, Garcia KC, Weiner D, June CH, Gill SI. Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy. Sci Transl Med. 2023 09 20; 15(714):eadi1145.
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Kulik L, Renner B, Laskowski J, Thurman JM, Michael Holers V. Highly pathogenic natural monoclonal antibody B4-IgM recognizes a post-translational modification comprised of acetylated N-terminal methionine followed by aspartic or glutamic acid. Mol Immunol. 2023 05; 157:112-128.
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Brewer RC, Lanz TV, Hale CR, Sepich-Poore GD, Martino C, Swafford AD, Carroll TS, Kongpachith S, Blum LK, Elliott SE, Blachere NE, Parveen S, Fak J, Yao V, Troyanskaya O, Frank MO, Bloom MS, Jahanbani S, Gomez AM, Iyer R, Ramadoss NS, Sharpe O, Chandrasekaran S, Kelmenson LB, Wang Q, Wong H, Torres HL, Wiesen M, Graves DT, Deane KD, Holers VM, Knight R, Darnell RB, Robinson WH, Orange DE. Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Sci Transl Med. 2023 02 22; 15(684):eabq8476.
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Liu EG, Zhang B, Martin V, Anthonypillai J, Kraft M, Grishin A, Grishina G, Catanzaro JR, Chinthrajah S, Sindher T, Manohar M, Quake AZ, Nadeau K, Burks AW, Kim EH, Kulis MD, Henning AK, Jones SM, Leung DYM, Sicherer SH, Wood RA, Yuan Q, Shreffler W, Sampson H, Shabanova V, Eisenbarth SC. Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens. Sci Transl Med. 2022 11 16; 14(671):eabq0599.
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Wenzlau JM, DiLisio JE, Barbour G, Dang M, Hohenstein AC, Nakayama M, Delong T, Baker RL, Haskins K. Insulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes. Front Immunol. 2022; 13:926650.
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Hoffman HK, Aguilar RS, Clark AR, Groves NS, Pezeshkian N, Bruns MM, van Engelenburg SB. Endocytosed HIV-1 Envelope Glycoprotein Traffics to Rab14+ Late Endosomes and Lysosomes to Regulate Surface Levels in T-Cell Lines. J Virol. 2022 07 27; 96(14):e0076722.
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Bergstedt DT, Tarter WJ, Peterson RA, Feser ML, Parish MC, Striebich CC, Demoruelle MK, Moss L, Bemis EA, Norris JM, Holers VM, Edison JD, Thiele GM, Mikuls TR, Deane KD. Antibodies to Citrullinated Protein Antigens, Rheumatoid Factor Isotypes and the Shared Epitope and the Near-Term Development of Clinically-Apparent Rheumatoid Arthritis. Front Immunol. 2022; 13:916277.
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