 T-Lymphocytes
"T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
| Descriptor ID |
D013601
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| MeSH Number(s) |
A11.118.637.555.567.569 A15.145.229.637.555.567.569 A15.382.490.555.567.569
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| Concept/Terms |
T-Lymphocytes- T-Lymphocytes
- T Lymphocytes
- T-Lymphocyte
- T-Cells
- T Cells
- T-Cell
- Thymus-Dependent Lymphocytes
- Lymphocyte, Thymus-Dependent
- Lymphocytes, Thymus-Dependent
- Thymus Dependent Lymphocytes
- Thymus-Dependent Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes".
This graph shows the total number of publications written about "T-Lymphocytes" by people in this website by year, and whether "T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 26 | 10 | 36 | | 1990 | 19 | 7 | 26 | | 1991 | 18 | 7 | 25 | | 1992 | 14 | 9 | 23 | | 1993 | 17 | 6 | 23 | | 1994 | 16 | 10 | 26 | | 1995 | 5 | 11 | 16 | | 1996 | 14 | 10 | 24 | | 1997 | 22 | 7 | 29 | | 1998 | 23 | 12 | 35 | | 1999 | 23 | 10 | 33 | | 2000 | 24 | 8 | 32 | | 2001 | 25 | 14 | 39 | | 2002 | 26 | 16 | 42 | | 2003 | 17 | 12 | 29 | | 2004 | 25 | 18 | 43 | | 2005 | 27 | 14 | 41 | | 2006 | 24 | 15 | 39 | | 2007 | 17 | 15 | 32 | | 2008 | 22 | 15 | 37 | | 2009 | 24 | 19 | 43 | | 2010 | 16 | 14 | 30 | | 2011 | 12 | 20 | 32 | | 2012 | 18 | 12 | 30 | | 2013 | 30 | 16 | 46 | | 2014 | 14 | 16 | 30 | | 2015 | 16 | 15 | 31 | | 2016 | 12 | 10 | 22 | | 2017 | 18 | 9 | 27 | | 2018 | 4 | 10 | 14 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "T-Lymphocytes" by people in Profiles.
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Mamcarz E, Zhou S, Lockey T, Abdelsamed H, Cross SJ, Kang G, Ma Z, Condori J, Dowdy J, Triplett B, Li C, Maron G, Aldave Becerra JC, Church JA, Dokmeci E, Love JT, da Matta Ain AC, van der Watt H, Tang X, Janssen W, Ryu BY, De Ravin SS, Weiss MJ, Youngblood B, Long-Boyle JR, Gottschalk S, Meagher MM, Malech HL, Puck JM, Cowan MJ, Sorrentino BP. Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. N Engl J Med. 2019 04 18; 380(16):1525-1534.
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Coleman CB, Lang J, Sweet LA, Smith NA, Freed BM, Pan Z, Haverkos B, Pelanda R, Rochford R. Epstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice. J Virol. 2018 11 01; 92(21).
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Zhang W, Jordan KR, Schulte B, Purev E. Characterization of clinical grade CD19 chimeric antigen receptor T cells produced using automated CliniMACS Prodigy system. Drug Des Devel Ther. 2018; 12:3343-3356.
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Ruella M, Xu J, Barrett DM, Fraietta JA, Reich TJ, Ambrose DE, Klichinsky M, Shestova O, Patel PR, Kulikovskaya I, Nazimuddin F, Bhoj VG, Orlando EJ, Fry TJ, Bitter H, Maude SL, Levine BL, Nobles CL, Bushman FD, Young RM, Scholler J, Gill SI, June CH, Grupp SA, Lacey SF, Melenhorst JJ. Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell. Nat Med. 2018 10; 24(10):1499-1503.
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Orlando EJ, Han X, Tribouley C, Wood PA, Leary RJ, Riester M, Levine JE, Qayed M, Grupp SA, Boyer M, De Moerloose B, Nemecek ER, Bittencourt H, Hiramatsu H, Buechner J, Davies SM, Verneris MR, Nguyen K, Brogdon JL, Bitter H, Morrissey M, Pierog P, Pantano S, Engelman JA, Winckler W. Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia. Nat Med. 2018 10; 24(10):1504-1506.
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Graner MW. Extracellular vesicles in cancer immune responses: roles of purinergic receptors. Semin Immunopathol. 2018 09; 40(5):465-475.
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Hughes SM, Ferre AL, Yandura SE, Shetler C, Baker CAR, Calienes F, Levy CN, Astronomo RD, Shu Z, Lentz GM, Fialkow M, Kirby AC, McElrath MJ, Sinclair E, Rohan LC, Anderson PL, Shacklett BL, Dezzutti CS, Gao D, Hladik F. Cryopreservation of human mucosal tissues. PLoS One. 2018; 13(7):e0200653.
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Dinkel BA, Kremer KN, Rollins MR, Medlyn MJ, Hedin KE. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3K?/PREX1 signaling and T cell cytokine secretion. J Biol Chem. 2018 09 07; 293(36):14022-14039.
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Sebio A, Wilky BA, Keedy VL, Jones RL. The current landscape of early drug development for patients with sarcoma in the immunotherapy era. Future Oncol. 2018 May; 14(12):1197-1211.
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Castro G, Merkel PA, Giclas HE, Gibula A, Andersen GE, Corash LM, Lin JS, Green J, Knight V, Stassinopoulos A. Amotosalen/UVA treatment inactivates T cells more effectively than the recommended gamma dose for prevention of transfusion-associated graft-versus-host disease. Transfusion. 2018 06; 58(6):1506-1515.
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