 RNA Stability
"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.
| Descriptor ID |
D020871
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| MeSH Number(s) |
G02.111.780
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| Concept/Terms |
mRNA Degradation- mRNA Degradation
- Degradation, mRNA
- mRNA Transcript Degradation
- Degradation, mRNA Transcript
- Transcript Degradation, mRNA
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Below are MeSH descriptors whose meaning is more general than "RNA Stability".
Below are MeSH descriptors whose meaning is more specific than "RNA Stability".
This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 3 | 4 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 2 | 4 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 4 | 4 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 3 | 1 | 4 | | 2012 | 4 | 4 | 8 | | 2013 | 2 | 1 | 3 | | 2014 | 3 | 3 | 6 | | 2015 | 3 | 4 | 7 | | 2016 | 4 | 4 | 8 | | 2017 | 4 | 2 | 6 | | 2018 | 2 | 3 | 5 | | 2019 | 2 | 0 | 2 | | 2020 | 2 | 2 | 4 | | 2021 | 1 | 3 | 4 | | 2023 | 1 | 2 | 3 |
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Below are the most recent publications written about "RNA Stability" by people in Profiles.
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Huynh TN, Parker R. The PARN, TOE1, and USB1 RNA deadenylases and their roles in non-coding RNA regulation. J Biol Chem. 2023 09; 299(9):105139.
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Briney CA, Rissland OS. Planes, trains, and automobiles: How cells localize their molecules. Mol Cell. 2023 08 03; 83(15):2618-2620.
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Mu?oz O, Lore M, Jagannathan S. The long and short of EJC-independent nonsense-mediated RNA decay. Biochem Soc Trans. 2023 06 28; 51(3):1121-1129.
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Cusic R, Watkins JM, Burke JM. Single-cell analysis of RNase L-mediated mRNA decay. Methods Enzymol. 2023; 692:157-175.
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Siegel DA, Le Tonqueze O, Biton A, Zaitlen N, Erle DJ. Massively parallel analysis of human 3' UTRs reveals that AU-rich element length and registration predict mRNA destabilization. G3 (Bethesda). 2022 01 04; 12(1).
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Li Y, Li J, Wang J, Lynch DR, Shen X, Corey DR, Parekh D, Bhat B, Woo C, Cherry JJ, Napierala JS, Napierala M. Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression. Nucleic Acids Res. 2021 11 18; 49(20):11560-11574.
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Keogh RA, Spencer BL, Sorensen HM, Zapf RL, Briaud P, Bonsall AE, Doran KS, Carroll RK. Global Annotation, Expression Analysis, and Stability of Candidate sRNAs in Group B Streptococcus. mBio. 2021 12 21; 12(6):e0280321.
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Myklebust MP, Thor A, Rosenlund B, Gjengst? P, Karlsdottir ?, Bryd?y M, Bercea BS, Olsen C, Johnson I, Berg MI, Langberg CW, Andreassen KE, Kjellman A, Haugnes HS, Dahl O. Serum miR371 in testicular germ cell cancer before and after orchiectomy, assessed by digital-droplet PCR in a prospective study. Sci Rep. 2021 08 02; 11(1):15582.
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Burke JM, St Clair LA, Perera R, Parker R. SARS-CoV-2 infection triggers widespread host mRNA decay leading to an mRNA export block. RNA. 2021 11; 27(11):1318-1329.
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Dumbovic G, Braunschweig U, Langner HK, Smallegan M, Biayna J, Hass EP, Jastrzebska K, Blencowe B, Cech TR, Caruthers MH, Rinn JL. Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA is driven by intron retention. Nat Commun. 2021 06 03; 12(1):3308.
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