 Transcription Factor AP-2
"Transcription Factor AP-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.
| Descriptor ID |
D050656
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| MeSH Number(s) |
D12.776.260.760 D12.776.930.907
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| Concept/Terms |
Transcription Factor AP-2- Transcription Factor AP-2
- AP-2, Transcription Factor
- Transcription Factor AP 2
- Transcription Factor AP2
- Enhancer-Binding Protein AP-2
- AP-2, Enhancer-Binding Protein
- Enhancer Binding Protein AP 2
- Activator Protein AP-2
- AP-2, Activator Protein
- Activator Protein AP 2
- AP-2 Enhancer Binding Protein
- AP 2 Enhancer Binding Protein
Transcription Factor AP-2 epsilon Protein- Transcription Factor AP-2 epsilon Protein
- Transcription Factor AP 2 epsilon Protein
- Transcription Factor AP-2epsilon
- AP-2epsilon, Transcription Factor
- Transcription Factor AP 2epsilon
- AP-2 epsilon Protein
Transcription Factor AP-2 beta Protein- Transcription Factor AP-2 beta Protein
- Transcription Factor AP 2 beta Protein
- TFAP2B Protein
- Transcription Factor AP-2beta
- AP-2beta, Transcription Factor
- Transcription Factor AP 2beta
- AP-2 beta Protein
- AP 2 beta Protein
Transcription Factor AP-2 delta Protein- Transcription Factor AP-2 delta Protein
- Transcription Factor AP 2 delta Protein
- Transcription Factor Ap-2delta
- Ap-2delta, Transcription Factor
- Transcription Factor Ap 2delta
- AP-2delta Protein
- AP 2delta Protein
Transcription Factor AP-2 gamma Protein- Transcription Factor AP-2 gamma Protein
- Transcription Factor AP 2 gamma Protein
- Transcription Factor AP-2gamma
- AP-2gamma, Transcription Factor
- Transcription Factor AP 2gamma
- AP-2 gamma Protein
- AP 2 gamma Protein
Transcription Factor AP-2 alpha Protein- Transcription Factor AP-2 alpha Protein
- Transcription Factor AP 2 alpha Protein
- AP-2 alpha Protein
- AP 2 alpha Protein
- TFAP2alpha Protein
- Transcription Factor AP-2alpha
- AP-2alpha, Transcription Factor
- Transcription Factor AP 2alpha
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-2".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-2".
This graph shows the total number of publications written about "Transcription Factor AP-2" by people in this website by year, and whether "Transcription Factor AP-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 6 | 6 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 3 | 3 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 4 | 4 | | 2004 | 0 | 6 | 6 | | 2005 | 1 | 0 | 1 | | 2006 | 4 | 0 | 4 | | 2007 | 3 | 1 | 4 | | 2008 | 3 | 0 | 3 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2013 | 2 | 1 | 3 | | 2014 | 2 | 0 | 2 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 2 | 0 | 2 | | 2021 | 4 | 0 | 4 | | 2022 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor AP-2" by people in Profiles.
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Nguyen TT, Mitchell JM, Kiel MD, Kenny CP, Li H, Jones KL, Cornell RA, Williams TJ, Nichols JT, Van Otterloo E. TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway. Development. 2024 Jan 01; 151(1).
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Van Otterloo E, Milanda I, Pike H, Thompson JA, Li H, Jones KL, Williams T. AP-2a and AP-2? cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development. Elife. 2022 03 25; 11.
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Taiyab A, Akula M, Dham J, Deschamps P, Sheardown H, Williams T, Borr?s T, West-Mays JA. Deletion of transcription factor AP-2? from the developing murine trabecular meshwork region leads to progressive glaucomatous changes. J Neurosci Res. 2022 02; 100(2):638-652.
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Walker H, Taiyab A, Deschamps P, Williams T, West-Mays JA. Conditional Deletion of AP-2? in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification. Int J Mol Sci. 2021 Aug 13; 22(16).
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Taiyab A, Saraco A, Akula M, Deschamps P, Ball AK, Williams T, West-Mays JA. Progressive Loss of Retinal Ganglion Cells in Activating Protein-2? Neural Crest Cell Knockout Mice. Curr Eye Res. 2021 10; 46(10):1509-1515.
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Woodruff ED, Gutierrez GC, Van Otterloo E, Williams T, Cohn MJ. Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development. Dev Biol. 2021 04; 472:67-74.
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Gu VW, Cho E, Thompson DT, Cassady VC, Borcherding N, Koch KE, Wu VT, Lorenzen AW, van der Heide DM, White JR, Kulak MV, Williams T, Zhang W, Weigel RJ. AP-2? Is Required for Maintenance of Multipotent Mammary Stem Cells. Stem Cell Reports. 2021 01 12; 16(1):106-119.
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Akula M, Taiyab A, Deschamps P, Yee S, Ball AK, Williams T, West-Mays JA. AP-2? is required for formation of the murine trabecular meshwork and Schlemm's canal. Exp Eye Res. 2020 06; 195:108042.
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Fr?b F, Sock E, Tamm ER, Saur AL, Hillg?rtner S, Williams TJ, Fujii T, Fukunaga R, Wegner M. Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy. Nat Commun. 2019 05 29; 10(1):2361.
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Kousa YA, Zhu H, Fakhouri WD, Lei Y, Kinoshita A, Roushangar RR, Patel NK, Agopian AJ, Yang W, Leslie EJ, Busch TD, Mansour TA, Li X, Smith AL, Li EB, Sharma DB, Williams TJ, Chai Y, Amendt BA, Liao EC, Mitchell LE, Bassuk AG, Gregory S, Ashley-Koch A, Shaw GM, Finnell RH, Schutte BC. The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation. Hum Mol Genet. 2019 05 15; 28(10):1726-1737.
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