 Enzyme Activation
"Enzyme Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
| Descriptor ID |
D004789
|
| MeSH Number(s) |
G02.111.263 G03.328
|
| Concept/Terms |
Enzyme Activation- Enzyme Activation
- Activation, Enzyme
- Activations, Enzyme
- Enzyme Activations
|
Below are MeSH descriptors whose meaning is more general than "Enzyme Activation".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Activation".
This graph shows the total number of publications written about "Enzyme Activation" by people in this website by year, and whether "Enzyme Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 0 | 6 | 6 | | 1990 | 0 | 11 | 11 | | 1991 | 0 | 12 | 12 | | 1992 | 0 | 9 | 9 | | 1993 | 0 | 10 | 10 | | 1994 | 0 | 18 | 18 | | 1995 | 0 | 18 | 18 | | 1996 | 0 | 27 | 27 | | 1997 | 0 | 27 | 27 | | 1998 | 0 | 21 | 21 | | 1999 | 0 | 31 | 31 | | 2000 | 0 | 23 | 23 | | 2001 | 0 | 34 | 34 | | 2002 | 0 | 39 | 39 | | 2003 | 0 | 38 | 38 | | 2004 | 2 | 31 | 33 | | 2005 | 1 | 31 | 32 | | 2006 | 0 | 32 | 32 | | 2007 | 0 | 29 | 29 | | 2008 | 0 | 35 | 35 | | 2009 | 0 | 29 | 29 | | 2010 | 1 | 30 | 31 | | 2011 | 1 | 17 | 18 | | 2012 | 1 | 22 | 23 | | 2013 | 0 | 20 | 20 | | 2014 | 1 | 19 | 20 | | 2015 | 0 | 22 | 22 | | 2016 | 0 | 7 | 7 | | 2017 | 0 | 16 | 16 | | 2018 | 0 | 3 | 3 | | 2019 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Enzyme Activation" by people in Profiles.
-
Zhang Y, Klein BJ, Cox KL, Bertulat B, Tencer AH, Holden MR, Wright GM, Black J, Cardoso MC, Poirier MG, Kutateladze TG. Mechanism for autoinhibition and activation of the MORC3 ATPase. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):6111-6119.
-
Sanchez-Lozada LG, Andres-Hernando A, Garcia-Arroyo FE, Cicerchi C, Li N, Kuwabara M, Roncal-Jimenez CA, Johnson RJ, Lanaspa MA. Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats. J Biol Chem. 2019 03 15; 294(11):4272-4281.
-
Kim JS, Liu L, Fitzsimmons LF, Wang Y, Crawford MA, Mastrogiovanni M, Trujillo M, Till JKA, Radi R, Dai S, Vázquez-Torres A. DksA-DnaJ redox interactions provide a signal for the activation of bacterial RNA polymerase. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11780-E11789.
-
Rangarajan S, Bone NB, Zmijewska AA, Jiang S, Park DW, Bernard K, Locy ML, Ravi S, Deshane J, Mannon RB, Abraham E, Darley-Usmar V, Thannickal VJ, Zmijewski JW. Metformin reverses established lung fibrosis in a bleomycin model. Nat Med. 2018 08; 24(8):1121-1127.
-
Greaves SA, Peterson JN, Torres RM, Pelanda R. Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Front Immunol. 2018; 9:707.
-
Buckles TC, Ziemba BP, Masson GR, Williams RL, Falke JJ. Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Ka and PIP3 Signaling. Biophys J. 2017 Dec 05; 113(11):2396-2405.
-
Karoor V, Fini MA, Loomis Z, Sullivan T, Hersh LB, Gerasimovskaya E, Irwin D, Dempsey EC. Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice. Arterioscler Thromb Vasc Biol. 2018 01; 38(1):154-163.
-
Copley SD. Shining a light on enzyme promiscuity. Curr Opin Struct Biol. 2017 12; 47:167-175.
-
Kumar R, Deep G, Wempe MF, Surek J, Kumar A, Agarwal R, Agarwal C. Procyanidin B2 3,3?-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK. Mol Carcinog. 2018 Jan; 57(1):57-69.
-
Bammert TD, Hijmans JG, Reiakvam WR, Levy MV, Brewster LM, Goldthwaite ZA, Greiner JJ, Stockelman KA, DeSouza CA. High glucose derived endothelial microparticles increase active caspase-3 and reduce microRNA-Let-7a expression in endothelial cells. Biochem Biophys Res Commun. 2017 11 18; 493(2):1026-1029.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|