 Enzyme Activation
"Enzyme Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
| Descriptor ID |
D004789
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| MeSH Number(s) |
G02.111.263 G03.328
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| Concept/Terms |
Enzyme Activation- Enzyme Activation
- Activation, Enzyme
- Activations, Enzyme
- Enzyme Activations
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Below are MeSH descriptors whose meaning is more general than "Enzyme Activation".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Activation".
This graph shows the total number of publications written about "Enzyme Activation" by people in this website by year, and whether "Enzyme Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 11 | 11 | | 1992 | 0 | 8 | 8 | | 1993 | 0 | 9 | 9 | | 1994 | 0 | 13 | 13 | | 1995 | 0 | 12 | 12 | | 1996 | 0 | 25 | 25 | | 1997 | 0 | 19 | 19 | | 1998 | 0 | 22 | 22 | | 1999 | 0 | 27 | 27 | | 2000 | 0 | 22 | 22 | | 2001 | 0 | 30 | 30 | | 2002 | 0 | 37 | 37 | | 2003 | 0 | 33 | 33 | | 2004 | 2 | 35 | 37 | | 2005 | 1 | 31 | 32 | | 2006 | 0 | 38 | 38 | | 2007 | 0 | 30 | 30 | | 2008 | 0 | 33 | 33 | | 2009 | 0 | 27 | 27 | | 2010 | 1 | 28 | 29 | | 2011 | 1 | 19 | 20 | | 2012 | 3 | 24 | 27 | | 2013 | 0 | 23 | 23 | | 2014 | 1 | 17 | 18 | | 2015 | 0 | 19 | 19 | | 2016 | 0 | 9 | 9 | | 2017 | 0 | 17 | 17 | | 2018 | 0 | 3 | 3 | | 2019 | 0 | 8 | 8 | | 2020 | 0 | 11 | 11 |
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Below are the most recent publications written about "Enzyme Activation" by people in Profiles.
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Rimel JK, Poss ZC, Erickson B, Maas ZL, Ebmeier CC, Johnson JL, Decker TM, Yaron TM, Bradley MJ, Hamman KB, Hu S, Malojcic G, Marineau JJ, White PW, Brault M, Tao L, DeRoy P, Clavette C, Nayak S, Damon LJ, Kaltheuner IH, Bunch H, Cantley LC, Geyer M, Iwasa J, Dowell RD, Bentley DL, Old WM, Taatjes DJ. Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription. Genes Dev. 2020 11 01; 34(21-22):1452-1473.
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Iverson DB, Xiao Y, Jones DN, Eisenmesser EZ, Ahn NG. Activation Loop Dynamics Are Coupled to Core Motions in Extracellular Signal-Regulated Kinase-2. Biochemistry. 2020 07 28; 59(29):2698-2706.
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Wang Q, Notay K, Downey GP, McCulloch CA. The Leucine-Rich Repeat Region of CARMIL1 Regulates IL-1-Mediated ERK Activation, MMP Expression, and Collagen Degradation. Cell Rep. 2020 06 30; 31(13):107781.
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Wang M, Strand MJ, Lanser BJ, Santos C, Bendelja K, Fish J, Esterl EA, Ashino S, Abbott JK, Knight V, Gelfand EW. Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children. PLoS One. 2020; 15(6):e0233563.
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Sayama S, Song A, Brown BC, Couturier J, Cai X, Xu P, Chen C, Zheng Y, Iriyama T, Sibai B, Longo M, Kellems RE, D'Alessandro A, Xia Y. Maternal erythrocyte ENT1-mediated AMPK activation counteracts placental hypoxia and supports fetal growth. JCI Insight. 2020 05 21; 5(10).
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Dabo AJ, Ezegbunam W, Wyman AE, Moon J, Railwah C, Lora A, Majka SM, Geraghty P, Foronjy RF. Targeting c-Src Reverses Accelerated GPX-1 mRNA Decay in Chronic Obstructive Pulmonary Disease Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2020 05; 62(5):598-607.
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De Dominici M, Porazzi P, Xiao Y, Chao A, Tang HY, Kumar G, Fortina P, Spinelli O, Rambaldi A, Peterson LF, Petruk S, Barletta C, Mazo A, Cingolani G, Salvino JM, Calabretta B. Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs. Blood. 2020 04 30; 135(18):1560-1573.
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Anwar A, Anwar H, Yamauchi T, Tseng R, Agarwal R, Horwitz LD, Zhai Z, Fujita M. Bucillamine Inhibits UVB-Induced MAPK Activation and Apoptosis in Human HaCaT Keratinocytes and SKH-1 Hairless Mouse Skin. Photochem Photobiol. 2020 07; 96(4):870-876.
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Schier AC, Taatjes DJ. Structure and mechanism of the RNA polymerase II transcription machinery. Genes Dev. 2020 04 01; 34(7-8):465-488.
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Deep G, Jain A, Kumar A, Agarwal C, Kim S, Leevy WM, Agarwal R. Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches. Mol Carcinog. 2020 03; 59(3):323-332.
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