 Cell Polarity
"Cell Polarity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Orientation of intracellular structures especially with respect to the apical and basolateral domains of the plasma membrane. Polarized cells must direct proteins from the Golgi apparatus to the appropriate domain since tight junctions prevent proteins from diffusing between the two domains.
| Descriptor ID |
D016764
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| MeSH Number(s) |
G04.250
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| Concept/Terms |
Cell Polarity- Cell Polarity
- Cell Polarities
- Polarities, Cell
- Polarity, Cell
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Below are MeSH descriptors whose meaning is more general than "Cell Polarity".
Below are MeSH descriptors whose meaning is more specific than "Cell Polarity".
This graph shows the total number of publications written about "Cell Polarity" by people in this website by year, and whether "Cell Polarity" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 2 | 2 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 4 | 4 | | 1995 | 1 | 2 | 3 | | 1997 | 2 | 4 | 6 | | 1998 | 0 | 5 | 5 | | 1999 | 3 | 1 | 4 | | 2000 | 0 | 3 | 3 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 3 | 3 | 6 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 4 | 4 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 4 | 5 | | 2008 | 3 | 5 | 8 | | 2009 | 3 | 5 | 8 | | 2010 | 2 | 2 | 4 | | 2011 | 4 | 2 | 6 | | 2012 | 2 | 2 | 4 | | 2013 | 1 | 5 | 6 | | 2014 | 1 | 5 | 6 | | 2015 | 5 | 4 | 9 | | 2016 | 3 | 3 | 6 | | 2017 | 1 | 3 | 4 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 2 | 3 | | 2020 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Cell Polarity" by people in Profiles.
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Buckles TC, Ziemba BP, Djukovic D, Falke JJ. Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating. PLoS One. 2020; 15(5):e0233012.
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Vladar EK, Königshoff M. Noncanonical Wnt planar cell polarity signaling in lung development and disease. Biochem Soc Trans. 2020 02 28; 48(1):231-243.
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Peterman E, Prekeris R. The postmitotic midbody: Regulating polarity, stemness, and proliferation. J Cell Biol. 2019 12 02; 218(12):3903-3911.
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Jeong J, Kim W, Hens J, Dann P, Schedin P, Friedman PA, Wysolmerski JJ. NHERF1 Is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland. Endocrinology. 2019 08 01; 160(8):1797-1810.
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Smith P, Godde N, Rubio S, Tekeste M, Vladar EK, Axelrod JD, Henderson DJ, Milgrom-Hoffman M, Humbert PO, Hinck L. VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland. Sci Rep. 2019 05 08; 9(1):7079.
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Merks AM, Swinarski M, Meyer AM, Müller NV, Özcan I, Donat S, Burger A, Gilbert S, Mosimann C, Abdelilah-Seyfried S, Panáková D. Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity. Nat Commun. 2018 06 04; 9(1):2161.
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Kunimoto K, Bayly RD, Vladar EK, Vonderfecht T, Gallagher AR, Axelrod JD. Disruption of Core Planar Cell Polarity Signaling Regulates Renal Tubule Morphogenesis but Is Not Cystogenic. Curr Biol. 2017 Oct 23; 27(20):3120-3131.e4.
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Zhou Q, Dai J, Chen T, Dada LA, Zhang X, Zhang W, DeCamp MM, Winn RA, Sznajder JI, Zhou G. Downregulation of PKC?/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion. Cell Signal. 2017 10; 38:49-59.
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Chao JR, Knight K, Engel AL, Jankowski C, Wang Y, Manson MA, Gu H, Djukovic D, Raftery D, Hurley JB, Du J. Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side. J Biol Chem. 2017 08 04; 292(31):12895-12905.
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Connacher MK, Tay JW, Ahn NG. Rear-polarized Wnt5a-receptor-actin-myosin-polarity (WRAMP) structures promote the speed and persistence of directional cell migration. Mol Biol Cell. 2017 Jul 07; 28(14):1924-1936.
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