 Cell Polarity
"Cell Polarity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Orientation of intracellular structures especially with respect to the apical and basolateral domains of the plasma membrane. Polarized cells must direct proteins from the Golgi apparatus to the appropriate domain since tight junctions prevent proteins from diffusing between the two domains.
| Descriptor ID |
D016764
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| MeSH Number(s) |
G04.250
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| Concept/Terms |
Cell Polarity- Cell Polarity
- Cell Polarities
- Polarities, Cell
- Polarity, Cell
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Below are MeSH descriptors whose meaning is more general than "Cell Polarity".
Below are MeSH descriptors whose meaning is more specific than "Cell Polarity".
This graph shows the total number of publications written about "Cell Polarity" by people in this website by year, and whether "Cell Polarity" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 2 | 2 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 4 | 4 | | 1995 | 1 | 2 | 3 | | 1997 | 2 | 4 | 6 | | 1998 | 0 | 5 | 5 | | 1999 | 3 | 1 | 4 | | 2000 | 1 | 3 | 4 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 3 | 4 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 4 | 4 | | 2006 | 1 | 2 | 3 | | 2007 | 2 | 5 | 7 | | 2008 | 3 | 5 | 8 | | 2009 | 4 | 4 | 8 | | 2010 | 1 | 3 | 4 | | 2011 | 4 | 2 | 6 | | 2012 | 2 | 3 | 5 | | 2013 | 1 | 4 | 5 | | 2014 | 2 | 6 | 8 | | 2015 | 4 | 3 | 7 | | 2016 | 2 | 3 | 5 | | 2017 | 2 | 2 | 4 |
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Below are the most recent publications written about "Cell Polarity" by people in Profiles.
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Kunimoto K, Bayly RD, Vladar EK, Vonderfecht T, Gallagher AR, Axelrod JD. Disruption of Core Planar Cell Polarity Signaling Regulates Renal Tubule Morphogenesis but Is Not Cystogenic. Curr Biol. 2017 Oct 23; 27(20):3120-3131.e4.
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Zhou Q, Dai J, Chen T, Dada LA, Zhang X, Zhang W, DeCamp MM, Winn RA, Sznajder JI, Zhou G. Downregulation of PKC?/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion. Cell Signal. 2017 10; 38:49-59.
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Connacher MK, Tay JW, Ahn NG. Rear-polarized Wnt5a-receptor-actin-myosin-polarity (WRAMP) structures promote the speed and persistence of directional cell migration. Mol Biol Cell. 2017 Jul 07; 28(14):1924-1936.
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Gibieža P, Prekeris R. Rab GTPases and cell division. Small GTPases. 2018 03 04; 9(1-2):107-115.
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Poobalasingam T, Yates LL, Walker SA, Pereira M, Gross NY, Ali A, Kolatsi-Joannou M, Jarvelin MR, Pekkanen J, Papakrivopoulou E, Long DA, Griffiths M, Wagner D, Königshoff M, Hind M, Minelli C, Lloyd CM, Dean CH. Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair. Dis Model Mech. 2017 04 01; 10(4):409-423.
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Yoon J, Leyva-Castillo JM, Wang G, Galand C, Oyoshi MK, Kumar L, Hoff S, He R, Chervonsky A, Oppenheim JJ, Kuchroo VK, van den Brink MR, Malefyt Rde W, Tessier PA, Fuhlbrigge R, Rosenstiel P, Terhorst C, Murphy G, Geha RS. IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization. J Exp Med. 2016 09 19; 213(10):2147-66.
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Mangan AJ, Sietsema DV, Li D, Moore JK, Citi S, Prekeris R. Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells. Nat Commun. 2016 08 03; 7:12426.
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Hudish LI, Galati DF, Ravanelli AM, Pearson CG, Huang P, Appel B. miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development. 2016 07 01; 143(13):2292-304.
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Peterman E, Prekeris R. Understanding post-mitotic roles of the midbody during cell differentiation and polarization. Methods Cell Biol. 2017; 137:173-186.
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Chen S, Kammerl IE, Vosyka O, Baumann T, Yu Y, Wu Y, Irmler M, Overkleeft HS, Beckers J, Eickelberg O, Meiners S, Stoeger T. Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages. Cell Death Differ. 2016 06; 23(6):1026-37.
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