 Lens, Crystalline
"Lens, Crystalline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.
| Descriptor ID |
D007908
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| MeSH Number(s) |
A09.371.060.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lens, Crystalline".
Below are MeSH descriptors whose meaning is more specific than "Lens, Crystalline".
This graph shows the total number of publications written about "Lens, Crystalline" by people in this website by year, and whether "Lens, Crystalline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 2 | 1 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 3 | 1 | 4 | | 2000 | 1 | 2 | 3 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 0 | 2 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 1 | 3 | 4 | | 2007 | 4 | 0 | 4 | | 2008 | 2 | 1 | 3 | | 2009 | 3 | 0 | 3 | | 2011 | 3 | 0 | 3 | | 2012 | 3 | 1 | 4 | | 2013 | 2 | 0 | 2 | | 2014 | 2 | 1 | 3 | | 2015 | 2 | 2 | 4 | | 2016 | 3 | 2 | 5 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 1 | 3 | | 2019 | 3 | 0 | 3 | | 2020 | 2 | 0 | 2 | | 2021 | 2 | 0 | 2 | | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lens, Crystalline" by people in Profiles.
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Thompson B, Davidson EA, Chen Y, Orlicky DJ, Thompson DC, Vasiliou V. Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues. Chem Biol Interact. 2022 Mar 01; 355:109804.
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Thompson B, Chen Y, Davidson EA, Garcia-Milian R, Golla JP, Apostolopoulos N, Orlicky DJ, Schey K, Thompson DC, Vasiliou V. Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function. Ocul Surf. 2021 10; 22:190-203.
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Nam MH, Pantcheva MB, Rankenberg J, Nagaraj RH. Transforming growth factor-ß2-mediated mesenchymal transition in lens epithelial cells is repressed in the absence of RAGE. Biochem J. 2021 06 25; 478(12):2285-2296.
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Patnaik JL, Kahook MY. Long-term follow-up and clinical evaluation of the light-adjustable intraocular lens implanted after cataract removal: 7-year results. J Cataract Refract Surg. 2020 06; 46(6):929.
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Nandi SK, Nahomi RB, Rankenberg J, Glomb MA, Nagaraj RH. Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of a-crystallin: Implications for lens aging and presbyopia. J Biol Chem. 2020 04 24; 295(17):5701-5716.
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Nahomi RB, Nandi SK, Rakete S, Michel C, Fritz KS, Nagaraj RH. Lysine malonylation and propionylation are prevalent in human lens proteins. Exp Eye Res. 2020 01; 190:107864.
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Zukin LM, Pedler MG, Chyung K, Seiwald S, Lenhart P, Shieh B, Petrash JM. Aldose reductase inhibition enhances lens regeneration in mice. Chem Biol Interact. 2019 Jul 01; 307:58-62.
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Nandi SK, Rakete S, Nahomi RB, Michel C, Dunbar A, Fritz KS, Nagaraj RH. Succinylation Is a Gain-of-Function Modification in Human Lens aB-Crystallin. Biochemistry. 2019 03 05; 58(9):1260-1274.
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Nahomi RB, Nagaraj RH. The role of HIF-1a in the TGF-ß2-mediated epithelial-to-mesenchymal transition of human lens epithelial cells. J Cell Biochem. 2018 08; 119(8):6814-6827.
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Nam MH, Nagaraj RH. Matrix-bound AGEs enhance TGFß2-mediated mesenchymal transition of lens epithelial cells via the noncanonical pathway: implications for secondary cataract formation. Biochem J. 2018 04 23; 475(8):1427-1440.
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