 Lens, Crystalline
"Lens, Crystalline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.
| Descriptor ID |
D007908
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| MeSH Number(s) |
A09.371.060.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lens, Crystalline".
Below are MeSH descriptors whose meaning is more specific than "Lens, Crystalline".
This graph shows the total number of publications written about "Lens, Crystalline" by people in this website by year, and whether "Lens, Crystalline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 2 | 0 | 2 | | 1992 | 0 | 1 | 1 | | 1995 | 1 | 2 | 3 | | 1996 | 2 | 1 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 3 | 1 | 4 | | 2000 | 1 | 3 | 4 | | 2001 | 2 | 0 | 2 | | 2002 | 2 | 1 | 3 | | 2003 | 0 | 3 | 3 | | 2004 | 2 | 1 | 3 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 3 | 4 | | 2007 | 6 | 1 | 7 | | 2008 | 3 | 4 | 7 | | 2009 | 4 | 1 | 5 | | 2010 | 5 | 0 | 5 | | 2011 | 7 | 0 | 7 | | 2012 | 4 | 1 | 5 | | 2013 | 4 | 0 | 4 | | 2014 | 3 | 1 | 4 | | 2015 | 3 | 2 | 5 | | 2016 | 3 | 2 | 5 | | 2017 | 1 | 1 | 2 | | 2018 | 3 | 1 | 4 | | 2019 | 4 | 0 | 4 | | 2020 | 2 | 0 | 2 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lens, Crystalline" by people in Profiles.
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Hupy ML, Pedler MG, Shieh B, Wang D, Wang XJ, Petrash JM. Suppression of epithelial to mesenchymal transition markers in mouse lens by a Smad7-based recombinant protein. Chem Biol Interact. 2021 Aug 01; 344:109495.
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Patnaik JL, Kahook MY. Long-term follow-up and clinical evaluation of the light-adjustable intraocular lens implanted after cataract removal: 7-year results. J Cataract Refract Surg. 2020 06; 46(6):929.
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Nandi SK, Nahomi RB, Rankenberg J, Glomb MA, Nagaraj RH. Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of a-crystallin: Implications for lens aging and presbyopia. J Biol Chem. 2020 04 24; 295(17):5701-5716.
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Nahomi RB, Nandi SK, Rakete S, Michel C, Fritz KS, Nagaraj RH. Lysine malonylation and propionylation are prevalent in human lens proteins. Exp Eye Res. 2020 01; 190:107864.
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Zukin LM, Pedler MG, Chyung K, Seiwald S, Lenhart P, Shieh B, Petrash JM. Aldose reductase inhibition enhances lens regeneration in mice. Chem Biol Interact. 2019 Jul 01; 307:58-62.
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Nandi SK, Nahomi RB, Harris PS, Michel CR, Fritz KS, Nagaraj RH. The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of a-crystallin in mouse lenses. Exp Eye Res. 2019 05; 182:1-9.
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Nandi SK, Rakete S, Nahomi RB, Michel C, Dunbar A, Fritz KS, Nagaraj RH. Succinylation Is a Gain-of-Function Modification in Human Lens aB-Crystallin. Biochemistry. 2019 03 05; 58(9):1260-1274.
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Zukin LM, Pedler MG, Groman-Lupa S, Pantcheva M, Ammar DA, Petrash JM. Aldose Reductase Inhibition Prevents Development of Posterior Capsular Opacification in an In Vivo Model of Cataract Surgery. Invest Ophthalmol Vis Sci. 2018 07 02; 59(8):3591-3598.
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Nahomi RB, Nagaraj RH. The role of HIF-1a in the TGF-ß2-mediated epithelial-to-mesenchymal transition of human lens epithelial cells. J Cell Biochem. 2018 08; 119(8):6814-6827.
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Nam MH, Nagaraj RH. Matrix-bound AGEs enhance TGFß2-mediated mesenchymal transition of lens epithelial cells via the noncanonical pathway: implications for secondary cataract formation. Biochem J. 2018 04 23; 475(8):1427-1440.
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