 Lens, Crystalline
"Lens, Crystalline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.
| Descriptor ID |
D007908
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| MeSH Number(s) |
A09.371.060.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lens, Crystalline".
Below are MeSH descriptors whose meaning is more specific than "Lens, Crystalline".
This graph shows the total number of publications written about "Lens, Crystalline" by people in this website by year, and whether "Lens, Crystalline" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 2 | 1 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 3 | 1 | 4 | | 2000 | 1 | 3 | 4 | | 2001 | 2 | 0 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2004 | 2 | 1 | 3 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 3 | 4 | | 2007 | 5 | 1 | 6 | | 2008 | 3 | 3 | 6 | | 2009 | 4 | 1 | 5 | | 2010 | 2 | 0 | 2 | | 2011 | 5 | 0 | 5 | | 2012 | 4 | 1 | 5 | | 2013 | 3 | 0 | 3 | | 2014 | 3 | 1 | 4 | | 2015 | 3 | 2 | 5 | | 2016 | 3 | 2 | 5 | | 2017 | 1 | 1 | 2 | | 2018 | 3 | 1 | 4 | | 2019 | 4 | 0 | 4 | | 2020 | 3 | 0 | 3 | | 2021 | 3 | 1 | 4 | | 2022 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Lens, Crystalline" by people in Profiles.
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Panja S, Nahomi RB, Rankenberg J, Michel CR, Gaikwad H, Nam MH, Nagaraj RH. Aggrelyte-2 promotes protein solubility and decreases lens stiffness through lysine acetylation and disulfide reduction: Implications for treating presbyopia. Aging Cell. 2023 04; 22(4):e13797.
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Panja S, Gaikwad H, Rankenberg J, Nam MH, Nagaraj RH. Promotion of Protein Solubility and Reduction in Stiffness in Human Lenses by Aggrelyte-1: Implications for Reversing Presbyopia. Int J Mol Sci. 2023 Jan 22; 24(3).
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Thompson B, Davidson EA, Chen Y, Orlicky DJ, Thompson DC, Vasiliou V. Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues. Chem Biol Interact. 2022 Mar 01; 355:109804.
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Thompson B, Chen Y, Davidson EA, Garcia-Milian R, Golla JP, Apostolopoulos N, Orlicky DJ, Schey K, Thompson DC, Vasiliou V. Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function. Ocul Surf. 2021 10; 22:190-203.
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Gautam D, Pedler MG, Nair DP, Petrash JM. Nanogel-Facilitated In-Situ Delivery of a Cataract Inhibitor. Biomolecules. 2021 08 04; 11(8).
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Nam MH, Pantcheva MB, Rankenberg J, Nagaraj RH. Transforming growth factor-?2-mediated mesenchymal transition in lens epithelial cells is repressed in the absence of RAGE. Biochem J. 2021 06 25; 478(12):2285-2296.
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Hupy ML, Pedler MG, Shieh B, Wang D, Wang XJ, Petrash JM. Suppression of epithelial to mesenchymal transition markers in mouse lens by a Smad7-based recombinant protein. Chem Biol Interact. 2021 Aug 01; 344:109495.
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Nandi SK, Rankenberg J, Rakete S, Nahomi RB, Glomb MA, Linetsky MD, Nagaraj RH. Glycation-mediated protein crosslinking and stiffening in mouse lenses are inhibited by carboxitin in vitro. Glycoconj J. 2021 06; 38(3):347-359.
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Patnaik JL, Kahook MY. Long-term follow-up and clinical evaluation of the light-adjustable intraocular lens implanted after cataract removal: 7-year results. J Cataract Refract Surg. 2020 06; 46(6):929.
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Nandi SK, Nahomi RB, Rankenberg J, Glomb MA, Nagaraj RH. Glycation-mediated inter-protein cross-linking is promoted by chaperone-client complexes of a-crystallin: Implications for lens aging and presbyopia. J Biol Chem. 2020 04 24; 295(17):5701-5716.
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