Genes, ras
"Genes, ras" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (ras) originally isolated from Harvey (H-ras, Ha-ras, rasH) and Kirsten (K-ras, Ki-ras, rasK) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both H-ras and K-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related N-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein.
Descriptor ID |
D011905
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MeSH Number(s) |
G05.360.340.024.340.375.500.791.550
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Concept/Terms |
N-ras Genes- N-ras Genes
- Genes, N-ras
- N ras Genes
- N-ras Gene
- N-ras Oncogenes
- N ras Oncogenes
- N-ras Oncogene
v-Ha-ras Genes- v-Ha-ras Genes
- Gene, v-Ha-ras
- Genes, v-Ha-ras
- v Ha ras Genes
- v-Ha-ras Gene
v-Ki-ras Genes- v-Ki-ras Genes
- Gene, v-Ki-ras
- Genes, v-Ki-ras
- v Ki ras Genes
- v-Ki-ras Gene
Ha-ras Genes- Ha-ras Genes
- Gene, Ha-ras
- Genes, Ha-ras
- Ha ras Genes
- Ha-ras Gene
Ki-ras Genes- Ki-ras Genes
- Gene, Ki-ras
- Genes, Ki-ras
- Ki ras Genes
- Ki-ras Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, ras".
Below are MeSH descriptors whose meaning is more specific than "Genes, ras".
This graph shows the total number of publications written about "Genes, ras" by people in this website by year, and whether "Genes, ras" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 4 | 4 | 1995 | 4 | 3 | 7 | 1996 | 1 | 2 | 3 | 1997 | 2 | 3 | 5 | 1998 | 2 | 1 | 3 | 1999 | 1 | 1 | 2 | 2000 | 5 | 0 | 5 | 2001 | 1 | 1 | 2 | 2002 | 1 | 0 | 1 | 2004 | 2 | 0 | 2 | 2006 | 1 | 1 | 2 | 2007 | 1 | 1 | 2 | 2008 | 3 | 0 | 3 | 2009 | 1 | 2 | 3 | 2010 | 1 | 2 | 3 | 2011 | 2 | 0 | 2 | 2012 | 0 | 3 | 3 | 2013 | 1 | 1 | 2 | 2015 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 | 2018 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 | 2020 | 0 | 1 | 1 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, ras" by people in Profiles.
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Zhong H, Lu W, Tang Y, Wiel C, Wei Y, Cao J, Riedlinger G, Papagiannakopoulos T, Guo JY, Bergo MO, Kang Y, Ganesan S, Sabaawy HE, Pine SR. SOX9 drives KRAS-induced lung adenocarcinoma progression and suppresses anti-tumor immunity. Oncogene. 2023 Jun; 42(27):2183-2194.
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Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. p21 produces a bioactive secretome that places stressed cells under immunosurveillance. Science. 2021 Oct 29; 374(6567):eabb3420.
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Setty BA, Jinesh GG, Arnold M, Pettersson F, Cheng CH, Cen L, Yoder SJ, Teer JK, Flores ER, Reed DR, Brohl AS. The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss. PLoS Genet. 2020 04; 16(4):e1008642.
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Shi C, Pan FC, Kim JN, Washington MK, Padmanabhan C, Meyer CT, Kopp JL, Sander M, Gannon M, Beauchamp RD, Wright CV, Means AL. Differential Cell Susceptibilities to KrasG12D in the Setting of Obstructive Chronic Pancreatitis. Cell Mol Gastroenterol Hepatol. 2019; 8(4):579-594.
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McCallen LM, Ameduri RK, Denfield SW, Dodd DA, Everitt MD, Johnson JN, Lee TM, Lin AE, Lohr JL, May LJ, Pierpont ME, Stevenson DA, Chatfield KC. Cardiac transplantation in children with Noonan syndrome. Pediatr Transplant. 2019 09; 23(6):e13535.
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Krishnamurthy A, Dasari A, Noonan AM, Mehnert JM, Lockhart AC, Leong S, Capasso A, Stein MN, Sanoff HK, Lee JJ, Hansen A, Malhotra U, Rippke S, Gustafson DL, Pitts TM, Ellison K, Davis SL, Messersmith WA, Eckhardt SG, Lieu CH. Phase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer. Cancer Res. 2018 09 15; 78(18):5398-5407.
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Sperduto PW, Jiang W, Brown PD, Braunstein S, Sneed P, Wattson DA, Shih HA, Bangdiwala A, Shanley R, Lockney NA, Beal K, Lou E, Amatruda T, Sperduto WA, Kirkpatrick JP, Yeh N, Gaspar LE, Molitoris JK, Masucci L, Roberge D, Yu J, Chiang V, Mehta M. The Prognostic Value of BRAF, C-KIT, and NRAS Mutations in Melanoma Patients With Brain Metastases. Int J Radiat Oncol Biol Phys. 2017 08 01; 98(5):1069-1077.
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Beadnell TC, Mishall KM, Zhou Q, Riffert SM, Wuensch KE, Kessler BE, Corpuz ML, Jing X, Kim J, Wang G, Tan AC, Schweppe RE. The Mitogen-Activated Protein Kinase Pathway Facilitates Resistance to the Src Inhibitor Dasatinib in Thyroid Cancer. Mol Cancer Ther. 2016 08; 15(8):1952-63.
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Danis E, Yamauchi T, Echanique K, Zhang X, Haladyna JN, Riedel SS, Zhu N, Xie H, Orkin SH, Armstrong SA, Bernt KM, Neff T. Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia. Cell Rep. 2016 Mar 01; 14(8):1953-65.
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Sholl LM, Aisner DL, Varella-Garcia M, Berry LD, Dias-Santagata D, Wistuba II, Chen H, Fujimoto J, Kugler K, Franklin WA, Iafrate AJ, Ladanyi M, Kris MG, Johnson BE, Bunn PA, Minna JD, Kwiatkowski DJ. Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience. J Thorac Oncol. 2015 May; 10(5):768-777.
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