 Tryptophan
"Tryptophan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.
| Descriptor ID |
D014364
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| MeSH Number(s) |
D12.125.072.050.850 D12.125.142.875
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| Concept/Terms |
Tryptophan- Tryptophan
- L-Tryptophan
- L Tryptophan
- Levotryptophan
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Below are MeSH descriptors whose meaning is more general than "Tryptophan".
Below are MeSH descriptors whose meaning is more specific than "Tryptophan".
This graph shows the total number of publications written about "Tryptophan" by people in this website by year, and whether "Tryptophan" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 2 | 3 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 7 | 7 | | 2006 | 4 | 5 | 9 | | 2007 | 0 | 2 | 2 | | 2008 | 1 | 2 | 3 | | 2009 | 0 | 3 | 3 | | 2010 | 1 | 3 | 4 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 4 | 4 | | 2014 | 2 | 1 | 3 | | 2015 | 0 | 1 | 1 | | 2016 | 3 | 0 | 3 | | 2017 | 4 | 1 | 5 | | 2018 | 2 | 1 | 3 | | 2019 | 0 | 1 | 1 | | 2020 | 2 | 4 | 6 | | 2021 | 1 | 3 | 4 | | 2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Tryptophan" by people in Profiles.
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Davidson JA, Robison J, Khailova L, Frank BS, Jaggers J, Ing RJ, Lawson S, Iguidbashian J, Ali E, Treece A, Soranno DE, Osorio-Lujan S, Klawitter J. Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury. Am J Physiol Renal Physiol. 2022 07 01; 323(1):F20-F32.
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Melena I, Piani F, Tommerdahl KL, Severn C, Chung LT, MacDonald A, Vinovskis C, Cherney D, Pyle L, Roncal-Jimenez CA, Lanaspa MA, Rewers A, van Raalte DH, Cara-Fuentes G, Parikh CR, Nelson RG, Pavkov ME, Nadeau KJ, Johnson RJ, Bjornstad P. Aminoaciduria and metabolic dysregulation during diabetic ketoacidosis: Results from the diabetic kidney alarm (DKA) study. J Diabetes Complications. 2022 06; 36(6):108203.
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Postolache TT, Upadhyaya SK, Spector AM, Mohyuddin I, Constantine N, Ernst RK, Wadhawan A, Dutra SVO, Dagdag A, Makkar H, Lowry CA, Akram F, Fuchs D, Brenner LA, Groer MW, Reynolds MA. Decreasing Tryptophan and Increasing Neopterin Plasma Levels During Pregnancy are Associated with High First Trimester Porphyromonas gingivalis K-Serotype IgG Serointensity in a Cohort of Hispanic Women. Curr Top Med Chem. 2022; 22(25):2126-2144.
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D'Alessandro A, Thomas T, Akpan IJ, Reisz JA, Cendali FI, Gamboni F, Nemkov T, Thangaraju K, Katneni U, Tanaka K, Kahn S, Wei AZ, Valk JE, Hudson KE, Roh D, Moriconi C, Zimring JC, Hod EA, Spitalnik SL, Buehler PW, Francis RO. Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19. Cells. 2021 09 02; 10(9).
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Denburg MR, Xu Y, Abraham AG, Coresh J, Chen J, Grams ME, Feldman HI, Kimmel PL, Rebholz CM, Rhee EP, Vasan RS, Warady BA, Furth SL. Metabolite Biomarkers of CKD Progression in Children. Clin J Am Soc Nephrol. 2021 08; 16(8):1178-1189.
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Clement CC, D'Alessandro A, Thangaswamy S, Chalmers S, Furtado R, Spada S, Mondanelli G, Ianni F, Gehrke S, Gargaro M, Manni G, Cara LCL, Runge P, Tsai WL, Karaman S, Arasa J, Fernandez-Rodriguez R, Beck A, Macchiarulo A, Gadina M, Halin C, Fallarino F, Skobe M, Veldhoen M, Moretti S, Formenti S, Demaria S, Soni RK, Galarini R, Sardella R, Lauvau G, Putterman C, Alitalo K, Grohmann U, Santambrogio L. 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine. Nat Commun. 2021 07 21; 12(1):4447.
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Berlinberg AJ, Regner EH, Stahly A, Brar A, Reisz JA, Gerich ME, Fennimore BP, Scott FI, Freeman AE, Kuhn KA. Multi 'Omics Analysis of Intestinal Tissue in Ankylosing Spondylitis Identifies Alterations in the Tryptophan Metabolism Pathway. Front Immunol. 2021; 12:587119.
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Chu SH, Cui J, Sparks JA, Lu B, Tedeschi SK, Speyer CB, Moss L, Feser ML, Kelmenson LB, Mewshaw EA, Edison JD, Deane KD, Clish C, Lasky-Su J, Karlson EW, Costenbader KH. Circulating plasma metabolites and risk of rheumatoid arthritis in the Nurses' Health Study. Rheumatology (Oxford). 2020 11 01; 59(11):3369-3379.
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Liu J, Xue Z, Vann KR, Shi X, Kutateladze TG. Protocol for Biochemical Analysis and Structure Determination of the ZZ Domain of the E3Â Ubiquitin Ligase HERC2. STAR Protoc. 2020 12 18; 1(3):100155.
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Bernstein L, Coughlin CR, Drumm M, Yannicelli S, Rohr F. Inconsistencies in the Nutrition Management of Glutaric Aciduria Type 1: An International Survey. Nutrients. 2020 Oct 16; 12(10).
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