 Biotransformation
"Biotransformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The chemical alteration of an exogenous substance by or in a biological system. The alteration may inactivate the compound or it may result in the production of an active metabolite of an inactive parent compound. The alterations may be divided into METABOLIC DETOXICATION, PHASE I and METABOLIC DETOXICATION, PHASE II.
| Descriptor ID |
D001711
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| MeSH Number(s) |
G03.171 G03.787.225 G07.690.725.225
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Biotransformation".
Below are MeSH descriptors whose meaning is more specific than "Biotransformation".
This graph shows the total number of publications written about "Biotransformation" by people in this website by year, and whether "Biotransformation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1992 | 0 | 3 | 3 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 5 | 5 | | 1995 | 0 | 3 | 3 | | 1996 | 0 | 4 | 4 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 5 | 5 | | 1999 | 0 | 3 | 3 | | 2000 | 0 | 5 | 5 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 4 | 4 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 0 | 2 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 2 | 2 | | 2019 | 2 | 2 | 4 | | 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Biotransformation" by people in Profiles.
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Dalesio NM, Lee CKK, Hendrix CW, Kerns N, Hsu A, Clarke W, Collaco JM, McGrath-Morrow S, Yaster M, Brown RH, Schwartz AR. Effects of Obstructive Sleep Apnea and Obesity on Morphine Pharmacokinetics in Children. Anesth Analg. 2020 09; 131(3):876-884.
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Reisdorph NA, Hendricks AE, Tang M, Doenges KA, Reisdorph RM, Tooker BC, Quinn K, Borengasser SJ, Nkrumah-Elie Y, Frank DN, Campbell WW, Krebs NF. Nutrimetabolomics reveals food-specific compounds in urine of adults consuming a DASH-style diet. Sci Rep. 2020 01 24; 10(1):1157.
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Achermann S, Mansfeldt CB, Müller M, Johnson DR, Fenner K. Relating Metatranscriptomic Profiles to the Micropollutant Biotransformation Potential of Complex Microbial Communities. Environ Sci Technol. 2020 01 07; 54(1):235-244.
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Niyonsaba E, Easton MW, Feng E, Yu Z, Zhang Z, Sheng H, Kong J, Easterling LF, Milton J, Chobanian HR, Deprez NR, Cancilla MT, Kilaz G, Kenttämaa HI. Differentiation of Deprotonated Acyl-, N-, and O-Glucuronide Drug Metabolites by Using Tandem Mass Spectrometry Based on Gas-Phase Ion-Molecule Reactions Followed by Collision-Activated Dissociation. Anal Chem. 2019 09 03; 91(17):11388-11396.
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Rossmassler K, Snow CD, Taggart D, Brown C, De Long SK. Advancing biomarkers for anaerobic o-xylene biodegradation via metagenomic analysis of a methanogenic consortium. Appl Microbiol Biotechnol. 2019 May; 103(10):4177-4192.
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Rossmassler K, Kim S, Broeckling CD, Galloway S, Prenni J, De Long SK. Impact of primary carbon sources on microbiome shaping and biotransformation of pharmaceuticals and personal care products. Biodegradation. 2019 06; 30(2-3):127-145.
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Achermann S, Falås P, Joss A, Mansfeldt CB, Men Y, Vogler B, Fenner K. Trends in Micropollutant Biotransformation along a Solids Retention Time Gradient. Environ Sci Technol. 2018 10 16; 52(20):11601-11611.
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Achermann S, Bianco V, Mansfeldt CB, Vogler B, Kolvenbach BA, Corvini PFX, Fenner K. Biotransformation of Sulfonamide Antibiotics in Activated Sludge: The Formation of Pterin-Conjugates Leads to Sustained Risk. Environ Sci Technol. 2018 06 05; 52(11):6265-6274.
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Kandel SE, Han LW, Mao Q, Lampe JN. Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7. Drug Metab Dispos. 2017 12; 45(12):1266-1275.
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Kim S, Rossmassler K, Broeckling CD, Galloway S, Prenni J, De Long SK. Impact of inoculum sources on biotransformation of pharmaceuticals and personal care products. Water Res. 2017 11 15; 125:227-236.
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