 Dinoprostone
"Dinoprostone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.
| Descriptor ID |
D015232
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| MeSH Number(s) |
D10.251.355.255.550.250.200 D23.469.050.175.725.250.200
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| Concept/Terms |
Dinoprostone- Dinoprostone
- PGE2 alpha
- alpha, PGE2
- Prostaglandin E2alpha
- E2alpha, Prostaglandin
- Prostaglandin E2
- E2, Prostaglandin
- Prostaglandin E2 alpha
- E2 alpha, Prostaglandin
- alpha, Prostaglandin E2
- PGE2
- PGE2alpha
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Below are MeSH descriptors whose meaning is more general than "Dinoprostone".
Below are MeSH descriptors whose meaning is more specific than "Dinoprostone".
This graph shows the total number of publications written about "Dinoprostone" by people in this website by year, and whether "Dinoprostone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 3 | 5 | 8 | | 1990 | 2 | 6 | 8 | | 1991 | 2 | 5 | 7 | | 1992 | 1 | 2 | 3 | | 1993 | 1 | 3 | 4 | | 1994 | 2 | 1 | 3 | | 1995 | 3 | 0 | 3 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 2 | 3 | | 1998 | 0 | 4 | 4 | | 1999 | 2 | 1 | 3 | | 2000 | 2 | 1 | 3 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 4 | 4 | | 2003 | 1 | 1 | 2 | | 2004 | 6 | 6 | 12 | | 2005 | 2 | 3 | 5 | | 2006 | 1 | 4 | 5 | | 2007 | 1 | 3 | 4 | | 2008 | 1 | 2 | 3 | | 2009 | 3 | 4 | 7 | | 2010 | 0 | 3 | 3 | | 2011 | 2 | 5 | 7 | | 2012 | 0 | 1 | 1 | | 2013 | 3 | 2 | 5 | | 2014 | 2 | 4 | 6 | | 2015 | 3 | 2 | 5 | | 2016 | 0 | 4 | 4 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dinoprostone" by people in Profiles.
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Halpern AL, Kohtz PD, Rove JY, Ao L, Meng X, Fullerton DA, Weyant MJ. Inhibition of secretory phospholipase A2 IIa attenuates prostaglandin E2-induced invasiveness in lung adenocarcinoma. Mol Cell Biochem. 2019 Jun; 456(1-2):145-156.
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Turcotte C, Zarini S, Jean S, Martin C, Murphy RC, Marsolais D, Laviolette M, Blanchet MR, Flamand N. The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors. J Immunol. 2017 04 15; 198(8):3255-3263.
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Montford JR, Lehman AM, Scobey MS, Weiser-Evans MC, Nemenoff RA, Furgeson SB. Cytosolic phospholipase A2a increases proliferation and de-differentiation of human renal tubular epithelial cells. Prostaglandins Other Lipid Mediat. 2016 11; 126:1-8.
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Tufa DM, Ahmad F, Chatterjee D, Ahrenstorf G, Schmidt RE, Jacobs R. IL-1ß limits the extent of human 6-sulfo LacNAc dendritic cell (slanDC)-mediated NK cell activation and regulates CD95-induced apoptosis. Cell Mol Immunol. 2017 Dec; 14(12):976-985.
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Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P. COX-2 modulates mammary tumor progression in response to collagen density. Breast Cancer Res. 2016 Mar 22; 18(1):35.
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Yun B, Lee H, Jayaraja S, Suram S, Murphy RC, Leslie CC. Prostaglandins from Cytosolic Phospholipase A2a/Cyclooxygenase-1 Pathway and Mitogen-activated Protein Kinases Regulate Gene Expression in Candida albicans-infected Macrophages. J Biol Chem. 2016 Mar 25; 291(13):7070-86.
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McCarthy MK, Procario MC, Wilke CA, Moore BB, Weinberg JB. Prostaglandin E2 Production and T Cell Function in Mouse Adenovirus Type 1 Infection following Allogeneic Bone Marrow Transplantation. PLoS One. 2015; 10(9):e0139235.
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Trikha A, Kingdom T. Chronic Rhinosinusitis. J Allergy Clin Immunol Pract. 2015 Sep-Oct; 3(5):821-2; quiz 823.
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Marentette JO, Hurst RE, McHowat J. Impaired Expression of Prostaglandin E2 (PGE2) Synthesis and Degradation Enzymes during Differentiation of Immortalized Urothelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome. PLoS One. 2015; 10(6):e0129466.
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Müller C, Tufa DM, Chatterjee D, Mühlradt PF, Schmidt RE, Jacobs R. The TLR-2/TLR-6 agonist macrophage-activating lipopeptide-2 augments human NK cell cytotoxicity when PGE2 production by monocytes is inhibited by a COX-2 blocker. Cancer Immunol Immunother. 2015 Sep; 64(9):1175-84.
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