 Aphasia, Primary Progressive
"Aphasia, Primary Progressive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
| Descriptor ID |
D018888
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| MeSH Number(s) |
C10.228.140.380.132 C10.597.606.150.500.800.100.155 C23.888.592.604.150.500.800.100.155 F03.615.400.125
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| Concept/Terms |
Aphasia, Primary Progressive- Aphasia, Primary Progressive
- Aphasias, Primary Progressive
- Primary Progressive Aphasia
- Primary Progressive Aphasias
- Progressive Aphasia, Primary
- Progressive Aphasias, Primary
- Mesulam's Syndrome
- Syndrome, Mesulam's
- Mesulam Syndrome
- Syndrome, Mesulam
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Below are MeSH descriptors whose meaning is more general than "Aphasia, Primary Progressive".
Below are MeSH descriptors whose meaning is more specific than "Aphasia, Primary Progressive".
This graph shows the total number of publications written about "Aphasia, Primary Progressive" by people in this website by year, and whether "Aphasia, Primary Progressive" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aphasia, Primary Progressive" by people in Profiles.
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Geraudie A, Pressman PS, Pariente J, Millanski C, Palser ER, Ratnasiri BM, Battistella G, Mandelli ML, Miller ZA, Miller BL, Sturm V, Rankin KP, Gorno-Tempini ML, Montembeault M. Expressive Prosody in Patients With Focal Anterior Temporal Neurodegeneration. Neurology. 2023 08 22; 101(8):e825-e835.
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Mesulam MM, Coventry CA, Bigio EH, Sridhar J, Gill N, Fought AJ, Zhang H, Thompson CK, Geula C, Gefen T, Flanagan M, Mao Q, Weintraub S, Rogalski EJ. Neuropathological fingerprints of survival, atrophy and language in primary progressive aphasia. Brain. 2022 06 30; 145(6):2133-2148.
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Ohm DT, Fought AJ, Martersteck A, Coventry C, Sridhar J, Gefen T, Weintraub S, Bigio E, Mesulam MM, Rogalski E, Geula C. Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer's disease. Brain Pathol. 2021 01; 31(1):189-204.
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Ohm DT, Fought AJ, Rademaker A, Kim G, Sridhar J, Coventry C, Gefen T, Weintraub S, Bigio E, Mesulam MM, Rogalski E, Geula C. Neuropathologic basis of in vivo cortical atrophy in the aphasic variant of Alzheimer's disease. Brain Pathol. 2020 03; 30(2):332-344.
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Rogalski EJ, Sridhar J, Martersteck A, Rader B, Cobia D, Arora AK, Fought AJ, Bigio EH, Weintraub S, Mesulam MM, Rademaker A. Clinical and cortical decline in the aphasic variant of Alzheimer's disease. Alzheimers Dement. 2019 04; 15(4):543-552.
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Santos-Santos MA, Rabinovici GD, Iaccarino L, Ayakta N, Tammewar G, Lobach I, Henry ML, Hubbard I, Mandelli ML, Spinelli E, Miller ZA, Pressman PS, O'Neil JP, Ghosh P, Lazaris A, Meyer M, Watson C, Yoon SJ, Rosen HJ, Grinberg L, Seeley WW, Miller BL, Jagust WJ, Gorno-Tempini ML. Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia. JAMA Neurol. 2018 03 01; 75(3):342-352.
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Pressman PS, Simpson M, Gola K, Shdo SM, Spinelli EG, Miller BL, Gorno-Tempini ML, Rankin K, Levenson RW. Observing conversational laughter in frontotemporal dementia. J Neurol Neurosurg Psychiatry. 2017 05; 88(5):418-424.
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Gola KA, Shany-Ur T, Pressman P, Sulman I, Galeana E, Paulsen H, Nguyen L, Wu T, Adhimoolam B, Poorzand P, Miller BL, Rankin KP. A neural network underlying intentional emotional facial expression in neurodegenerative disease. Neuroimage Clin. 2017; 14:672-678.
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Binney RJ, Henry ML, Babiak M, Pressman PS, Santos-Santos MA, Narvid J, Mandelli ML, Strain PJ, Miller BL, Rankin KP, Rosen HJ, Gorno-Tempini ML. Reading words and other people: A comparison of exception word, familiar face and affect processing in the left and right temporal variants of primary progressive aphasia. Cortex. 2016 09; 82:147-163.
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Miller ZA, Mandelli ML, Rankin KP, Henry ML, Babiak MC, Frazier DT, Lobach IV, Bettcher BM, Wu TQ, Rabinovici GD, Graff-Radford NR, Miller BL, Gorno-Tempini ML. Handedness and language learning disability differentially distribute in progressive aphasia variants. Brain. 2013 Nov; 136(Pt 11):3461-73.
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