 Upstream Stimulatory Factors
"Upstream Stimulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitously expressed basic HELIX-LOOP-HELIX MOTIF transcription factors. They bind CANNTG sequences in the promoters of a variety of GENES involved in carbohydrate and lipid metabolism.
| Descriptor ID |
D051720
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| MeSH Number(s) |
D12.776.260.103.937 D12.776.930.125.937
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| Concept/Terms |
Upstream Stimulatory Factors- Upstream Stimulatory Factors
- USF Transcription Factors
- Helix-Loop-Helix Activator USF
- Helix Loop Helix Activator USF
- USF, Helix-Loop-Helix Activator
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Below are MeSH descriptors whose meaning is more general than "Upstream Stimulatory Factors".
Below are MeSH descriptors whose meaning is more specific than "Upstream Stimulatory Factors".
This graph shows the total number of publications written about "Upstream Stimulatory Factors" by people in this website by year, and whether "Upstream Stimulatory Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Upstream Stimulatory Factors" by people in Profiles.
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Ni Y, Seballos S, Fletcher B, Romigh T, Yehia L, Mester J, Senter L, Niazi F, Saji M, Ringel MD, LaFramboise T, Eng C. Germline compound heterozygous poly-glutamine deletion in USF3 may be involved in predisposition to heritable and sporadic epithelial thyroid carcinoma. Hum Mol Genet. 2017 01 15; 26(2):243-257.
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Cruickshank MN, Dods J, Taylor RL, Karimi M, Fenwick EJ, Quail EA, Rea AJ, Holers VM, Abraham LJ, Ulgiati D. Analysis of tandem E-box motifs within human Complement receptor 2 (CR2/CD21) promoter reveals cell specific roles for RP58, E2A, USF and localized chromatin accessibility. Int J Biochem Cell Biol. 2015 Jul; 64:107-19.
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Pawlus MR, Wang L, Murakami A, Dai G, Hu CJ. STAT3 or USF2 contributes to HIF target gene specificity. PLoS One. 2013; 8(8):e72358.
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Befani C, Mylonis I, Gkotinakou IM, Georgoulias P, Hu CJ, Simos G, Liakos P. Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells. Int J Biochem Cell Biol. 2013 Nov; 45(11):2359-68.
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Pawlus MR, Wang L, Ware K, Hu CJ. Upstream stimulatory factor 2 and hypoxia-inducible factor 2a (HIF2a) cooperatively activate HIF2 target genes during hypoxia. Mol Cell Biol. 2012 Nov; 32(22):4595-610.
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Wilson GM, Fielding AB, Simon GC, Yu X, Andrews PD, Hames RS, Frey AM, Peden AA, Gould GW, Prekeris R. The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. Mol Biol Cell. 2005 Feb; 16(2):849-60.
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Jackson SM, Gutierrez-Hartmann A, Hoeffler JP. Upstream stimulatory factor, a basic-helix-loop-helix-zipper protein, regulates the activity of the alpha-glycoprotein hormone subunit gene in pituitary cells. Mol Endocrinol. 1995 Mar; 9(3):278-91.
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