 Antidepressive Agents
"Antidepressive Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
| Descriptor ID |
D000928
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| MeSH Number(s) |
D27.505.954.427.700.122
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| Concept/Terms |
Antidepressive Agents- Antidepressive Agents
- Agents, Antidepressive
- Antidepressant Drugs
- Drugs, Antidepressant
- Antidepressants
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Below are MeSH descriptors whose meaning is more general than "Antidepressive Agents".
Below are MeSH descriptors whose meaning is more specific than "Antidepressive Agents".
This graph shows the total number of publications written about "Antidepressive Agents" by people in this website by year, and whether "Antidepressive Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 1999 | 1 | 2 | 3 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2005 | 4 | 4 | 8 | | 2006 | 2 | 3 | 5 | | 2007 | 5 | 0 | 5 | | 2008 | 3 | 8 | 11 | | 2009 | 6 | 2 | 8 | | 2010 | 5 | 1 | 6 | | 2011 | 8 | 2 | 10 | | 2012 | 9 | 8 | 17 | | 2013 | 6 | 5 | 11 | | 2014 | 10 | 2 | 12 | | 2015 | 7 | 3 | 10 | | 2016 | 11 | 6 | 17 | | 2017 | 9 | 0 | 9 | | 2018 | 8 | 5 | 13 | | 2019 | 6 | 5 | 11 | | 2020 | 5 | 4 | 9 | | 2021 | 3 | 4 | 7 | | 2022 | 1 | 3 | 4 | | 2023 | 1 | 3 | 4 | | 2024 | 4 | 6 | 10 | | 2025 | 4 | 1 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Antidepressive Agents" by people in Profiles.
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Gomez-Lumbreras A, Tawfik AG, Del Fiol G, Kawamoto K, Reese T, Trinkley K, Jones A, Mitchell J, Malone DC. Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta-analysis. Br J Clin Pharmacol. 2026 Mar; 92(3):793-808.
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Ali DA, Hale E, Ascencio A, Berkowitz SJ. Antidepressant pharmacotherapy in childhood PTSD with and without comorbid ADHD: a nationwide retrospective study. J Psychiatr Res. 2025 Oct; 190:199-204.
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Whaites Heinonen E, Johnson DL, Todd A, Chambers CD. Lower Adherence to Breastfeeding Recommendations in Mothers Treated With Antirheumatic and Antidepressant Medications. J Hum Lact. 2025 Aug; 41(3):412-422.
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Ozmen O, Rush E, Park BH, Jones M, Trafton J, Brenner L, Rupper RW, Ward M, Nebeker JR, Pizer SD. Combining Machine Learning and Comparative Effectiveness Methodology to Study Primary Care Pharmacotherapy Pathways for Veterans With Depression. Med Care. 2025 Jun 01; 63(6):422-429.
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Whaites Heinonen E, Bertrand K, Chambers C. Macronutrients in Human Milk Exposed to Antidepressant and Anti-Inflammatory Medications. JAMA Netw Open. 2025 01 02; 8(1):e2453332.
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Fabiano N, Wong S, Gupta A, Tran J, Bhambra N, Min KK, Dragioti E, Barbui C, Fiedorowicz JG, Gosling CJ, Cortese S, Gandhi J, Saraf G, Shorr R, Vigod SN, Frey BN, Delorme R, Solmi M. Safety of psychotropic medications in pregnancy: an umbrella review. Mol Psychiatry. 2025 Jan; 30(1):327-335.
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Petimar J, Young JG, Yu H, Rifas-Shiman SL, Daley MF, Heerman WJ, Janicke DM, Jones WS, Lewis KH, Lin PD, Prentice C, Merriman JW, Toh S, Block JP. Medication-Induced Weight Change Across Common Antidepressant Treatments : A Target Trial Emulation Study. Ann Intern Med. 2024 Aug; 177(8):993-1003.
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Fortney JC, Kaysen DL, Engel CC, Cerimele JM, Nolan JP, Chase E, Blanchard BE, Hauge S, Bechtel J, Moore DL, Taylor A, Acierno R, Nagel N, Sripada RK, Painter JT, DeBeer BB, Bluett E, Teo AR, Morland LA, Heagerty PJ. Sequenced Treatment Effectiveness for Posttraumatic Stress (STEPS) Trial: A protocol for a pragmatic comparative effectiveness trial with baseline results. Contemp Clin Trials. 2024 Sep; 144:107606.
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Page CE, Epperson CN, Novick AM, Duffy KA, Thompson SM. Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder. Mol Psychiatry. 2024 Dec; 29(12):3802-3813.
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Reis DJ, Kinney AR, Forster JE, Stearns-Yoder KA, Kittel JA, Wood AE, Oslin DW, Brenner LA, Simonetti JA. Longitudinal invariance of the Patient Health Questionnaire-9 among patients receiving pharmacotherapy for major depressive disorder: A secondary analysis of clinical trial data. Psychol Assess. 2024 Aug; 36(8):462-471.
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