 Immune Tolerance
"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
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| MeSH Number(s) |
G12.535.425
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1993 | 3 | 5 | 8 | | 1994 | 1 | 6 | 7 | | 1996 | 2 | 2 | 4 | | 1997 | 2 | 4 | 6 | | 1998 | 0 | 2 | 2 | | 1999 | 1 | 3 | 4 | | 2000 | 2 | 4 | 6 | | 2001 | 3 | 2 | 5 | | 2002 | 3 | 1 | 4 | | 2003 | 1 | 2 | 3 | | 2004 | 4 | 5 | 9 | | 2005 | 4 | 4 | 8 | | 2006 | 6 | 4 | 10 | | 2007 | 3 | 2 | 5 | | 2008 | 8 | 1 | 9 | | 2009 | 5 | 3 | 8 | | 2010 | 5 | 5 | 10 | | 2011 | 3 | 4 | 7 | | 2012 | 6 | 5 | 11 | | 2013 | 4 | 1 | 5 | | 2014 | 6 | 5 | 11 | | 2015 | 4 | 3 | 7 | | 2016 | 1 | 7 | 8 | | 2017 | 5 | 6 | 11 | | 2018 | 4 | 6 | 10 | | 2019 | 3 | 5 | 8 | | 2020 | 1 | 1 | 2 | | 2021 | 2 | 6 | 8 | | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Williams MM, Richer JK. Revealing Molecular Mechanisms Supporting Trophoblast-Mediated Maternal Immune Tolerance. Endocrinology. 2022 08 01; 163(8).
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Getahun A. Role of inhibitory signaling in peripheral B cell tolerance. Immunol Rev. 2022 05; 307(1):27-42.
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Neef T, Ifergan I, Beddow S, Penaloza-MacMaster P, Haskins K, Shea LD, Podojil JR, Miller SD. Tolerance Induced by Antigen-Loaded PLG Nanoparticles Affects the Phenotype and Trafficking of Transgenic CD4+ and CD8+ T Cells. Cells. 2021 12 07; 10(12).
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Jacobelli J, Buser AE, Heiden DL, Friedman RS. Autoimmunity in motion: Mechanisms of immune regulation and destruction revealed by in vivo imaging. Immunol Rev. 2022 03; 306(1):181-199.
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Hsieh EW, Hernandez JD. Clean up by aisle 2: roles for IL-2 receptors in host defense and tolerance. Curr Opin Immunol. 2021 10; 72:298-308.
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Tengesdal IW, Dinarello A, Powers NE, Burchill MA, Joosten LAB, Marchetti C, Dinarello CA. Tumor NLRP3-Derived IL-1ß Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression. Front Immunol. 2021; 12:661323.
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Brusko TM, Russ HA, Stabler CL. Strategies for durable ß cell replacement in type 1 diabetes. Science. 2021 07 30; 373(6554):516-522.
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Alves da Costa T, Peterson JN, Lang J, Shulman J, Liang X, Freed BM, Boackle SA, Lauzurica P, Torres RM, Pelanda R. Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice. Proc Natl Acad Sci U S A. 2021 04 20; 118(16).
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Kemp SA, Collier DA, Datir RP, Ferreira IATM, Gayed S, Jahun A, Hosmillo M, Rees-Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N, Sharrocks K, Blane E, Modis Y, Leigh KE, Briggs JAG, van Gils MJ, Smith KGC, Bradley JR, Smith C, Doffinger R, Ceron-Gutierrez L, Barcenas-Morales G, Pollock DD, Goldstein RA, Smielewska A, Skittrall JP, Gouliouris T, Goodfellow IG, Gkrania-Klotsas E, Illingworth CJR, McCoy LE, Gupta RK. SARS-CoV-2 evolution during treatment of chronic infection. Nature. 2021 04; 592(7853):277-282.
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Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. J Exp Med. 2021 02 01; 218(2).
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