 Immune Tolerance
"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
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| MeSH Number(s) |
G12.535.425
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 3 | 1 | 4 | | 1992 | 1 | 0 | 1 | | 1993 | 2 | 5 | 7 | | 1994 | 2 | 7 | 9 | | 1995 | 0 | 1 | 1 | | 1996 | 2 | 2 | 4 | | 1997 | 2 | 4 | 6 | | 1998 | 1 | 4 | 5 | | 1999 | 1 | 3 | 4 | | 2000 | 2 | 4 | 6 | | 2001 | 3 | 2 | 5 | | 2002 | 3 | 1 | 4 | | 2003 | 1 | 2 | 3 | | 2004 | 4 | 5 | 9 | | 2005 | 5 | 4 | 9 | | 2006 | 5 | 5 | 10 | | 2007 | 4 | 3 | 7 | | 2008 | 8 | 1 | 9 | | 2009 | 4 | 3 | 7 | | 2010 | 4 | 6 | 10 | | 2011 | 3 | 4 | 7 | | 2012 | 6 | 4 | 10 | | 2013 | 4 | 1 | 5 | | 2014 | 7 | 4 | 11 | | 2015 | 4 | 4 | 8 | | 2016 | 1 | 7 | 8 | | 2017 | 4 | 7 | 11 | | 2018 | 3 | 7 | 10 | | 2019 | 3 | 6 | 9 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Brusko TM, Russ HA, Stabler CL. Strategies for durable ß cell replacement in type 1 diabetes. Science. 2021 07 30; 373(6554):516-522.
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Kemp SA, Collier DA, Datir RP, Ferreira IATM, Gayed S, Jahun A, Hosmillo M, Rees-Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N, Sharrocks K, Blane E, Modis Y, Leigh KE, Briggs JAG, van Gils MJ, Smith KGC, Bradley JR, Smith C, Doffinger R, Ceron-Gutierrez L, Barcenas-Morales G, Pollock DD, Goldstein RA, Smielewska A, Skittrall JP, Gouliouris T, Goodfellow IG, Gkrania-Klotsas E, Illingworth CJR, McCoy LE, Gupta RK. SARS-CoV-2 evolution during treatment of chronic infection. Nature. 2021 04; 592(7853):277-282.
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Reed B, Crawford F, Hill RC, Jin N, White J, Krovi SH, Marrack P, Hansen K, Kappler JW. Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation. J Exp Med. 2021 02 01; 218(2).
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Gray JI, Al-Khabouri S, Morton F, Clambey ET, Gapin L, Matsuda JL, Kappler JW, Marrack P, Garside P, Otto TD, MacLeod MKL. Tolerance induction in memory CD4 T cells is partial and reversible. Immunology. 2021 01; 162(1):68-83.
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Chriswell ME, Kuhn KA. Microbiota-mediated mucosal inflammation in arthritis. Best Pract Res Clin Rheumatol. 2019 12; 33(6):101492.
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Mina MJ, Kula T, Leng Y, Li M, de Vries RD, Knip M, Siljander H, Rewers M, Choy DF, Wilson MS, Larman HB, Nelson AN, Griffin DE, de Swart RL, Elledge SJ. Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens. Science. 2019 11 01; 366(6465):599-606.
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Onyema OO, Guo Y, Mahgoub B, Wang Q, Manafi A, Mei Z, Banerjee A, Li D, Stoler MH, Zaidi MT, Schrum AG, Kreisel D, Gelman AE, Jacobsen EA, Krupnick AS. Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction. JCI Insight. 2019 06 06; 4(11).
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Shaker M, Greenhawt M. Providing cost-effective care for food allergy. Ann Allergy Asthma Immunol. 2019 09; 123(3):240-248.e1.
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Jamison BL, Neef T, Goodspeed A, Bradley B, Baker RL, Miller SD, Haskins K. Nanoparticles Containing an Insulin-ChgA Hybrid Peptide Protect from Transfer of Autoimmune Diabetes by Shifting the Balance between Effector T Cells and Regulatory T Cells. J Immunol. 2019 07 01; 203(1):48-57.
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Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34).
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