 Transcriptional Activation
"Transcriptional Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Processes that stimulate the GENETIC TRANSCRIPTION of a gene or set of genes.
| Descriptor ID |
D015533
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| MeSH Number(s) |
G05.308.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcriptional Activation".
Below are MeSH descriptors whose meaning is more specific than "Transcriptional Activation".
This graph shows the total number of publications written about "Transcriptional Activation" by people in this website by year, and whether "Transcriptional Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 3 | 4 | | 1996 | 1 | 2 | 3 | | 1997 | 3 | 6 | 9 | | 1998 | 3 | 1 | 4 | | 1999 | 2 | 4 | 6 | | 2000 | 0 | 6 | 6 | | 2001 | 2 | 4 | 6 | | 2002 | 4 | 5 | 9 | | 2003 | 4 | 9 | 13 | | 2004 | 4 | 9 | 13 | | 2005 | 3 | 9 | 12 | | 2006 | 4 | 11 | 15 | | 2007 | 2 | 5 | 7 | | 2008 | 3 | 11 | 14 | | 2009 | 3 | 12 | 15 | | 2010 | 3 | 8 | 11 | | 2011 | 2 | 5 | 7 | | 2012 | 3 | 6 | 9 | | 2013 | 5 | 14 | 19 | | 2014 | 3 | 3 | 6 | | 2015 | 2 | 4 | 6 | | 2016 | 2 | 6 | 8 | | 2017 | 3 | 7 | 10 | | 2018 | 8 | 5 | 13 | | 2019 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 4 | 4 | | 2022 | 2 | 1 | 3 | | 2023 | 0 | 4 | 4 | | 2024 | 2 | 3 | 5 | | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Transcriptional Activation" by people in Profiles.
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Nagel M, Taatjes DJ. Regulation of RNA polymerase II transcription through re-initiation and bursting. Mol Cell. 2025 May 15; 85(10):1907-1919.
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Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L, Booth GT, Geng F, Liu Y, Gomez-Salinero JM, Shieh JH, Redmond D, Xiang JZ, Josefowicz SZ, Trapnell C, Pietras EM, Spencer JA, Levine R, Xiao W, Zangi L, Hadland B, Dick JE, Xie SZ, Rafii S. Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing. Nat Immunol. 2025 Mar; 26(3):378-390.
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Zhao L, Nakajima R, Zhou Y, Shirasawa M, Fikriyanti M, Kamiya Y, Toh H, Komori H, Iwanaga R, Bradford AP, Nishitani H, Kurayoshi K, Araki K, Ohtani K. The N-Terminal Region of the Transcription Factor E2F1 Contains a Novel Transactivation Domain and Recruits General Transcription Factor GTF2H2. Biomolecules. 2024 Oct 25; 14(11).
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Shirasawa M, Nakajima R, Zhou Y, Zhao L, Fikriyanti M, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani K. Activation of the CDK7 Gene, Coding for the Catalytic Subunit of the Cyclin-Dependent Kinase (CDK)-Activating Kinase (CAK) and General Transcription Factor II H, by the Trans-Activator Protein Tax of Human T-Cell Leukemia Virus Type-1. Genes (Basel). 2024 Aug 15; 15(8).
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Hyder U, Challa A, Thornton M, Nandu T, Kraus WL, D'Orso I. KAP1 negatively regulates RNA polymerase II elongation kinetics to activate signal-induced transcription. Nat Commun. 2024 Jul 12; 15(1):5859.
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Hayati RF, Nakajima R, Zhou Y, Shirasawa M, Zhao L, Fikriyanti M, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani K. Trans-Activation of the Coactivator-Associated Arginine Methyltransferase 1 (Carm1) Gene by the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1. Genes (Basel). 2024 May 27; 15(6).
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Randolph K, Hyder U, Challa A, Perez E, D'Orso I. Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation. Viruses. 2024 01 13; 16(1).
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Lammer NC, Ashraf HM, Ugay DA, Spencer SL, Allen MA, Batey RT, Wuttke DS. RNA binding by the glucocorticoid receptor attenuates dexamethasone-induced gene activation. Sci Rep. 2023 06 09; 13(1):9385.
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Battistello E, Hixon KA, Comstock DE, Collings CK, Chen X, Rodriguez Hernaez J, Lee S, Cervantes KS, Hinkley MM, Ntatsoulis K, Cesarano A, Hockemeyer K, Haining WN, Witkowski MT, Qi J, Tsirigos A, Perna F, Aifantis I, Kadoch C. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion. Mol Cell. 2023 04 20; 83(8):1216-1236.e12.
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Liu Y, Ma L, Li M, Tian Z, Yang M, Wu X, Wang X, Shang G, Xie M, Chen Y, Liu X, Jiang L, Wu W, Xu C, Xia L, Li G, Dai S, Chen Z. Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res. 2023 02 22; 51(3):1443-1457.
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