 Amyloid beta-Peptides
"Amyloid beta-Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.
| Descriptor ID |
D016229
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| MeSH Number(s) |
D12.644.024 D12.776.049.407.249.500 D12.776.543.039.500
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| Concept/Terms |
Amyloid beta-Peptides- Amyloid beta-Peptides
- Amyloid beta Peptides
- beta-Peptides, Amyloid
- Alzheimer's ABP
- ABP, Alzheimer's
- Alzheimer ABP
- Alzheimers ABP
- Alzheimer's Amyloid Fibril Protein
- Amyloid AD-AP
- AD-AP, Amyloid
- Amyloid AD AP
- beta-Amyloid Protein
- Protein, beta-Amyloid
- beta Amyloid Protein
- Amyloid beta-Protein
- Amyloid beta Protein
- beta-Protein, Amyloid
- Amyloid beta-Proteins
- Amyloid beta Proteins
- beta-Proteins, Amyloid
- Amyloid Fibril Protein, Alzheimer's
- Amyloid Protein A4
- Protein A4, Amyloid
- Alzheimer beta-Protein
- Alzheimer beta Protein
- beta-Protein, Alzheimer
- Amyloid beta-Peptide
- Amyloid beta Peptide
- beta-Peptide, Amyloid
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Below are MeSH descriptors whose meaning is more general than "Amyloid beta-Peptides".
Below are MeSH descriptors whose meaning is more specific than "Amyloid beta-Peptides".
This graph shows the total number of publications written about "Amyloid beta-Peptides" by people in this website by year, and whether "Amyloid beta-Peptides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1997 | 1 | 0 | 1 | | 1998 | 2 | 1 | 3 | | 1999 | 2 | 0 | 2 | | 2000 | 3 | 2 | 5 | | 2001 | 1 | 1 | 2 | | 2002 | 3 | 0 | 3 | | 2003 | 5 | 2 | 7 | | 2004 | 4 | 0 | 4 | | 2005 | 4 | 1 | 5 | | 2006 | 4 | 1 | 5 | | 2007 | 3 | 1 | 4 | | 2008 | 4 | 1 | 5 | | 2009 | 5 | 3 | 8 | | 2010 | 4 | 1 | 5 | | 2011 | 4 | 1 | 5 | | 2012 | 6 | 3 | 9 | | 2013 | 2 | 2 | 4 | | 2014 | 3 | 1 | 4 | | 2015 | 2 | 4 | 6 | | 2016 | 5 | 3 | 8 | | 2017 | 2 | 2 | 4 | | 2018 | 6 | 1 | 7 | | 2019 | 8 | 3 | 11 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amyloid beta-Peptides" by people in Profiles.
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Vugmeyster L, Ostrovsky D, Fu R. Deuteron Quadrupolar Chemical Exchange Saturation Transfer (Q-CEST) Solid-State NMR for Static Powder Samples: Approach and Applications to Amyloid-ß Fibrils. Chemphyschem. 2020 02 04; 21(3):220-231.
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Vander Zanden CM, Wampler L, Bowers I, Watkins EB, Majewski J, Chi EY. Fibrillar and Nonfibrillar Amyloid Beta Structures Drive Two Modes of Membrane-Mediated Toxicity. Langmuir. 2019 12 03; 35(48):16024-16036.
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Vugmeyster L, Au DF, Ostrovsky D, Kierl B, Fu R, Hu ZW, Qiang W. Effect of Post-Translational Modifications and Mutations on Amyloid-ß Fibrils Dynamics at N Terminus. Biophys J. 2019 10 15; 117(8):1524-1535.
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Vugmeyster L, Au DF, Ostrovsky D, Fu R. Deuteron Solid-State NMR Relaxation Measurements Reveal Two Distinct Conformational Exchange Processes in the Disordered N-Terminal Domain of Amyloid-ß Fibrils. Chemphyschem. 2019 07 02; 20(13):1680-1689.
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Hu ZW, Vugmeyster L, Au DF, Ostrovsky D, Sun Y, Qiang W. Molecular structure of an N-terminal phosphorylated ß-amyloid fibril. Proc Natl Acad Sci U S A. 2019 06 04; 116(23):11253-11258.
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Shea D, Hsu CC, Bi TM, Paranjapye N, Childers MC, Cochran J, Tomberlin CP, Wang L, Paris D, Zonderman J, Varani G, Link CD, Mullan M, Daggett V. a-Sheet secondary structure in amyloid ß-peptide drives aggregation and toxicity in Alzheimer's disease. Proc Natl Acad Sci U S A. 2019 04 30; 116(18):8895-8900.
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Cook SG, Goodell DJ, Restrepo S, Arnold DB, Bayer KU. Simultaneous Live Imaging of Multiple Endogenous Proteins Reveals a Mechanism for Alzheimer's-Related Plasticity Impairment. Cell Rep. 2019 04 16; 27(3):658-665.e4.
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Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430.
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Guerrero-Gómez D, Mora-Lorca JA, Sáenz-Narciso B, Naranjo-Galindo FJ, Muñoz-Lobato F, Parrado-Fernández C, Goikolea J, Cedazo-Minguez Á, Link CD, Neri C, Sequedo MD, Vázquez-Manrique RP, Fernández-Suárez E, Goder V, Pané R, Cabiscol E, Askjaer P, Cabello J, Miranda-Vizuete A. Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation. Cell Death Differ. 2019 09; 26(9):1545-1565.
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Rogalski EJ, Sridhar J, Martersteck A, Rader B, Cobia D, Arora AK, Fought AJ, Bigio EH, Weintraub S, Mesulam MM, Rademaker A. Clinical and cortical decline in the aphasic variant of Alzheimer's disease. Alzheimers Dement. 2019 04; 15(4):543-552.
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