 Killer Cells, Natural
"Killer Cells, Natural" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
| Descriptor ID |
D007694
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| MeSH Number(s) |
A11.118.637.555.567.537 A15.145.229.637.555.567.537 A15.382.490.555.567.537
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| Concept/Terms |
Killer Cells, Natural- Killer Cells, Natural
- NK Cells
- Cell, NK
- Cells, NK
- NK Cell
- Natural Killer Cells
- Cell, Natural Killer
- Cells, Natural Killer
- Killer Cell, Natural
- Natural Killer Cell
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Below are MeSH descriptors whose meaning is more general than "Killer Cells, Natural".
Below are MeSH descriptors whose meaning is more specific than "Killer Cells, Natural".
This graph shows the total number of publications written about "Killer Cells, Natural" by people in this website by year, and whether "Killer Cells, Natural" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1991 | 1 | 0 | 1 | | 1992 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 1 | 2 | | 1996 | 4 | 1 | 5 | | 1997 | 0 | 3 | 3 | | 1998 | 1 | 4 | 5 | | 1999 | 1 | 3 | 4 | | 2000 | 8 | 5 | 13 | | 2001 | 10 | 2 | 12 | | 2002 | 6 | 6 | 12 | | 2003 | 7 | 5 | 12 | | 2004 | 6 | 6 | 12 | | 2005 | 8 | 7 | 15 | | 2006 | 2 | 4 | 6 | | 2007 | 10 | 5 | 15 | | 2008 | 7 | 11 | 18 | | 2009 | 6 | 7 | 13 | | 2010 | 11 | 1 | 12 | | 2011 | 8 | 4 | 12 | | 2012 | 8 | 2 | 10 | | 2013 | 10 | 3 | 13 | | 2014 | 14 | 6 | 20 | | 2015 | 10 | 6 | 16 | | 2016 | 6 | 11 | 17 | | 2017 | 6 | 5 | 11 | | 2018 | 6 | 6 | 12 | | 2019 | 7 | 6 | 13 | | 2020 | 2 | 5 | 7 |
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Below are the most recent publications written about "Killer Cells, Natural" by people in Profiles.
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Gruber CN, Patel RS, Trachtman R, Lepow L, Amanat F, Krammer F, Wilson KM, Onel K, Geanon D, Tuballes K, Patel M, Mouskas K, O'Donnell T, Merritt E, Simons NW, Barcessat V, Del Valle DM, Udondem S, Kang G, Gangadharan S, Ofori-Amanfo G, Laserson U, Rahman A, Kim-Schulze S, Charney AW, Gnjatic S, Gelb BD, Merad M, Bogunovic D. Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C). Cell. 2020 11 12; 183(4):982-995.e14.
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Qian Q, Chowdhury BP, Sun Z, Lenberg J, Alam R, Vivier E, Gorska MM. Maternal diesel particle exposure promotes offspring asthma through NK cell-derived granzyme B. J Clin Invest. 2020 08 03; 130(8):4133-4151.
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Anderson KM, Augusto DG, Dandekar R, Shams H, Zhao C, Yusufali T, Montero-Martín G, Marin WM, Nemat-Gorgani N, Creary LE, Caillier S, Mofrad MRK, Parham P, Fernández-Viña M, Oksenberg JR, Norman PJ, Hollenbach JA. Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease. J Immunol. 2020 09 01; 205(5):1323-1330.
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Clark SE, Schmidt RL, Aguilera ER, Lenz LL. IL-10-producing NK cells exacerbate sublethal Streptococcus pneumoniae infection in the lung. Transl Res. 2020 12; 226:70-82.
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Tufa DM, Shank T, Yingst AM, Trahan GD, Shim S, Lake J, Woods R, Jones K, Verneris MR. Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage. Sci Rep. 2020 04 14; 10(1):6335.
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Klarquist J, Cantrell R, Lehn MA, Lampe K, Hennies CM, Hoebe K, Janssen EM. Type I IFN Drives Experimental Systemic Lupus Erythematosus by Distinct Mechanisms in CD4 T Cells and B Cells. Immunohorizons. 2020 03 11; 4(3):140-152.
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Haverkos BM, Porcu P. Improved outcomes for extranodal natural killer T-cell lymphoma. Lancet Haematol. 2020 04; 7(4):e272-e273.
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Hong JP, McCarthy MK, Davenport BJ, Morrison TE, Diamond MS. Clearance of Chikungunya Virus Infection in Lymphoid Tissues Is Promoted by Treatment with an Agonistic Anti-CD137 Antibody. J Virol. 2019 12 15; 93(24).
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Gyurova IE, Schlums H, Sucharew H, Ambroggio L, Ochayon DE, Win HT, Bryceson YT, Bernstein DI, Waggoner SN. Dynamic Changes in Natural Killer Cell Subset Frequencies in the Absence of Cytomegalovirus Infection. Front Immunol. 2019; 10:2728.
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Pugh J, Nemat-Gorgani N, Djaoud Z, Guethlein LA, Norman PJ, Parham P. In vitro education of human natural killer cells by KIR3DL1. Life Sci Alliance. 2019 12; 2(6).
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