 Primary Graft Dysfunction
"Primary Graft Dysfunction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
| Descriptor ID |
D055031
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| MeSH Number(s) |
C14.907.725.675 C23.550.767.877.750
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Primary Graft Dysfunction".
Below are MeSH descriptors whose meaning is more specific than "Primary Graft Dysfunction".
This graph shows the total number of publications written about "Primary Graft Dysfunction" by people in this website by year, and whether "Primary Graft Dysfunction" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 0 | 1 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 | | 2020 | 2 | 0 | 2 | | 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Primary Graft Dysfunction" by people in Profiles.
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Suarez-Pierre A, Iguidbashian J, Kirsch MJ, Cain MT, Aftab M, Reece TB, Fullerton DA, Rove JY, Cleveland JC, Hoffman JRH. Association of cardiac preservation solution with short-term outcomes after heart transplantation. J Cardiovasc Med (Hagerstown). 2024 02 01; 25(2):158-164.
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Moore HB, Saben J, Rodriguez I, Bababekov YJ, Pomposelli JJ, Yoeli D, Ferrell T, Adams MA, Pshak TJ, Kaplan B, Pomfret EA, Nydam TL. Postoperative fibrinolytic resistance is associated with early allograft dysfunction in liver transplantation: A prospective observational study. Liver Transpl. 2023 07 01; 29(7):724-734.
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King PM, Raymer DS, Shuster J, Crain M, Bhatia A, Hartupee J, Schilling JD. Right Heart Failure While on Left Ventricular Assist Device Support Is Associated with Primary Graft Dysfunction. ASAIO J. 2020 Nov/Dec; 66(10):1137-1141.
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Kemme S, Sundaram SS, Curtis DJ, Lobritto S, Mohammad S, Feldman AG. A community divided: Post-transplant live vaccine practices among Society of Pediatric Liver Transplantation (SPLIT) centers. Pediatr Transplant. 2020 11; 24(7):e13804.
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Leiva-Ju?rez MM, Urso A, Arango Tom?s E, Lederer DJ, Sanchez P, Griffith B, Davis RD, Daneshmand M, Hartwig M, Cantu E, Weyant MJ, Bermudez C, D'Cunha J, Machuca T, Wozniak T, Lynch W, Nemeh H, Mulligan M, Song T, Jessen M, Camp PC, Caldeira C, Whitson B, Kreisel D, Ramzy D, D'Ovidio F. Extended post-ex vivo lung perfusion cold preservation predicts primary graft dysfunction and mortality: Results from a multicentric study. J Heart Lung Transplant. 2020 09; 39(9):954-961.
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Wilkey BJ, Abrams BA. Mitigation of Primary Graft Dysfunction in Lung Transplantation: Current Understanding and Hopes for the Future. Semin Cardiothorac Vasc Anesth. 2020 Mar; 24(1):54-66.
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Smirnova NF, Eickelberg O. Three Is Better than One: An Improved Multiple-Hit Model of Primary Graft Dysfunction. Am J Respir Cell Mol Biol. 2019 Aug; 61(2):141-142.
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Rehm SRT, Smirnova NF, Morrone C, G?tzfried J, Feuchtinger A, Pedersen J, Korkmaz B, Yildirim A?, Jenne DE. Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation. Sci Rep. 2019 07 09; 9(1):9925.
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Stone ML, Everitt MD. Primary graft dysfunction: Worry less about organ quality and do more to improve candidate condition. J Heart Lung Transplant. 2019 06; 38(6):609-610.
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Mowers KL, Simpson KE, Gazit AZ, Eghtesady P, Canter CE, Castleberry CD. Moderate-severe primary graft dysfunction after pediatric heart transplantation. Pediatr Transplant. 2019 03; 23(2):e13340.
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