 Leukemia, Lymphocytic, Chronic, B-Cell
"Leukemia, Lymphocytic, Chronic, B-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
| Descriptor ID |
D015451
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| MeSH Number(s) |
C04.557.337.428.080.125 C15.604.515.560.080.125 C20.683.515.528.080.125
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| Concept/Terms |
Leukemia, Lymphocytic, Chronic, B-Cell- Leukemia, Lymphocytic, Chronic, B-Cell
- Leukemia, Lymphocytic, Chronic, B Cell
- Lymphoma, Lymphocytic, Well-Differentiated
- Lymphoma, Lymphoplasmacytoid, CLL
- Lymphoma, Small Lymphocytic
- Lymphocytic Lymphoma, Small
- Lymphocytic Lymphomas, Small
- Lymphomas, Small Lymphocytic
- Small Lymphocytic Lymphoma
- Small Lymphocytic Lymphomas
- Lymphoma, Small Lymphocytic, Plasmacytoid
- Lymphoma, Small-Cell
- Lymphoma, Small Cell
- Lymphomas, Small-Cell
- Small-Cell Lymphomas
- Lymphoplasmacytoid Lymphoma, CLL
- CLL Lymphoplasmacytoid Lymphoma
- CLL Lymphoplasmacytoid Lymphomas
- Lymphoma, CLL Lymphoplasmacytoid
- Lymphomas, CLL Lymphoplasmacytoid
- Lymphoplasmacytoid Lymphomas, CLL
- Small-Cell Lymphoma
- Small Cell Lymphoma
- Lymphoblastic Leukemia, Chronic
- Chronic Lymphoblastic Leukemia
- Chronic Lymphoblastic Leukemias
- Leukemias, Chronic Lymphoblastic
- Lymphoblastic Leukemias, Chronic
- Lymphocytic Leukemia, Chronic
- Lymphocytic Leukemia, Chronic, B Cell
- Lymphocytic Leukemia, Chronic, B-Cell
- Lymphocytic Lymphoma
- Lymphocytic Lymphomas
- Lymphomas, Lymphocytic
- Lymphocytic Lymphoma, Diffuse, Well Differentiated
- Lymphocytic Lymphoma, Diffuse, Well-Differentiated
- Lymphocytic Lymphoma, Well Differentiated
- Lymphocytic Lymphoma, Well-Differentiated
- Lymphocytic Lymphomas, Well-Differentiated
- Lymphoma, Well-Differentiated Lymphocytic
- Lymphomas, Well-Differentiated Lymphocytic
- Well-Differentiated Lymphocytic Lymphoma
- Well-Differentiated Lymphocytic Lymphomas
- Lymphoma, Lymphocytic
- Lymphoma, Lymphocytic, Diffuse, Well Differentiated
- B-Cell Chronic Lymphocytic Leukemia
- B Cell Chronic Lymphocytic Leukemia
- B-Cell Leukemia, Chronic
- B Cell Leukemia, Chronic
- B-Cell Leukemias, Chronic
- Chronic B-Cell Leukemia
- Chronic B-Cell Leukemias
- Leukemia, Chronic B-Cell
- Leukemias, Chronic B-Cell
- B-Cell Malignancy, Low-Grade
- B-Lymphocytic Leukemia, Chronic
- B Lymphocytic Leukemia, Chronic
- B-Lymphocytic Leukemias, Chronic
- Chronic B-Lymphocytic Leukemia
- Chronic B-Lymphocytic Leukemias
- Leukemia, Chronic B-Lymphocytic
- Leukemias, Chronic B-Lymphocytic
- Chronic Lymphocytic Leukemia
- Chronic Lymphocytic Leukemias
- Lymphocytic Leukemias, Chronic
- Diffuse Well-Differentiated Lymphocytic Lymphoma
- Diffuse Well Differentiated Lymphocytic Lymphoma
- Disrupted In B-Cell Malignancy
- Leukemia, B Cell, Chronic
- Leukemia, B-Cell, Chronic
- Leukemia, Chronic Lymphatic
- Leukemia, Chronic Lymphocytic
- Leukemia, Chronic Lymphocytic, B-Cell
- Leukemia, Lymphoblastic, Chronic
- Leukemia, Lymphocytic, Chronic
- Lymphoma, Lymphocytic, Diffuse, Well-Differentiated
- Lymphoma, Lymphocytic, Well Differentiated
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Lymphocytic, Chronic, B-Cell".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Leukemia [C04.557.337]
- Leukemia, Lymphoid [C04.557.337.428]
- Leukemia, B-Cell [C04.557.337.428.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C04.557.337.428.080.125]
- Hemic and Lymphatic Diseases [C15]
- Lymphatic Diseases [C15.604]
- Lymphoproliferative Disorders [C15.604.515]
- Leukemia, Lymphoid [C15.604.515.560]
- Leukemia, B-Cell [C15.604.515.560.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C15.604.515.560.080.125]
- Immune System Diseases [C20]
- Immunoproliferative Disorders [C20.683]
- Lymphoproliferative Disorders [C20.683.515]
- Leukemia, Lymphoid [C20.683.515.528]
- Leukemia, B-Cell [C20.683.515.528.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C20.683.515.528.080.125]
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Lymphocytic, Chronic, B-Cell".
This graph shows the total number of publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in this website by year, and whether "Leukemia, Lymphocytic, Chronic, B-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2017 | 3 | 0 | 3 | | 2019 | 7 | 0 | 7 | | 2020 | 3 | 0 | 3 | | 2021 | 3 | 0 | 3 | | 2022 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in Profiles.
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Li A, Ambruso SL, Oto OA, Barry M, Edelstein CL. A case report of pre-eclampsia-like endothelial injury in the kidney of an 85-year-old man treated with ibrutinib. BMC Nephrol. 2022 07 23; 23(1):264.
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Smith AL, Eiken AP, Skupa SA, Moore DY, Umeta LT, Smith LM, Lyden ER, D'Angelo CR, Kallam A, Vose JM, Kutateladze TG, El-Gamal D. A Novel Triple-Action Inhibitor Targeting B-Cell Receptor Signaling and BRD4 Demonstrates Preclinical Activity in Chronic Lymphocytic Leukemia. Int J Mol Sci. 2022 Jun 16; 23(12).
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Wierda WG, Brown J, Abramson JS, Awan F, Bilgrami SF, Bociek G, Brander D, Chanan-Khan AA, Coutre SE, Davis RS, Eradat H, Fletcher CD, Gaballa S, Ghobadi A, Hamid MS, Hernandez-Ilizaliturri F, Hill B, Kaesberg P, Kamdar M, Kaplan LD, Khan N, Kipps TJ, Ma S, Mato A, Mosse C, Schuster S, Siddiqi T, Stephens DM, Ujjani C, Wagner-Johnston N, Woyach JA, Ye JC, Dwyer MA, Sundar H. NCCN Guidelines® Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 3.2022. J Natl Compr Canc Netw. 2022 06; 20(6):622-634.
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Wang E, Mi X, Thompson MC, Montoya S, Notti RQ, Afaghani J, Durham BH, Penson A, Witkowski MT, Lu SX, Bourcier J, Hogg SJ, Erickson C, Cui D, Cho H, Singer M, Totiger TM, Chaudhry S, Geyer M, Alencar A, Linley AJ, Palomba ML, Coombs CC, Park JH, Zelenetz A, Roeker L, Rosendahl M, Tsai DE, Ebata K, Brandhuber B, Hyman DM, Aifantis I, Mato A, Taylor J, Abdel-Wahab O. Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors. N Engl J Med. 2022 02 24; 386(8):735-743.
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Cull G, Burger JA, Opat S, Gottlieb D, Verner E, Trotman J, Marlton P, Munoz J, Johnston P, Simpson D, Stern JC, Prathikanti R, Wu K, Novotny W, Huang J, Tam CS. Zanubrutinib for treatment-naïve and relapsed/refractory chronic lymphocytic leukaemia: long-term follow-up of the phase I/II AU-003 study. Br J Haematol. 2022 03; 196(5):1209-1218.
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Muchtar E, Koehler AB, Johnson MJ, Rabe KG, Ding W, Call TG, Leis JF, Kenderian SS, Hayman SR, Wang Y, Hampel PJ, Holets MA, Darby HC, Slager SL, Kay NE, Miao C, Canniff J, Whitaker JA, Levin MJ, Schmid DS, Kennedy RB, Weinberg A, Parikh SA. Humoral and cellular immune responses to recombinant herpes zoster vaccine in patients with chronic lymphocytic leukemia and monoclonal B cell lymphocytosis. Am J Hematol. 2022 01 01; 97(1):90-98.
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Roeker LE, Eyre TA, Thompson MC, Lamanna N, Coltoff AR, Davids MS, Baker PO, Leslie L, Rogers KA, Allan JN, Cordoba R, Lopez-Garcia A, Antic D, Pagel JM, Martinez-Calle N, García-Marco JA, Hernández-Rivas JÁ, Miras F, Coombs CC, Österborg A, Hansson L, Seddon AN, López Jiménez J, Wilson MR, El-Sharkawi D, Wojenski D, Ma S, Munir T, Valenciano S, Seymour E, Barr PM, Pu J, Patten PEM, Perini GF, Huntington SF, Parry H, Sundaram S, Skarbnik A, Kamdar M, Jacobs R, Walter H, Walewska R, Broom A, Lebowitz S, Isaac KM, Portell CA, Ahn IE, Ujjani CS, Shadman M, Skånland SS, Chong EA, Mato AR. COVID-19 in patients with CLL: improved survival outcomes and update on management strategies. Blood. 2021 11 04; 138(18):1768-1773.
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Mato AR, Roeker LE, Lamanna N, Allan JN, Leslie L, Pagel JM, Patel K, Osterborg A, Wojenski D, Kamdar M, Huntington SF, Davids MS, Brown JR, Antic D, Jacobs R, Ahn IE, Pu J, Isaac KM, Barr PM, Ujjani CS, Geyer MB, Berman E, Zelenetz AD, Malakhov N, Furman RR, Koropsak M, Bailey N, Hanson L, Perini GF, Ma S, Ryan CE, Wiestner A, Portell CA, Shadman M, Chong EA, Brander DM, Sundaram S, Seddon AN, Seymour E, Patel M, Martinez-Calle N, Munir T, Walewska R, Broom A, Walter H, El-Sharkawi D, Parry H, Wilson MR, Patten PEM, Hernández-Rivas JÁ, Miras F, Fernández Escalada N, Ghione P, Nabhan C, Lebowitz S, Bhavsar E, López-Jiménez J, Naya D, Garcia-Marco JA, Skånland SS, Cordoba R, Eyre TA. Outcomes of COVID-19 in patients with CLL: a multicenter international experience. Blood. 2020 09 03; 136(10):1134-1143.
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Roeker LE, Dreger P, Brown JR, Lahoud OB, Eyre TA, Brander DM, Skarbnik A, Coombs CC, Kim HT, Davids M, Manchini ST, George G, Shah N, Voorhees TJ, Orchard KH, Walter HS, Arumainathan AK, Sitlinger A, Park JH, Geyer MB, Zelenetz AD, Sauter CS, Giralt SA, Perales MA, Mato AR. Allogeneic stem cell transplantation for chronic lymphocytic leukemia in the era of novel agents. Blood Adv. 2020 08 25; 4(16):3977-3989.
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Wierda WG, Byrd JC, Abramson JS, Bilgrami SF, Bociek G, Brander D, Brown J, Chanan-Khan AA, Chavez JC, Coutre SE, Davis RS, Fletcher CD, Hill B, Kahl BS, Kamdar M, Kaplan LD, Khan N, Kipps TJ, Lim MS, Ma S, Malek S, Mato A, Mosse C, Shadman M, Siddiqi T, Stephens D, Sundaram S, Wagner N, Dwyer M, Sundar H. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2020 02; 18(2):185-217.
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