 Leukemia, Lymphocytic, Chronic, B-Cell
"Leukemia, Lymphocytic, Chronic, B-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
| Descriptor ID |
D015451
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| MeSH Number(s) |
C04.557.337.428.080.125 C15.604.515.560.080.125 C20.683.515.528.080.125
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| Concept/Terms |
Leukemia, Lymphocytic, Chronic, B-Cell- Leukemia, Lymphocytic, Chronic, B-Cell
- Leukemia, Lymphocytic, Chronic, B Cell
- Lymphoma, Lymphocytic, Well-Differentiated
- Lymphoma, Lymphoplasmacytoid, CLL
- Lymphoma, Small Lymphocytic
- Lymphocytic Lymphoma, Small
- Lymphocytic Lymphomas, Small
- Lymphomas, Small Lymphocytic
- Small Lymphocytic Lymphoma
- Small Lymphocytic Lymphomas
- Lymphoma, Small Lymphocytic, Plasmacytoid
- Lymphoma, Small-Cell
- Lymphoma, Small Cell
- Lymphomas, Small-Cell
- Small-Cell Lymphomas
- Lymphoplasmacytoid Lymphoma, CLL
- CLL Lymphoplasmacytoid Lymphoma
- CLL Lymphoplasmacytoid Lymphomas
- Lymphoma, CLL Lymphoplasmacytoid
- Lymphomas, CLL Lymphoplasmacytoid
- Lymphoplasmacytoid Lymphomas, CLL
- Small-Cell Lymphoma
- Small Cell Lymphoma
- Lymphoblastic Leukemia, Chronic
- Chronic Lymphoblastic Leukemia
- Chronic Lymphoblastic Leukemias
- Leukemias, Chronic Lymphoblastic
- Lymphoblastic Leukemias, Chronic
- Lymphocytic Leukemia, Chronic
- Lymphocytic Leukemia, Chronic, B Cell
- Lymphocytic Leukemia, Chronic, B-Cell
- Lymphocytic Lymphoma
- Lymphocytic Lymphomas
- Lymphomas, Lymphocytic
- Lymphocytic Lymphoma, Diffuse, Well Differentiated
- Lymphocytic Lymphoma, Diffuse, Well-Differentiated
- Lymphocytic Lymphoma, Well Differentiated
- Lymphocytic Lymphoma, Well-Differentiated
- Lymphocytic Lymphomas, Well-Differentiated
- Lymphoma, Well-Differentiated Lymphocytic
- Lymphomas, Well-Differentiated Lymphocytic
- Well-Differentiated Lymphocytic Lymphoma
- Well-Differentiated Lymphocytic Lymphomas
- Lymphoma, Lymphocytic
- Lymphoma, Lymphocytic, Diffuse, Well Differentiated
- B-Cell Chronic Lymphocytic Leukemia
- B Cell Chronic Lymphocytic Leukemia
- B-Cell Leukemia, Chronic
- B Cell Leukemia, Chronic
- B-Cell Leukemias, Chronic
- Chronic B-Cell Leukemia
- Chronic B-Cell Leukemias
- Leukemia, Chronic B-Cell
- Leukemias, Chronic B-Cell
- B-Cell Malignancy, Low-Grade
- B-Lymphocytic Leukemia, Chronic
- B Lymphocytic Leukemia, Chronic
- B-Lymphocytic Leukemias, Chronic
- Chronic B-Lymphocytic Leukemia
- Chronic B-Lymphocytic Leukemias
- Leukemia, Chronic B-Lymphocytic
- Leukemias, Chronic B-Lymphocytic
- Chronic Lymphocytic Leukemia
- Chronic Lymphocytic Leukemias
- Lymphocytic Leukemias, Chronic
- Diffuse Well-Differentiated Lymphocytic Lymphoma
- Diffuse Well Differentiated Lymphocytic Lymphoma
- Disrupted In B-Cell Malignancy
- Leukemia, B Cell, Chronic
- Leukemia, B-Cell, Chronic
- Leukemia, Chronic Lymphatic
- Leukemia, Chronic Lymphocytic
- Leukemia, Chronic Lymphocytic, B-Cell
- Leukemia, Lymphoblastic, Chronic
- Leukemia, Lymphocytic, Chronic
- Lymphoma, Lymphocytic, Diffuse, Well-Differentiated
- Lymphoma, Lymphocytic, Well Differentiated
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Lymphocytic, Chronic, B-Cell".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Leukemia [C04.557.337]
- Leukemia, Lymphoid [C04.557.337.428]
- Leukemia, B-Cell [C04.557.337.428.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C04.557.337.428.080.125]
- Hemic and Lymphatic Diseases [C15]
- Lymphatic Diseases [C15.604]
- Lymphoproliferative Disorders [C15.604.515]
- Leukemia, Lymphoid [C15.604.515.560]
- Leukemia, B-Cell [C15.604.515.560.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C15.604.515.560.080.125]
- Immune System Diseases [C20]
- Immunoproliferative Disorders [C20.683]
- Lymphoproliferative Disorders [C20.683.515]
- Leukemia, Lymphoid [C20.683.515.528]
- Leukemia, B-Cell [C20.683.515.528.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C20.683.515.528.080.125]
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Lymphocytic, Chronic, B-Cell".
This graph shows the total number of publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in this website by year, and whether "Leukemia, Lymphocytic, Chronic, B-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2015 | 3 | 0 | 3 | | 2017 | 5 | 0 | 5 | | 2018 | 1 | 0 | 1 | | 2019 | 7 | 0 | 7 | | 2020 | 5 | 0 | 5 | | 2021 | 6 | 0 | 6 | | 2022 | 8 | 0 | 8 | | 2023 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in Profiles.
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Randall J, Evans K, Watts B, Smith CM, Hughes K, Earley EJ, Erickson SW, Pachter JA, Teicher BA, Smith MA, Lock RB. In vivo activity of the dual PI3Kd and PI3K? inhibitor duvelisib against pediatric acute lymphoblastic leukemia xenografts. Pediatr Blood Cancer. 2023 Aug; 70(8):e30398.
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Gupta S, Dai Y, Chen Z, Winestone LE, Teachey DT, Bona K, Aplenc R, Rabin KR, Zweidler-McKay P, Carroll AJ, Heerema NA, Gastier-Foster J, Borowitz MJ, Wood BL, Maloney KW, Mattano LA, Larsen EC, Angiolillo AL, Burke MJ, Salzer WL, Winter SS, Brown PA, Guest EM, Dunsmore KP, Kairalla JA, Winick NJ, Carroll WL, Raetz EA, Hunger SP, Loh ML, Devidas M. Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia: secondary analyses of eight Children's Oncology Group cohort trials. Lancet Haematol. 2023 Feb; 10(2):e129-e141.
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Kent A, Pollyea DA. Top advances of the year: Leukemia. Cancer. 2023 04 01; 129(7):981-985.
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Askow AT, Paulussen KJM, McKenna CF, Salvador AF, Scaroni SE, Hamann JS, Ulanov AV, Li Z, Paluska SA, Beaudry KM, De Lisio M, Burd NA. Creatine Monohydrate Supplementation, but not Creatyl-L-Leucine, Increased Muscle Creatine Content in Healthy Young Adults: A Double-Blind Randomized Controlled Trial. Int J Sport Nutr Exerc Metab. 2022 Nov 01; 32(6):446-452.
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Thompson MC, Harrup RA, Coombs CC, Roeker LE, Pu JJ, Choi MY, Barr PM, Allan JN, ?imkovic M, Leslie L, Rhodes J, Chong EA, Kamdar M, Skarbnik A, Lansigan F, McCall B, Saja K, Dyer MJS, Walter HS, Lefebure M, Thadani-Mulero M, Boyer M, Biondo J, Sail K, Manzoor BS, Furman R, Bantilan KS, Goy A, Feldman T, Labella D, Schuster SJ, Park J, Palomba L, Zelenetz A, Eyre TA, Kater AP, Seymour JF, Mato AR. Venetoclax retreatment of patients with chronic lymphocytic leukemia after a previous venetoclax-based regimen. Blood Adv. 2022 08 09; 6(15):4553-4557.
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Li A, Ambruso SL, Oto OA, Barry M, Edelstein CL. A case report of pre-eclampsia-like endothelial injury in the kidney of an 85-year-old man treated with ibrutinib. BMC Nephrol. 2022 07 23; 23(1):264.
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Smith AL, Eiken AP, Skupa SA, Moore DY, Umeta LT, Smith LM, Lyden ER, D'Angelo CR, Kallam A, Vose JM, Kutateladze TG, El-Gamal D. A Novel Triple-Action Inhibitor Targeting B-Cell Receptor Signaling and BRD4 Demonstrates Preclinical Activity in Chronic Lymphocytic Leukemia. Int J Mol Sci. 2022 Jun 16; 23(12).
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Wierda WG, Brown J, Abramson JS, Awan F, Bilgrami SF, Bociek G, Brander D, Chanan-Khan AA, Coutre SE, Davis RS, Eradat H, Fletcher CD, Gaballa S, Ghobadi A, Hamid MS, Hernandez-Ilizaliturri F, Hill B, Kaesberg P, Kamdar M, Kaplan LD, Khan N, Kipps TJ, Ma S, Mato A, Mosse C, Schuster S, Siddiqi T, Stephens DM, Ujjani C, Wagner-Johnston N, Woyach JA, Ye JC, Dwyer MA, Sundar H. NCCN Guidelines? Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 3.2022. J Natl Compr Canc Netw. 2022 06; 20(6):622-634.
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Poppova L, Pavlova S, Gonzalez B, Kotaskova J, Plevova K, Dumbovic G, Janovska P, Bystry V, Panovska A, Bezdekova L, Maslejova S, Brychtova Y, Doubek M, Krzyzankova M, Borsky M, Mayer J, Bryja V, Alonso S, Pospisilova S. Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene. Epigenetics. 2022 Dec; 17(12):1628-1635.
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Wang E, Mi X, Thompson MC, Montoya S, Notti RQ, Afaghani J, Durham BH, Penson A, Witkowski MT, Lu SX, Bourcier J, Hogg SJ, Erickson C, Cui D, Cho H, Singer M, Totiger TM, Chaudhry S, Geyer M, Alencar A, Linley AJ, Palomba ML, Coombs CC, Park JH, Zelenetz A, Roeker L, Rosendahl M, Tsai DE, Ebata K, Brandhuber B, Hyman DM, Aifantis I, Mato A, Taylor J, Abdel-Wahab O. Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors. N Engl J Med. 2022 02 24; 386(8):735-743.
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