 Receptors, Antigen, B-Cell
"Receptors, Antigen, B-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
IMMUNOGLOBULINS on the surface of B-LYMPHOCYTES. Their MESSENGER RNA contains an EXON with a membrane spanning sequence, producing immunoglobulins in the form of type I transmembrane proteins as opposed to secreted immunoglobulins (ANTIBODIES) which do not contain the membrane spanning segment.
| Descriptor ID |
D011947
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| MeSH Number(s) |
D12.776.124.790.651.950 D12.776.377.715.548.950 D12.776.543.750.705.816.821
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| Concept/Terms |
Receptors, Antigen, B-Cell- Receptors, Antigen, B-Cell
- Membrane Bound Immunoglobulin
- Bound Immunoglobulin, Membrane
- Immunoglobulin, Membrane Bound
- Membrane-Bound Immunoglobulins
- Membrane Bound Immunoglobulins
- B-Cell Antigen Receptors
- B Cell Antigen Receptors
- Immunoglobulins, Surface
- Receptors, Antigen, B Cell
- Antigen Receptors, B-Cell
- Antigen Receptors, B Cell
- Receptors, B-Cell Antigen
- Immunoglobulins, Membrane-Bound
- Immunoglobulins, Membrane Bound
- Surface Immunoglobulins
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Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, B-Cell".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Blood Proteins [D12.776.124]
- Serum Globulins [D12.776.124.790]
- Immunoglobulins [D12.776.124.790.651]
- Receptors, Antigen, B-Cell [D12.776.124.790.651.950]
- Globulins [D12.776.377]
- Serum Globulins [D12.776.377.715]
- Immunoglobulins [D12.776.377.715.548]
- Receptors, Antigen, B-Cell [D12.776.377.715.548.950]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Antigen [D12.776.543.750.705.816]
- Receptors, Antigen, B-Cell [D12.776.543.750.705.816.821]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, B-Cell".
This graph shows the total number of publications written about "Receptors, Antigen, B-Cell" by people in this website by year, and whether "Receptors, Antigen, B-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 6 | 0 | 6 | | 1991 | 6 | 0 | 6 | | 1992 | 4 | 1 | 5 | | 1993 | 4 | 0 | 4 | | 1994 | 6 | 1 | 7 | | 1995 | 5 | 0 | 5 | | 1996 | 1 | 1 | 2 | | 1997 | 8 | 0 | 8 | | 1998 | 5 | 0 | 5 | | 1999 | 4 | 1 | 5 | | 2000 | 3 | 5 | 8 | | 2001 | 3 | 2 | 5 | | 2002 | 6 | 0 | 6 | | 2003 | 1 | 1 | 2 | | 2004 | 3 | 2 | 5 | | 2005 | 4 | 0 | 4 | | 2006 | 3 | 5 | 8 | | 2007 | 4 | 3 | 7 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 1 | 3 | | 2010 | 2 | 2 | 4 | | 2011 | 3 | 1 | 4 | | 2012 | 1 | 3 | 4 | | 2013 | 3 | 1 | 4 | | 2014 | 4 | 3 | 7 | | 2015 | 1 | 2 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 3 | 5 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Antigen, B-Cell" by people in Profiles.
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Walker MM, Crute BW, Cambier JC, Getahun A. B Cell-Intrinsic STING Signaling Triggers Cell Activation, Synergizes with B Cell Receptor Signals, and Promotes Antibody Responses. J Immunol. 2018 11 01; 201(9):2641-2653.
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Sang A, Danhorn T, Peterson JN, Rankin AL, O'Connor BP, Leach SM, Torres RM, Pelanda R. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nat Commun. 2018 09 28; 9(1):3973.
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Hobeika E, Dautzenberg M, Levit-Zerdoun E, Pelanda R, Reth M. Conditional Selection of B Cells in Mice With an Inducible B Cell Development. Front Immunol. 2018; 9:1806.
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Greaves SA, Peterson JN, Torres RM, Pelanda R. Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Front Immunol. 2018; 9:707.
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Franks SE, Cambier JC. Putting on the Brakes: Regulatory Kinases and Phosphatases Maintaining B Cell Anergy. Front Immunol. 2018; 9:665.
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Getahun A, Wemlinger SM, Rudra P, Santiago ML, van Dyk LF, Cambier JC. Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway. J Exp Med. 2017 04 03; 214(4):931-941.
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Seay HR, Yusko E, Rothweiler SJ, Zhang L, Posgai AL, Campbell-Thompson M, Vignali M, Emerson RO, Kaddis JS, Ko D, Nakayama M, Smith MJ, Cambier JC, Pugliese A, Atkinson MA, Robins HS, Brusko TM. Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes. JCI Insight. 2016 12 08; 1(20):e88242.
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Lang J, Ota T, Kelly M, Strauch P, Freed BM, Torres RM, Nemazee D, Pelanda R. Receptor editing and genetic variability in human autoreactive B cells. J Exp Med. 2016 Jan 11; 213(1):93-108.
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Akerlund J, Getahun A, Cambier JC. B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens. J Autoimmun. 2015 Aug; 62:45-54.
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Hobeika E, Levit-Zerdoun E, Anastasopoulou V, Pohlmeyer R, Altmeier S, Alsadeq A, Dobenecker MW, Pelanda R, Reth M. CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. EMBO J. 2015 Apr 01; 34(7):925-39.
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