Lamin Type A
"Lamin Type A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to disassociate from nuclear membranes during mitosis.
Descriptor ID |
D034904
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MeSH Number(s) |
D12.776.660.650.875.500
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Concept/Terms |
Lamin Type A- Lamin Type A
- Lamin A
- Type A Lamins
- Lamins, Type A
- Lamin A-C
- Lamin A C
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Below are MeSH descriptors whose meaning is more general than "Lamin Type A".
Below are MeSH descriptors whose meaning is more specific than "Lamin Type A".
This graph shows the total number of publications written about "Lamin Type A" by people in this website by year, and whether "Lamin Type A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2007 | 0 | 2 | 2 | 2008 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 | 2015 | 2 | 1 | 3 | 2016 | 0 | 1 | 1 | 2018 | 1 | 0 | 1 | 2019 | 4 | 0 | 4 | 2020 | 2 | 1 | 3 | 2021 | 2 | 1 | 3 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lamin Type A" by people in Profiles.
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Sidhu K, Castrini AI, Parikh V, Reza N, Owens A, Tremblay-Gravel M, Wheeler MT, Mestroni L, Taylor M, Graw S, Gigli M, Merlo M, Paldino A, Sinagra G, Judge DP, Ramos H, Mesubi O, Brown E, Turnbull S, Kumar S, Roy D, Tedrow UB, Ngo L, Haugaa K, Lakdawala NK. The response to cardiac resynchronization therapy in LMNA cardiomyopathy. Eur J Heart Fail. 2022 04; 24(4):685-693.
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Gao S, Mumme-Monheit A, Chen SN, Spector EB, Slavov D, Baralle FE, Bristow MR, Mestroni L, Taylor MRG. An LMNA synonymous variant associated with severe dilated cardiomyopathy: Case report. Am J Med Genet A. 2022 02; 188(2):600-605.
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Rouhi L, Cheedipudi SM, Chen SN, Fan S, Lombardi R, Chen X, Coarfa C, Robertson MJ, Gurha P, Marian AJ. Haploinsufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a late-onset senescence-associated pro-fibrotic cardiomyopathy. Cardiovasc Res. 2021 09 28; 117(11):2377-2394.
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Lachaize V, Peña B, Ciubotaru C, Cojoc D, Chen SN, Taylor MRG, Mestroni L, Sbaizero O. Compromised Biomechanical Properties, Cell-Cell Adhesion and Nanotubes Communication in Cardiac Fibroblasts Carrying the Lamin A/C D192G Mutation. Int J Mol Sci. 2021 Aug 25; 22(17).
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Coste Pradas J, Auguste G, Matkovich SJ, Lombardi R, Chen SN, Garnett T, Chamberlain K, Riyad JM, Weber T, Singh SK, Robertson MJ, Coarfa C, Marian AJ, Gurha P. Identification of Genes and Pathways Regulated by Lamin A in Heart. J Am Heart Assoc. 2020 08 18; 9(16):e015690.
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Malik F, Santiago T, Newman S, McCarville B, Pappo AS, Clay MR. An addition to the evolving spectrum of lipofibromatosis and lipofibromatosis-like neural tumor: Molecular findings in an unusual phenotype aid in accurate classification. Pathol Res Pract. 2020 Jun; 216(6):152942.
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Borin D, Peña B, Taylor MRG, Mestroni L, Lapasin R, Sbaizero O. Viscoelastic behavior of cardiomyocytes carrying LMNA mutations. Biorheology. 2020; 57(1):1-14.
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Chen SN, Sbaizero O, Taylor MRG, Mestroni L. Lamin A/C Cardiomyopathy: Implications for Treatment. Curr Cardiol Rep. 2019 11 26; 21(12):160.
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Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, Rhee JW, Churko JM, Chaudhary R, Chour T, Wang PJ, Snyder MP, Chang HY, Karakikes I, Wu JC. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. 2019 08; 572(7769):335-340.
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Cheedipudi SM, Matkovich SJ, Coarfa C, Hu X, Robertson MJ, Sweet M, Taylor M, Mestroni L, Cleveland J, Willerson JT, Gurha P, Marian AJ. Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes Is Associated With Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy. Circ Res. 2019 04 12; 124(8):1198-1213.
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