Cyclin A
"Cyclin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that has specificity for CDC2 PROTEIN KINASE and CYCLIN-DEPENDENT KINASE 2. It plays a role in progression of the CELL CYCLE through G1/S and G2/M phase transitions.
Descriptor ID |
D019925
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MeSH Number(s) |
D12.644.360.262.100 D12.776.167.218.100 D12.776.476.262.100
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Concept/Terms |
Cyclin A- Cyclin A
- Type A Cyclin
- Cyclin, Type A
- Type A Cyclins
- Cyclins, Type A
- Adenovirus E1A-Associated Protein p60
- Adenovirus E1A Associated Protein p60
- E1A p60
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Below are MeSH descriptors whose meaning is more general than "Cyclin A".
Below are MeSH descriptors whose meaning is more specific than "Cyclin A".
This graph shows the total number of publications written about "Cyclin A" by people in this website by year, and whether "Cyclin A" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 2001 | 2 | 0 | 2 | 2002 | 0 | 1 | 1 | 2004 | 1 | 0 | 1 | 2005 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2010 | 1 | 1 | 2 | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin A" by people in Profiles.
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Pascreau G, Churchill ME, Maller JL. Centrosomal localization of cyclins E and A: structural similarities and functional differences. Cell Cycle. 2011 Jan 15; 10(2):199-205.
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Lambert JR, Eddy VJ, Young CD, Persons KS, Sarkar S, Kelly JA, Genova E, Lucia MS, Faller DV, Ray R. A vitamin D receptor-alkylating derivative of 1a,25-dihydroxyvitamin D3 inhibits growth of human kidney cancer cells and suppresses tumor growth. Cancer Prev Res (Phila). 2010 Dec; 3(12):1596-607.
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Ferguson RL, Pascreau G, Maller JL. The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication. J Cell Sci. 2010 Aug 15; 123(Pt 16):2743-9.
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Pascreau G, Eckerdt F, Churchill ME, Maller JL. Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):2932-7.
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McCoy EL, Kawakami K, Ford HL, Coletta RD. Expression of Six1 homeobox gene during development of the mouse submandibular salivary gland. Oral Dis. 2009 Sep; 15(6):407-13.
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Coletta RD, Christensen KL, Micalizzi DS, Jedlicka P, Varella-Garcia M, Ford HL. Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation. Cancer Res. 2008 Apr 01; 68(7):2204-13.
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Salabat MR, Ding XZ, Flesche JB, Ujiki MB, Robin TP, Talamonti MS, Bell RH, Adrian TE. On the mechanisms of 12-O-tetradecanoylphorbol-13-acetate-induced growth arrest in pancreatic cancer cells. Pancreas. 2006 Aug; 33(2):148-55.
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Pappa A, Brown D, Koutalos Y, DeGregori J, White C, Vasiliou V. Human aldehyde dehydrogenase 3A1 inhibits proliferation and promotes survival of human corneal epithelial cells. J Biol Chem. 2005 Jul 29; 280(30):27998-8006.
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Coletta RD, Christensen K, Reichenberger KJ, Lamb J, Micomonaco D, Huang L, Wolf DM, M?ller-Tidow C, Golub TR, Kawakami K, Ford HL. The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6478-83.
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Selzman CH, Miller SA, Zimmerman MA, Gamboni-Robertson F, Harken AH, Banerjee A. Monocyte chemotactic protein-1 directly induces human vascular smooth muscle proliferation. Am J Physiol Heart Circ Physiol. 2002 Oct; 283(4):H1455-61.
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