 Mast Cells
"Mast Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.
| Descriptor ID |
D008407
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| MeSH Number(s) |
A11.329.427 A15.382.652
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| Concept/Terms |
Mast Cells- Mast Cells
- Cell, Mast
- Cells, Mast
- Mast Cell
- Basophils, Tissue
- Basophil, Tissue
- Tissue Basophil
- Tissue Basophils
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Below are MeSH descriptors whose meaning is more general than "Mast Cells".
Below are MeSH descriptors whose meaning is more specific than "Mast Cells".
This graph shows the total number of publications written about "Mast Cells" by people in this website by year, and whether "Mast Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 | | 1996 | 4 | 1 | 5 | | 1997 | 2 | 0 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 2 | 0 | 2 | | 2000 | 2 | 0 | 2 | | 2001 | 2 | 0 | 2 | | 2003 | 4 | 0 | 4 | | 2004 | 2 | 1 | 3 | | 2006 | 0 | 1 | 1 | | 2007 | 2 | 3 | 5 | | 2008 | 0 | 4 | 4 | | 2009 | 2 | 3 | 5 | | 2011 | 0 | 2 | 2 | | 2012 | 2 | 2 | 4 | | 2013 | 4 | 2 | 6 | | 2014 | 4 | 2 | 6 | | 2015 | 2 | 0 | 2 | | 2016 | 2 | 2 | 4 | | 2017 | 3 | 1 | 4 | | 2018 | 2 | 1 | 3 | | 2019 | 3 | 1 | 4 | | 2020 | 3 | 1 | 4 | | 2021 | 3 | 1 | 4 | | 2022 | 0 | 2 | 2 | | 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Mast Cells" by people in Profiles.
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Gao J, Li Y, Guan X, Mohammed Z, Gomez G, Hui Y, Zhao D, Oskeritzian CA, Huang H. IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells. BMC Genomics. 2023 Oct 06; 24(1):592.
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Haque TT, Taruselli MT, Kee SA, Dailey JM, Pondicherry N, Gajewski-Kurdziel PA, Zellner MP, Stephenson DJ, MacKnight HP, Straus DB, Kankaria R, Jackson KG, Chumanevich AP, Fukuoka Y, Schwartz LB, Blakely RD, Oskeritzian CA, Chalfant CE, Martin RK, Ryan JJ. Fluoxetine restrains allergic inflammation by targeting an Fc?RI-ATP positive feedback loop in mast cells. Sci Signal. 2023 09 12; 16(802):eabc9089.
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Li Y, Qi X, Zhao D, Urban JF, Huang H. IL-3 Expands Pre-Basophil and Mast Cell Progenitors by Upregulating the IL-3 Receptor Expression. Cell Immunol. 2022 04; 374:104498.
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Zhang S, Shoda T, Aceves SS, Arva NC, Chehade M, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Khoury P, Leung J, Spergel AKR, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME. Mast cell-pain connection in eosinophilic esophagitis. Allergy. 2022 06; 77(6):1895-1899.
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Mendoza RP, Anderson CC, Fudge DH, Roede JR, Brown JM. Metabolic Consequences of IgE- and Non-IgE-Mediated Mast Cell Degranulation. J Immunol. 2021 12 01; 207(11):2637-2648.
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Cruz-Hernandez A, Mendoza RP, Nguyen K, Harder A, Evans CM, Bauer AK, Tewari-Singh N, Brown JM. Mast Cells Promote Nitrogen Mustard-Mediated Toxicity in the Lung Associated With Proinflammatory Cytokine and Bioactive Lipid Mediator Production. Toxicol Sci. 2021 10 27; 184(1):127-141.
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Zimmermann N, Abonia JP, Dreskin SC, Akin C, Bolton S, Happel CS, Geller M, Larenas-Linnemann D, Nanda A, Peterson K, Wasan A, Wechsler J, Zhang S, Bernstein JA. Developing a standardized approach for assessing mast cells and eosinophils on tissue biopsies: A?Work Group Report of the AAAAI Allergic Skin Diseases Committee. J Allergy Clin Immunol. 2021 10; 148(4):964-983.
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Mendoza RP, Fudge DH, Brown JM. Cellular Energetics of Mast Cell Development and Activation. Cells. 2021 03 02; 10(3).
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Li Y, Gao J, Kamran M, Harmacek L, Danhorn T, Leach SM, O'Connor BP, Hagman JR, Huang H. GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers. Nat Commun. 2021 01 21; 12(1):494.
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Nelson M, Zhang X, Genta RM, Turner K, Podgaetz E, Paris S, Cardenas J, Gu J, Leeds S, Ward M, Nguyen A, Konda V, Furuta GT, Pan Z, Souza RF, Spechler SJ. Lower esophageal sphincter muscle of patients with achalasia exhibits profound mast cell degranulation. Neurogastroenterol Motil. 2021 05; 33(5):e14055.
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