 Foramen Ovale, Patent
"Foramen Ovale, Patent" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.
| Descriptor ID |
D054092
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| MeSH Number(s) |
C14.240.400.560.375.258 C14.280.400.560.375.258 C16.131.240.400.560.375.258
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Foramen Ovale, Patent".
- Diseases [C]
- Cardiovascular Diseases [C14]
- Cardiovascular Abnormalities [C14.240]
- Heart Defects, Congenital [C14.240.400]
- Heart Septal Defects [C14.240.400.560]
- Heart Septal Defects, Atrial [C14.240.400.560.375]
- Foramen Ovale, Patent [C14.240.400.560.375.258]
- Heart Diseases [C14.280]
- Heart Defects, Congenital [C14.280.400]
- Heart Septal Defects [C14.280.400.560]
- Heart Septal Defects, Atrial [C14.280.400.560.375]
- Foramen Ovale, Patent [C14.280.400.560.375.258]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
- Cardiovascular Abnormalities [C16.131.240]
- Heart Defects, Congenital [C16.131.240.400]
- Heart Septal Defects [C16.131.240.400.560]
- Heart Septal Defects, Atrial [C16.131.240.400.560.375]
- Foramen Ovale, Patent [C16.131.240.400.560.375.258]
Below are MeSH descriptors whose meaning is more specific than "Foramen Ovale, Patent".
This graph shows the total number of publications written about "Foramen Ovale, Patent" by people in this website by year, and whether "Foramen Ovale, Patent" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2024 | 1 | 0 | 1 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Foramen Ovale, Patent" by people in Profiles.
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Pristipino C, Carroll J, Mas JL, Wunderlich NC, Sondergaard L. Treatment of patent foramen ovale. EuroIntervention. 2025 May 16; 21(10):505-524.
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Putaala J, Martinez-Majander N, Leppert M, Tulkki L, Pirinen J, Tolppanen H, Sarkanen T, Virtanen M, Jaakonm?ki N, J?k?l? P, Hedman M, Redfors P, Bech-Hanssen O, Junttola U, Huhtakangas J, Ylikotila P, Lautam?ki R, Schminke U, von Sarnowski B, Busch R, Yesilot N, Sezgin M, Waje-Andreassen U, Saeed S, Fonseca AC, Paula A, Amaya Pascasio L, Mart?nez-S?nchez P, K?rv J, Muda P, Ferdinand P, Oxley C, Zakarkaite D, Ryli?kiene K, Pezzini A, Lombardi CM, L?cen?k R, Zedde M, Grimaldi T, Tsivgoulis G, Sinisalo J, Gerdts E, Tatlisumak T. Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale. Stroke. 2025 Jun; 56(6):1428-1440.
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Shah AH, Horlick EM, Kass M, Carroll JD, Krasuski RA. The pathophysiology of patent foramen ovale and its related complications. Am Heart J. 2024 Nov; 277:76-92.
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Wang AY, Rothwell PM, Nelson J, Saver JL, Kasner SE, Carroll J, Mas JL, Derumeaux G, Chatellier G, Furlan AJ, Herrmann HC, J?ni P, Kim JS, Koethe B, Lee PH, Lefebvre B, Mattle HP, Meier B, Reisman M, Smalling RW, Sondergaard L, Song JK, Di Angelantonio E, DiTullio M, Elkind MSV, Homma S, Jaigobin C, Michel P, Mono ML, Nedeltchev K, Papetti F, Serena J, Weimar C, Li L, Mazzucco S, Silver LE, van Klaveren D, Thaler DE, Kent DM. Patent Foramen Ovale Closure in Older Patients With Stroke: Patient Selection for Trial Feasibility. Neurology. 2024 May 28; 102(10):e209388.
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Orjuela KD, Leppert MH, Carroll JD. Navigating the Gray: The Complex Story of PFO Closure Utilization. Circ Cardiovasc Qual Outcomes. 2024 01; 17(1):e010581.
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Poisson SN, Leppert MH, Orjuela KD. Cryptogenic Stroke and PFO Closure: Does Sex Matter? J Am Heart Assoc. 2023 10 03; 12(19):e031857.
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Guo ZN, Qu Y, Gao Y, Xing Y, Ma H, Liu J, Guo YZ, Chang J, Zhang P, Jin H, Sun X, Han K, Hu HH, He Q, Simpson DM, Yang Y. Changes in cerebral autoregulation, stroke-related blood biomarkers, and autonomic regulation after patent foramen ovale closure in severe migraine patients. CNS Neurosci Ther. 2023 10; 29(10):3031-3042.
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Mas JL, Saver JL, Kasner SE, Nelson J, Carroll JD, Chatellier G, Derumeaux G, Furlan AJ, Herrmann HC, J?ni P, Kim JS, Koethe B, Lee PH, Lefebvre B, Mattle HP, Meier B, Reisman M, Smalling RW, Sondergaard L, Song JK, Thaler DE, Kent DM. Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure. JAMA Neurol. 2022 11 01; 79(11):1175-1179.
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Kent DM, Saver JL, Kasner SE, Nelson J, Carroll JD, Chatellier G, Derumeaux G, Furlan AJ, Herrmann HC, J?ni P, Kim JS, Koethe B, Lee PH, Lefebvre B, Mattle HP, Meier B, Reisman M, Smalling RW, Soendergaard L, Song JK, Mas JL, Thaler DE. Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke. JAMA. 2021 12 14; 326(22):2277-2286.
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Pelayo J, Shahzad A, Peterson E, Pressman G. Platypnea-orthodeoxia syndrome in patent foramen ovale and fenestrated atrial septal aneurysm with normal right atrial pressure: what is the culprit? BMJ Case Rep. 2021 Jul 01; 14(7).
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