 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 2 | 1 | 3 | | 1990 | 3 | 1 | 4 | | 1991 | 1 | 0 | 1 | | 1992 | 4 | 0 | 4 | | 1993 | 2 | 0 | 2 | | 1994 | 1 | 0 | 1 | | 1995 | 6 | 0 | 6 | | 1996 | 1 | 0 | 1 | | 1997 | 6 | 0 | 6 | | 1998 | 6 | 0 | 6 | | 1999 | 3 | 1 | 4 | | 2000 | 6 | 2 | 8 | | 2001 | 6 | 1 | 7 | | 2002 | 7 | 1 | 8 | | 2003 | 6 | 1 | 7 | | 2004 | 7 | 1 | 8 | | 2005 | 2 | 3 | 5 | | 2007 | 7 | 1 | 8 | | 2008 | 12 | 3 | 15 | | 2009 | 9 | 2 | 11 | | 2010 | 8 | 1 | 9 | | 2011 | 14 | 3 | 17 | | 2012 | 9 | 3 | 12 | | 2013 | 8 | 0 | 8 | | 2014 | 14 | 1 | 15 | | 2015 | 12 | 2 | 14 | | 2016 | 12 | 2 | 14 | | 2017 | 27 | 0 | 27 | | 2018 | 3 | 1 | 4 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Hollenbach JA, Norman PJ, Creary LE, Damotte V, Montero-Martin G, Caillier S, Anderson KM, Misra MK, Nemat-Gorgani N, Osoegawa K, Santaniello A, Renschen A, Marin WM, Dandekar R, Parham P, Tanner CM, Hauser SL, Fernandez-Viña M, Oksenberg JR. A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease. Proc Natl Acad Sci U S A. 2019 04 09; 116(15):7419-7424.
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Winter M, Costabile JD, Abosch A, Thompson JA. Method for localizing intraoperative recordings from deep brain stimulation surgery using post-operative structural MRI. Neuroimage Clin. 2018; 20:1123-1128.
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Lesteberg KE, Beckham JD. Immunology of West Nile Virus Infection and the Role of Alpha-Synuclein as a Viral Restriction Factor. Viral Immunol. 2019 Jan/Feb; 32(1):38-47.
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Telkes I, Viswanathan A, Jimenez-Shahed J, Abosch A, Ozturk M, Gupte A, Jankovic J, Ince NF. Local field potentials of subthalamic nucleus contain electrophysiological footprints of motor subtypes of Parkinson's disease. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):E8567-E8576.
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Crowley S, Huang H, Tanner J, Zhao Q, Schwab NA, Hizel L, Ramon D, Brumback B, Ding M, Price CC. Considering total intracranial volume and other nuisance variables in brain voxel based morphometry in idiopathic PD. Brain Imaging Behav. 2018 02; 12(1):1-12.
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Zhuang X, Walsh RR, Sreenivasan K, Yang Z, Mishra V, Cordes D. Incorporating spatial constraint in co-activation pattern analysis to explore the dynamics of resting-state networks: An application to Parkinson's disease. Neuroimage. 2018 05 15; 172:64-84.
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Zhou W, Barkow JC, Freed CR. Running wheel exercise reduces a-synuclein aggregation and improves motor and cognitive function in a transgenic mouse model of Parkinson's disease. PLoS One. 2017; 12(12):e0190160.
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Fullard ME, Thibault DP, Todaro V, Foster S, Katz L, Morgan R, Kern DS, Schwalb JM, Urrea Mendoza E, Dahodwala N, Shulman L, Willis AW. Sex disparities in health and health care utilization after Parkinson diagnosis: Rethinking PD associated disability. Parkinsonism Relat Disord. 2018 03; 48:45-50.
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Mills KA, Greene MC, Dezube R, Goodson C, Karmarkar T, Pontone GM. Efficacy and tolerability of antidepressants in Parkinson's disease: A systematic review and network meta-analysis. Int J Geriatr Psychiatry. 2018 04; 33(4):642-651.
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Schonhaut DR, McMillan CT, Spina S, Dickerson BC, Siderowf A, Devous MD, Tsai R, Winer J, Russell DS, Litvan I, Roberson ED, Seeley WW, Grinberg LT, Kramer JH, Miller BL, Pressman P, Nasrallah I, Baker SL, Gomperts SN, Johnson KA, Grossman M, Jagust WJ, Boxer AL, Rabinovici GD. 18 F-flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study. Ann Neurol. 2017 Oct; 82(4):622-634.
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