 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1995 | 6 | 0 | 6 | | 1997 | 4 | 0 | 4 | | 1998 | 2 | 0 | 2 | | 1999 | 2 | 1 | 3 | | 2000 | 3 | 1 | 4 | | 2001 | 1 | 0 | 1 | | 2002 | 2 | 2 | 4 | | 2003 | 6 | 0 | 6 | | 2004 | 4 | 1 | 5 | | 2005 | 2 | 2 | 4 | | 2006 | 0 | 1 | 1 | | 2007 | 6 | 1 | 7 | | 2008 | 9 | 2 | 11 | | 2009 | 7 | 1 | 8 | | 2010 | 2 | 1 | 3 | | 2011 | 8 | 2 | 10 | | 2012 | 8 | 1 | 9 | | 2013 | 6 | 0 | 6 | | 2014 | 11 | 0 | 11 | | 2015 | 8 | 0 | 8 | | 2016 | 8 | 1 | 9 | | 2017 | 22 | 0 | 22 | | 2018 | 25 | 2 | 27 | | 2019 | 14 | 2 | 16 | | 2020 | 15 | 3 | 18 | | 2021 | 11 | 0 | 11 | | 2022 | 12 | 0 | 12 | | 2023 | 5 | 0 | 5 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Bhadra J, Sridhar N, Fajrial AK, Hammond N, Xue D, Ding X. Acoustic streaming enabled moderate swimming exercise reduces neurodegeneration in C. elegans. Sci Adv. 2023 02 22; 9(8):eadf5056.
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Heiden DL, Monogue B, Ali MDH, Beckham JD. A functional role for alpha-synuclein in neuroimmune responses. J Neuroimmunol. 2023 03 15; 376:578047.
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Gibbons C, Wang N, Rajan S, Kern D, Palma JA, Kaufmann H, Freeman R. Cutaneous a-Synuclein Signatures in Patients With Multiple System Atrophy and Parkinson Disease. Neurology. 2023 04 11; 100(15):e1529-e1539.
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Wylie KP, Kluger BM, Medina LD, Holden SK, Kronberg E, Tregellas JR, Buard I. Hippocampal, basal ganglia and olfactory connectivity contribute to cognitive impairments in Parkinson's disease. Eur J Neurosci. 2023 02; 57(3):511-526.
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Kennis M, Hale EW, Hemendinger E, Davis R, Ojemann SG, Strom L, Klepitskaya O. Suicide in Deep Brain Stimulation for Parkinson's Disease: A Retrospective Case-Control Study. J Parkinsons Dis. 2023; 13(3):415-419.
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Heronemus M, Hostetter TA, Smith AA, Forster JE, Brenner LA. Parkinson's disease and suicide among individuals seeking care within the United States Veterans Health Administration. Parkinsonism Relat Disord. 2022 Dec; 105:58-61.
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Tekriwal A, Baker S, Christensen E, Petersen-Jones H, Tien RN, Ojemann SG, Kern DS, Kramer DR, Felsen G, Thompson JA. Quantifying neuro-motor correlations during awake deep brain stimulation surgery using markerless tracking. Sci Rep. 2022 Oct 27; 12(1):18120.
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Baker S, Tekriwal A, Felsen G, Christensen E, Hirt L, Ojemann SG, Kramer DR, Kern DS, Thompson JA. Automatic extraction of upper-limb kinematic activity using deep learning-based markerless tracking during deep brain stimulation implantation for Parkinson's disease: A proof of concept study. PLoS One. 2022; 17(10):e0275490.
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Patterson CG, Joslin E, Gil AB, Spigle W, Nemet T, Chahine L, Christiansen CL, Melanson E, Kohrt WM, Mancini M, Josbeno D, Balfany K, Griffith G, Dunlap MK, Lamotte G, Suttman E, Larson D, Branson C, McKee KE, Goelz L, Poon C, Tilley B, Kang UJ, Tansey MG, Luthra N, Tanner CM, Haus JM, Fantuzzi G, McFarland NR, Gonzalez-Latapi P, Foroud T, Motl R, Schwarzschild MA, Simuni T, Marek K, Naito A, Lungu C, Corcos DM. Study in Parkinson's disease of exercise phase 3 (SPARX3): study protocol for a randomized controlled trial. Trials. 2022 Oct 06; 23(1):855.
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Choi ML, Chappard A, Singh BP, Maclachlan C, Rodrigues M, Fedotova EI, Berezhnov AV, De S, Peddie CJ, Athauda D, Virdi GS, Zhang W, Evans JR, Wernick AI, Zanjani ZS, Angelova PR, Esteras N, Vinokurov AY, Morris K, Jeacock K, Tosatto L, Little D, Gissen P, Clarke DJ, Kunath T, Collinson L, Klenerman D, Abramov AY, Horrocks MH, Gandhi S. Pathological structural conversion of a-synuclein at the mitochondria induces neuronal toxicity. Nat Neurosci. 2022 09; 25(9):1134-1148.
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