Liver Failure, Acute
"Liver Failure, Acute" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
Descriptor ID |
D017114
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MeSH Number(s) |
C06.552.308.500.750
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Concept/Terms |
Liver Failure, Acute- Liver Failure, Acute
- Failure, Acute Liver
- Fulminating Hepatic Failure
- Fulminating Hepatic Failures
- Hepatic Failure, Fulminating
- Hepatic Failures, Fulminating
- Liver Failure, Fulminant
- Fulminant Liver Failure
- Fulminant Liver Failures
- Liver Failures, Fulminant
- Hepatic Failure, Acute
- Acute Hepatic Failure
- Failure, Acute Hepatic
- Hepatic Failure, Fulminant
- Fulminant Hepatic Failure
- Fulminant Hepatic Failures
- Hepatic Failures, Fulminant
- Acute Liver Failure
- Fulminating Liver Failure
- Fulminating Liver Failures
- Liver Failure, Fulminating
- Liver Failures, Fulminating
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Below are MeSH descriptors whose meaning is more general than "Liver Failure, Acute".
Below are MeSH descriptors whose meaning is more specific than "Liver Failure, Acute".
This graph shows the total number of publications written about "Liver Failure, Acute" by people in this website by year, and whether "Liver Failure, Acute" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 | 1998 | 1 | 1 | 2 | 1999 | 1 | 0 | 1 | 2005 | 3 | 0 | 3 | 2006 | 5 | 0 | 5 | 2008 | 2 | 0 | 2 | 2009 | 4 | 1 | 5 | 2010 | 2 | 0 | 2 | 2011 | 1 | 0 | 1 | 2012 | 1 | 1 | 2 | 2013 | 3 | 1 | 4 | 2014 | 0 | 1 | 1 | 2015 | 1 | 1 | 2 | 2017 | 2 | 0 | 2 | 2018 | 1 | 1 | 2 | 2020 | 1 | 0 | 1 | 2021 | 1 | 0 | 1 | 2023 | 3 | 0 | 3 | 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Liver Failure, Acute" by people in Profiles.
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Rolfes PS, Sundaram SS, Sokol RJ, Taylor SA. Establishing Neonate-Specific Prognostic Markers in Acute Liver Failure: Admission Alpha Fetoprotein and Novel Neonatal Acute Liver Failure Scores Predict Patient Outcomes. J Pediatr. 2024 Sep; 272:114080.
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Ramachandran A, Akakpo JY, Curry SC, Rumack BH, Jaeschke H. Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure. Biochem Pharmacol. 2024 10; 228:116056.
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Squires JE, Miethke AG, Valencia CA, Hawthorne K, Henn L, Van Hove JLK, Squires RH, Bove K, Horslen S, Kohli R, Molleston JP, Romero R, Alonso EM, Bezerra JA, Guthery SL, Hsu E, Karpen SJ, Loomes KM, Ng VL, Rosenthal P, Mysore K, Wang KS, Friederich MW, Magee JC, Sokol RJ. Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children. Hepatol Commun. 2023 06 01; 7(6).
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Boster JM, Dominguez SR, Messacar K, Adams M, Weinberg A, Black JO, Feldman AG. Acute Liver Failure in a Child With Adenovirus Detected by PCR in the Explanted Liver. Pediatrics. 2023 02 01; 151(2).
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Goldhaber NH, Barnard Giustini A, Parekh J, Mekeel KL, Ajmera V. Acute Fulminant Hepatic Failure in 23-Year-Old Female Taking Homeopathic Remedy. J Investig Med High Impact Case Rep. 2023 Jan-Dec; 11:23247096231207480.
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Hirasawa Y, Yoshimura K, Matsui H, Kubota Y, Ishida H, Arai J, Sakaki M, Oguro N, Shida M, Taniguchi M, Hamada K, Ariizumi H, Ishiguro T, Ohkuma R, Sambe T, Horiike A, Imamura CK, Shiozawa E, Wada S, Tsurutani J, Iwamoto S, Uchida N, Kiuchi Y, Tate G, Kobayashi S, Tsunoda T. A case report on severe nivolumab-induced adverse events similar to primary sclerosing cholangitis refractory to immunosuppressive therapy. Medicine (Baltimore). 2021 Jun 11; 100(23):e25774.
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Kumar S, Lin S, Schold JD. Impact of donation after circulatory death donor allografts on outcomes following liver transplantation for fulminant hepatic failure in the United States. Am J Transplant. 2021 01; 21(1):382-390.
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Narkewicz MR, Horslen S, Hardison RM, Shneider BL, Rodriguez-Baez N, Alonso EM, Ng VL, Leonis MA, Loomes KM, Rudnick DA, Rosenthal P, Romero R, Subbarao GC, Li R, Belle SH, Squires RH. A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients. Clin Gastroenterol Hepatol. 2018 11; 16(11):1801-1810.e3.
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Brandehoff NP, Baker KA, Bonney CF, Ng PC, Schimmel J, Hoyte CO. Articles You May Have Missed. J Med Toxicol. 2018 06; 14(2):156-159.
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Narkewicz MR, Horslen S, Belle SH, Rudnick DA, Ng VL, Rosenthal P, Romero R, Loomes KM, Zhang S, Hardison RM, Squires RH. Prevalence and Significance of Autoantibodies in Children With Acute Liver Failure. J Pediatr Gastroenterol Nutr. 2017 02; 64(2):210-217.
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