 Serine
"Serine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
| Descriptor ID |
D012694
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| MeSH Number(s) |
D12.125.154.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Serine".
Below are MeSH descriptors whose meaning is more specific than "Serine".
This graph shows the total number of publications written about "Serine" by people in this website by year, and whether "Serine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 1 | 2 | | 1993 | 0 | 2 | 2 | | 1995 | 1 | 2 | 3 | | 1996 | 3 | 1 | 4 | | 1997 | 0 | 1 | 1 | | 1998 | 1 | 3 | 4 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 3 | 4 | | 2002 | 2 | 3 | 5 | | 2003 | 1 | 6 | 7 | | 2004 | 0 | 5 | 5 | | 2005 | 2 | 5 | 7 | | 2006 | 1 | 6 | 7 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 4 | 5 | | 2009 | 1 | 4 | 5 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 3 | 3 | | 2012 | 1 | 4 | 5 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 4 | 4 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2017 | 3 | 1 | 4 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 2 | 4 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serine" by people in Profiles.
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Swanson MA, Miller K, Young SP, Tong S, Ghaloul-Gonzalez L, Neira-Fresneda J, Schlichting L, Peck C, Gabel L, Friederich MW, Van Hove JLK. Cerebrospinal fluid amino acids glycine, serine, and threonine in nonketotic hyperglycinemia. J Inherit Metab Dis. 2022 07; 45(4):734-747.
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Vugmeyster L, Fai Au D, Smith MC, Ostrovsky D. Comparative Hydrophobic Core Dynamics Between Wild-Type Amyloid-ß Fibrils, Glutamate-3 Truncation, and Serine-8 Phosphorylation. Chemphyschem. 2022 02 04; 23(3):e202100709.
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Forero-Quintero LS, Raymond W, Handa T, Saxton MN, Morisaki T, Kimura H, Bertrand E, Munsky B, Stasevich TJ. Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene. Nat Commun. 2021 05 26; 12(1):3158.
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Fridman V, Zarini S, Sillau S, Harrison K, Bergman BC, Feldman EL, Reusch JEB, Callaghan BC. Altered plasma serine and 1-deoxydihydroceramide profiles are associated with diabetic neuropathy in type 2 diabetes and obesity. J Diabetes Complications. 2021 04; 35(4):107852.
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Seo H, Johnson GA, Bazer FW, Wu G, McLendon BA, Kramer AC. Cell-Specific Expression of Enzymes for Serine Biosynthesis and Glutaminolysis in Farm Animals. Adv Exp Med Biol. 2021; 1285:17-28.
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Vugmeyster L, Au DF, Ostrovsky D, Rickertsen DRL, Reed SM. Dynamics of Serine-8 Side-Chain in Amyloid-ß Fibrils and Fluorenylmethyloxycarbonyl Serine Amino Acid, Investigated by Solid-State Deuteron NMR. J Phys Chem B. 2020 06 11; 124(23):4723-4731.
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Panda AK, Chakraborty A, Nandi SK, Biswas A. The impact of different mutations at arginine141 on the structure, subunit exchange dynamics and chaperone activity of Hsp16.3. Proteins. 2020 06; 88(6):759-774.
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Fridman V, Suriyanarayanan S, Novak P, David W, Macklin EA, McKenna-Yasek D, Walsh K, Aziz-Bose R, Oaklander AL, Brown R, Hornemann T, Eichler F. Randomized trial of l-serine in patients with hereditary sensory and autonomic neuropathy type 1. Neurology. 2019 01 22; 92(4):e359-e370.
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Zambrano CA, Escobar D, Ramos-Santiago T, Bollinger I, Stitzel J. Serine residues in the a4 nicotinic acetylcholine receptor subunit regulate surface a4ß2* receptor expression and clustering. Biochem Pharmacol. 2019 01; 159:64-73.
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Mestre TA, Pont-Sunyer C, Kausar F, Visanji NP, Ghate T, Connolly BS, Gasca-Salas C, Kern DS, Jain J, Slow EJ, Faust-Socher A, Kasten M, Wadia PM, Zadikoff C, Kumar P, de Bie RM, Thomsen T, Lang AE, Schüle B, Klein C, Tolosa E, Marras C. Clustering of motor and nonmotor traits in leucine-rich repeat kinase 2 G2019S Parkinson's disease nonparkinsonian relatives: A multicenter family study. Mov Disord. 2018 Jul; 33(6):960-965.
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