 Protein Conformation
"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
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| MeSH Number(s) |
G02.111.570.820.709
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| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
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Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 8 | 8 | | 1992 | 0 | 13 | 13 | | 1993 | 4 | 10 | 14 | | 1994 | 0 | 10 | 10 | | 1995 | 1 | 4 | 5 | | 1996 | 2 | 17 | 19 | | 1997 | 3 | 19 | 22 | | 1998 | 4 | 17 | 21 | | 1999 | 4 | 15 | 19 | | 2000 | 0 | 19 | 19 | | 2001 | 1 | 29 | 30 | | 2002 | 0 | 30 | 30 | | 2003 | 3 | 28 | 31 | | 2004 | 1 | 26 | 27 | | 2005 | 2 | 29 | 31 | | 2006 | 4 | 29 | 33 | | 2007 | 0 | 22 | 22 | | 2008 | 2 | 22 | 24 | | 2009 | 6 | 30 | 36 | | 2010 | 1 | 23 | 24 | | 2011 | 1 | 21 | 22 | | 2012 | 1 | 29 | 30 | | 2013 | 2 | 32 | 34 | | 2014 | 2 | 26 | 28 | | 2015 | 0 | 25 | 25 | | 2016 | 2 | 24 | 26 | | 2017 | 2 | 29 | 31 | | 2018 | 2 | 33 | 35 | | 2019 | 1 | 17 | 18 | | 2020 | 0 | 16 | 16 | | 2021 | 0 | 14 | 14 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Schaub C, Lee P, Racho-Jansen A, Giovinazzo J, Terra N, Raper J, Thomson R. Coiled-coil binding of the leucine zipper domains of APOL1 is necessary for the open cation channel conformation. J Biol Chem. 2021 09; 297(3):101009.
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Klein BJ, Deshpande A, Cox KL, Xuan F, Zandian M, Barbosa K, Khanal S, Tong Q, Zhang Y, Zhang P, Sinha A, Bohlander SK, Shi X, Wen H, Poirier MG, Deshpande AJ, Kutateladze TG. The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations. Nat Commun. 2021 07 05; 12(1):4130.
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Schier AC, Taatjes DJ. Everything at once: cryo-EM yields remarkable insights into human RNA polymerase II transcription. Nat Struct Mol Biol. 2021 07; 28(7):540-543.
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Zandian M, Gonzalez Salguero N, Shannon MD, Purusottam RN, Theint T, Poirier MG, Jaroniec CP. Conformational Dynamics of Histone H3 Tails in Chromatin. J Phys Chem Lett. 2021 Jul 08; 12(26):6174-6181.
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Awad MM, Liu S, Rybkin II, Arbour KC, Dilly J, Zhu VW, Johnson ML, Heist RS, Patil T, Riely GJ, Jacobson JO, Yang X, Persky NS, Root DE, Lowder KE, Feng H, Zhang SS, Haigis KM, Hung YP, Sholl LM, Wolpin BM, Wiese J, Christiansen J, Lee J, Schrock AB, Lim LP, Garg K, Li M, Engstrom LD, Waters L, Lawson JD, Olson P, Lito P, Ou SI, Christensen JG, Jänne PA, Aguirre AJ. Acquired Resistance to KRASG12C Inhibition in Cancer. N Engl J Med. 2021 06 24; 384(25):2382-2393.
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Redzic JS, Lee E, Born A, Issaian A, Henen MA, Nichols PJ, Blue A, Hansen KC, D'Alessandro A, Vögeli B, Eisenmesser EZ. The Inherent Dynamics and Interaction Sites of the SARS-CoV-2 Nucleocapsid N-Terminal Region. J Mol Biol. 2021 07 23; 433(15):167108.
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Casalvieri KA, Matheson CJ, Warfield BM, Backos DS, Reigan P. N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors. Bioorg Med Chem. 2021 07 01; 41:116220.
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Morrison EA, Baweja L, Poirier MG, Wereszczynski J, Musselman CA. Nucleosome composition regulates the histone H3 tail conformational ensemble and accessibility. Nucleic Acids Res. 2021 05 07; 49(8):4750-4767.
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Kuatsjah E, Chan ACK, Katahira R, Haugen SJ, Beckham GT, Murphy MEP, Eltis LD. Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6. J Biol Chem. 2021 Jan-Jun; 296:100758.
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Broadwell LJ, Smallegan MJ, Rigby KM, Navarro-Arriola JS, Montgomery RL, Rinn JL, Leinwand LA. Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart. J Biol Chem. 2021 Jan-Jun; 296:100694.
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