 Protein Conformation
"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
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| MeSH Number(s) |
G02.111.570.820.709
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| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
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Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 3 | 4 | | 1996 | 2 | 9 | 11 | | 1997 | 2 | 16 | 18 | | 1998 | 5 | 17 | 22 | | 1999 | 3 | 13 | 16 | | 2000 | 0 | 11 | 11 | | 2001 | 0 | 18 | 18 | | 2002 | 0 | 28 | 28 | | 2003 | 2 | 25 | 27 | | 2004 | 0 | 21 | 21 | | 2005 | 3 | 28 | 31 | | 2006 | 5 | 26 | 31 | | 2007 | 0 | 20 | 20 | | 2008 | 3 | 21 | 24 | | 2009 | 5 | 28 | 33 | | 2010 | 1 | 19 | 20 | | 2011 | 3 | 17 | 20 | | 2012 | 1 | 26 | 27 | | 2013 | 2 | 29 | 31 | | 2014 | 1 | 24 | 25 | | 2015 | 0 | 25 | 25 | | 2016 | 2 | 27 | 29 | | 2017 | 1 | 26 | 27 | | 2018 | 2 | 30 | 32 | | 2019 | 1 | 21 | 22 | | 2020 | 0 | 18 | 18 | | 2021 | 1 | 23 | 24 | | 2022 | 0 | 4 | 4 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 6 | 6 | | 2025 | 0 | 3 | 3 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Briganti L, Annamalai AS, Bester SM, Wei G, Andino-Moncada JR, Singh SP, Kleinpeter AB, Tripathi M, Nguyen B, Radhakrishnan R, Singh PK, Greenwood J, Schope LI, Haney R, Huang S-W, Freed EO, Engelman AN, Francis AC, Kvaratskhelia M. Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir. mBio. 2025 May 14; 16(5):e0361324.
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Lee E, Tran N, Redzic JS, Singh H, Alamillo L, Holyoak T, Hamelberg D, Eisenmesser EZ. Identifying and controlling inactive and active conformations of a serine protease. Sci Adv. 2025 Apr 11; 11(15):eadu7447.
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Lietzke EE, Saeb D, Aldrich EC, Bruce KD, Sprenger KG. Synergistic reduction in interfacial flexibility of TREM2R47H and ApoE4 may underlie AD pathology. Alzheimers Dement. 2025 Apr; 21(4):e70120.
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Lee E, Redzic JS, Eisenmesser EZ. Evolutionary Adaptations in Biliverdin Reductase B: Insights into Coenzyme Dynamics and Catalytic Efficiency. Int J Mol Sci. 2024 Dec 10; 25(24).
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Licht JA, Berry SP, Gutierrez MA, Gaudet R. They all rock: A systematic comparison of conformational movements in LeuT-fold transporters. Structure. 2024 Sep 05; 32(9):1528-1543.e3.
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Briganti L, Manzine LR, de Mello Capetti CC, de Ara?jo EA, de Oliveira Arnoldi Pellegrini V, Guimaraes FEG, de Oliveira Neto M, Polikarpov I. Unravelling biochemical and structural features of Bacillus licheniformis GH5 mannanase using site-directed mutagenesis and high-resolution protein crystallography studies. Int J Biol Macromol. 2024 Aug; 274(Pt 2):133182.
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Anderson JW, Vaisar D, Jones DN, Pegram LM, Vigers GP, Chen H, Moffat JG, Ahn NG. Conformation selection by ATP-competitive inhibitors and allosteric communication in ERK2. Elife. 2024 Mar 27; 12.
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Jacobson DR, Perkins TT. Quantifying a light-induced energetic change in bacteriorhodopsin by force spectroscopy. Proc Natl Acad Sci U S A. 2024 Feb 13; 121(7):e2313818121.
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Mukherjee S, Douglas N, Jimenez R. Influence of Fluorescence Lifetime Selections and Conformational Flexibility on Brightness of FusionRed Variants. J Phys Chem Lett. 2024 Feb 15; 15(6):1644-1651.
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Song J, Gooding AR, Hemphill WO, Love BD, Robertson A, Yao L, Zon LI, North TE, Kasinath V, Cech TR. Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science. 2023 09 22; 381(6664):1331-1337.
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