 Receptors, Aryl Hydrocarbon
"Receptors, Aryl Hydrocarbon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
| Descriptor ID |
D018336
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| MeSH Number(s) |
D12.776.260.643.715 D12.776.826.209.715 D12.776.930.760
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| Concept/Terms |
Receptors, Aryl Hydrocarbon- Receptors, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptor
- Receptor, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptors
- Dioxin Receptor
- Receptor, Dioxin
- Dioxin Receptors
- Receptors, Dioxin
- Polyaromatic Hydrocarbon Receptors
- Polyaromatic Hydrocarbon Receptor
- Receptor, Polyaromatic Hydrocarbon
- Receptors, Polyaromatic Hydrocarbon
- TCDD Receptor
- Receptor, TCDD
- Receptors, TCDD
- TCDD Receptors
- AH Receptor
- Receptor, AH
- AH Receptors
- Receptors, AH
- Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
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Below are MeSH descriptors whose meaning is more general than "Receptors, Aryl Hydrocarbon".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Aryl Hydrocarbon".
This graph shows the total number of publications written about "Receptors, Aryl Hydrocarbon" by people in this website by year, and whether "Receptors, Aryl Hydrocarbon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 2 | 3 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 1 | 2 | | 2023 | 1 | 1 | 2 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Aryl Hydrocarbon" by people in Profiles.
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Eichenfield LF, Silverberg JI, Hebert AA, Boguniewicz M. Targeting the aryl hydrocarbon receptor as a strategy to expand the therapeutic armamentarium in atopic dermatitis. J Dermatolog Treat. 2024 Dec; 35(1):2300354.
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Silverberg JI, Boguniewicz M, Quintana FJ, Clark RA, Gross L, Hirano I, Tallman AM, Brown PM, Fredericks D, Rubenstein DS, McHale KA. Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A?clinical review. J Allergy Clin Immunol. 2024 Jul; 154(1):1-10.
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Dolly A, P?tgens SA, Thibaut MM, Neyrinck AM, de Castro GS, Galbert C, Lefevre C, Wyart E, Gomes SP, Gon?alves DC, Lanthier N, Baldin P, Huot JR, Bonetto A, Seelaender M, Delzenne NM, Sokol H, Bindels LB. Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 06; 14(3):1569-1582.
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Wang WL, Kasamatsu J, Joshita S, Gilfillan S, Di Luccia B, Panda SK, Kim DH, Desai P, Bando JK, Huang SC, Yomogida K, Hoshino H, Fukushima M, Jacobsen EA, Van Dyken SJ, Ruedl C, Cella M, Colonna M. The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4+ eosinophils unique to the small intestine. Proc Natl Acad Sci U S A. 2022 06 07; 119(23):e2204557119.
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Frank DN, Qiu Y, Cao Y, Zhang S, Lu L, Kofonow JM, Robertson CE, Liu Y, Wang H, Levens CL, Kuhn KA, Song J, Ramakrishnan VR, Lu SL. A dysbiotic microbiome promotes head and neck squamous cell carcinoma. Oncogene. 2022 Feb; 41(9):1269-1280.
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Gupta A, Sasse SK, Gruca MA, Sanford L, Dowell RD, Gerber AN. Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics. J Biol Chem. 2021 10; 297(4):101147.
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Williams AE, Watt J, Robertson LW, Gadupudi G, Osborn ML, Soares MJ, Iqbal K, Pedersen KB, Shankar K, Littleton S, Maimone C, Eti NA, Suva LJ, Ronis MJJ. Skeletal Toxicity of Coplanar Polychlorinated Biphenyl Congener 126 in the Rat Is Aryl Hydrocarbon Receptor Dependent. Toxicol Sci. 2020 05 01; 175(1):113-125.
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Ly M, Rentas S, Vujovic A, Wong N, Moreira S, Xu J, Holzapfel N, Bhatia S, Tran D, Minden MD, Draper JS, Hope KJ. Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance. Cancer Res. 2019 Nov 15; 79(22):5799-5811.
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Donovan MG, Selmin OI, Romagnolo DF. Aryl Hydrocarbon Receptor Diet and Breast Cancer Risk. Yale J Biol Med. 2018 06; 91(2):105-127.
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Li Y, Liu B, Harmacek L, Long Z, Liang J, Lukin K, Leach SM, O'Connor B, Gerber AN, Hagman J, Roers A, Finkelman FD, Huang H. The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis. J Allergy Clin Immunol. 2018 10; 142(4):1173-1184.
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