 Protein Isoforms
"Protein Isoforms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
| Descriptor ID |
D020033
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| MeSH Number(s) |
D12.776.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Isoforms".
Below are MeSH descriptors whose meaning is more specific than "Protein Isoforms".
This graph shows the total number of publications written about "Protein Isoforms" by people in this website by year, and whether "Protein Isoforms" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1999 | 1 | 7 | 8 | | 2000 | 2 | 10 | 12 | | 2001 | 0 | 16 | 16 | | 2002 | 1 | 10 | 11 | | 2003 | 2 | 12 | 14 | | 2004 | 0 | 15 | 15 | | 2005 | 2 | 17 | 19 | | 2006 | 2 | 16 | 18 | | 2007 | 0 | 7 | 7 | | 2008 | 2 | 17 | 19 | | 2009 | 0 | 10 | 10 | | 2010 | 1 | 10 | 11 | | 2011 | 3 | 11 | 14 | | 2012 | 0 | 16 | 16 | | 2013 | 0 | 7 | 7 | | 2014 | 0 | 8 | 8 | | 2015 | 1 | 10 | 11 | | 2016 | 1 | 6 | 7 | | 2017 | 1 | 8 | 9 | | 2018 | 4 | 10 | 14 | | 2019 | 0 | 13 | 13 | | 2020 | 0 | 3 | 3 |
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Below are the most recent publications written about "Protein Isoforms" by people in Profiles.
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Guo H, Zhang Q, Dai R, Yu B, Hoekzema K, Tan J, Tan S, Jia X, Chung WK, Hernan R, Alkuraya FS, Alsulaiman A, Al-Muhaizea MA, Lesca G, Pons L, Labalme A, Laux L, Bryant E, Brown NJ, Savva E, Ayres S, Eratne D, Peeters H, Bilan F, Letienne-Cejudo L, Gilbert-Dussardier B, Ruiz-Arana IL, Merlini JM, Boizot A, Bartoloni L, Santoni F, Karlowicz D, McDonald M, Wu H, Hu Z, Chen G, Ou J, Brasch-Andersen C, Fagerberg CR, Dreyer I, Chun-Hui Tsai A, Slegesky V, McGee RB, Daniels B, Sellars EA, Carpenter LA, Schaefer B, Sacoto MJG, Begtrup A, Schnur RE, Punj S, Wentzensen IM, Rhodes L, Pan Q, Bernier RA, Chen C, Eichler EE, Xia K. NCKAP1 Disruptive Variants Lead to a Neurodevelopmental Disorder with Core Features of Autism. Am J Hum Genet. 2020 11 05; 107(5):963-976.
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Peters CH, Myers ME, Juchno J, Haimbaugh C, Bichraoui H, Du Y, Bankston JR, Walker LA, Proenza C. Isoform-specific regulation of HCN4 channels by a family of endoplasmic reticulum proteins. Proc Natl Acad Sci U S A. 2020 07 28; 117(30):18079-18090.
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Li S, Mecca A, Kim J, Caprara GA, Wagner EL, Du TT, Petrov L, Xu W, Cui R, Rebustini IT, Kachar B, Peng AW, Shin JB. Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex. Nat Commun. 2020 04 29; 11(1):2066.
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Timic Stamenic T, Feseha S, Valdez R, Zhao W, Klawitter J, Todorovic SM. Alterations in Oscillatory Behavior of Central Medial Thalamic Neurons Demonstrate a Key Role of CaV3.1 Isoform of T-Channels During Isoflurane-Induced Anesthesia. Cereb Cortex. 2019 12 17; 29(11):4679-4696.
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Lau E, Han Y, Williams DR, Thomas CT, Shrestha R, Wu JC, Lam MPY. Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome. Cell Rep. 2019 12 10; 29(11):3751-3765.e5.
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Dickow J, Francois S, Kaiserling RL, Malyshkina A, Drexler I, Westendorf AM, Lang KS, Santiago ML, Dittmer U, Sutter K. Diverse Immunomodulatory Effects of Individual IFNa Subtypes on Virus-Specific CD8+ T Cell Responses. Front Immunol. 2019; 10:2255.
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Johnson CA, Walklate J, Svicevic M, Mijailovich SM, Vera C, Karabina A, Leinwand LA, Geeves MA. The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles. J Biol Chem. 2019 09 27; 294(39):14267-14278.
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Weng L, Wang Q, Yu S, Yang X, Lynch DR, Mesaros C, Blair IA. Evaluation of antibodies for western blot analysis of frataxin protein isoforms. J Immunol Methods. 2019 11; 474:112629.
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Hemmati S, Sinclair T, Tong M, Bartholdy B, Okabe RO, Ames K, Ostrodka L, Haque T, Kaur I, Mills TS, Agarwal A, Pietras EM, Zhao JJ, Roberts TM, Gritsman K. PI3 kinase alpha and delta promote hematopoietic stem cell activation. JCI Insight. 2019 05 23; 5.
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Kohno S, Shiozaki Y, Keenan AL, Miyazaki-Anzai S, Miyazaki M. An N-terminal-truncated isoform of FAM134B (FAM134B-2) regulates starvation-induced hepatic selective ER-phagy. Life Sci Alliance. 2019 06; 2(3).
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