 Protein Isoforms
"Protein Isoforms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
| Descriptor ID |
D020033
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| MeSH Number(s) |
D12.776.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Isoforms".
Below are MeSH descriptors whose meaning is more specific than "Protein Isoforms".
This graph shows the total number of publications written about "Protein Isoforms" by people in this website by year, and whether "Protein Isoforms" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1999 | 1 | 5 | 6 | | 2000 | 2 | 11 | 13 | | 2001 | 1 | 14 | 15 | | 2002 | 2 | 10 | 12 | | 2003 | 2 | 12 | 14 | | 2004 | 0 | 12 | 12 | | 2005 | 2 | 16 | 18 | | 2006 | 1 | 14 | 15 | | 2007 | 0 | 5 | 5 | | 2008 | 1 | 14 | 15 | | 2009 | 0 | 11 | 11 | | 2010 | 1 | 8 | 9 | | 2011 | 2 | 8 | 10 | | 2012 | 0 | 17 | 17 | | 2013 | 1 | 7 | 8 | | 2014 | 0 | 7 | 7 | | 2015 | 1 | 13 | 14 | | 2016 | 1 | 7 | 8 | | 2017 | 1 | 7 | 8 | | 2018 | 4 | 7 | 11 | | 2019 | 0 | 12 | 12 | | 2020 | 2 | 3 | 5 | | 2021 | 1 | 5 | 6 | | 2022 | 0 | 5 | 5 | | 2023 | 0 | 9 | 9 | | 2024 | 4 | 5 | 9 |
To return to the timeline, click here.
Below are the most recent publications written about "Protein Isoforms" by people in Profiles.
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Pasquesi GIM, Allen H, Ivancevic A, Barbachano-Guerrero A, Joyner O, Guo K, Simpson DM, Gapin K, Horton I, Nguyen LL, Yang Q, Warren CJ, Florea LD, Bitler BG, Santiago ML, Sawyer SL, Chuong EB. Regulation of human interferon signaling by transposon exonization. Cell. 2024 Dec 26; 187(26):7621-7636.e19.
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Upadhyay V, Ray S, Panja S, Saviola AJ, Maluf NK, Mallela KMG. Biophysical characterization of the dystrophin C-terminal domain: Dystrophin interacts differentially with dystrobrevin isoforms. J Biol Chem. 2024 Dec; 300(12):108002.
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Ueda MT, Inamo J, Miya F, Shimada M, Yamaguchi K, Kochi Y. Functional and dynamic profiling of transcript isoforms reveals essential roles of alternative splicing in interferon response. Cell Genom. 2024 Oct 09; 4(10):100654.
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Dziulko AK, Allen H, Chuong EB. An endogenous retrovirus regulates tumor-specific expression of the immune transcriptional regulator SP140. Hum Mol Genet. 2024 08 06; 33(16):1454-1464.
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Inamo J, Suzuki A, Ueda MT, Yamaguchi K, Nishida H, Suzuki K, Kaneko Y, Takeuchi T, Hatano H, Ishigaki K, Ishihama Y, Yamamoto K, Kochi Y. Long-read sequencing for 29 immune cell subsets reveals disease-linked isoforms. Nat Commun. 2024 May 28; 15(1):4285.
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Haddad G, Blaine J. Identification of Four Mouse FcRn Splice Variants and FcRn-Specific Vesicles. Cells. 2024 03 29; 13(7).
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Pandi B, Brenman S, Black A, Ng DCM, Lau E, Lam MPY. Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart. J Proteome Res. 2024 Aug 02; 23(8):3161-3173.
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Lee FFY, Harris C, Alper S. RNA Binding Proteins that Mediate LPS-induced Alternative Splicing of the MyD88 Innate Immune Regulator. J Mol Biol. 2024 Apr 15; 436(8):168497.
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Morales AE, Gumenick R, Genovese CM, Jang YY, Ouedraogo A, Ib??ez de Garayo M, Pannellini T, Patel S, Bott ME, Alvarez J, Mun SS, Totonchy J, Gautam A, Delgado de la Mora J, Chang S, Wirth D, Horenstein M, Dao T, Scheinberg DA, Rubinstein PG, Semeere A, Martin J, Godfrey CC, Moser CB, Matining RM, Campbell TB, Borok MZ, Krown SE, Cesarman E. Wilms' tumor 1 (WT1) antigen is overexpressed in Kaposi Sarcoma and is regulated by KSHV vFLIP. PLoS Pathog. 2024 Jan; 20(1):e1011881.
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Innes PA, Goebl AM, Smith CCR, Rosenberger K, Kane NC. Gene expression and alternative splicing contribute to adaptive divergence of ecotypes. Heredity (Edinb). 2024 03; 132(3):120-132.
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