 Ryanodine Receptor Calcium Release Channel
"Ryanodine Receptor Calcium Release Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
| Descriptor ID |
D019837
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| MeSH Number(s) |
D12.776.157.530.400.150.800 D12.776.210.500.800 D12.776.543.550.450.150.800 D12.776.543.585.400.150.800
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| Concept/Terms |
Ryanodine Receptor Calcium Release Channel- Ryanodine Receptor Calcium Release Channel
- Receptor, Ryanodine
- Ca Release Channel-Ryanodine Receptor
- Ca Release Channel Ryanodine Receptor
- Calcium-Ryanodine Receptor Complex
- Calcium Ryanodine Receptor Complex
- Complex, Calcium-Ryanodine Receptor
- Receptor Complex, Calcium-Ryanodine
- Ryanodine Receptor
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Below are MeSH descriptors whose meaning is more general than "Ryanodine Receptor Calcium Release Channel".
Below are MeSH descriptors whose meaning is more specific than "Ryanodine Receptor Calcium Release Channel".
This graph shows the total number of publications written about "Ryanodine Receptor Calcium Release Channel" by people in this website by year, and whether "Ryanodine Receptor Calcium Release Channel" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 0 | 3 | 3 | | 1997 | 0 | 2 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 2 | 0 | 2 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2005 | 2 | 1 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 1 | 2 | | 2008 | 2 | 2 | 4 | | 2009 | 4 | 1 | 5 | | 2010 | 2 | 2 | 4 | | 2011 | 1 | 1 | 2 | | 2012 | 2 | 2 | 4 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 3 | 4 | | 2015 | 3 | 1 | 4 | | 2016 | 2 | 1 | 3 | | 2017 | 3 | 1 | 4 | | 2018 | 1 | 2 | 3 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ryanodine Receptor Calcium Release Channel" by people in Profiles.
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Lipsett DB, Frisk M, Aronsen JM, Nordén ES, Buonarati OR, Cataliotti A, Hell JW, Sjaastad I, Christensen G, Louch WE. Cardiomyocyte substructure reverts to an immature phenotype during heart failure. J Physiol. 2019 04; 597(7):1833-1853.
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Woulfe KC, Wilson CE, Nau S, Chau S, Phillips EK, Zang S, Tompkins C, Sucharov CC, Miyamoto SD, Stauffer BL. Acute isoproterenol leads to age-dependent arrhythmogenesis in guinea pigs. . 2018 10 01; 315(4):H1051-H1062.
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Roston TM, Yuchi Z, Kannankeril PJ, Hathaway J, Vinocur JM, Etheridge SP, Potts JE, Maginot KR, Salerno JC, Cohen MI, Hamilton RM, Pflaumer A, Mohammed S, Kimlicka L, Kanter RJ, LaPage MJ, Collins KK, Gebauer RA, Temple JD, Batra AS, Erickson C, Miszczak-Knecht M, Kubuš P, Bar-Cohen Y, Kantoch M, Thomas VC, Hessling G, Anderson C, Young ML, Choi SHJ, Cabrera Ortega M, Lau YR, Johnsrude CL, Fournier A, Van Petegem F, Sanatani S. The clinical and genetic spectrum of catecholaminergic polymorphic ventricular tachycardia: findings from an international multicentre registry. Europace. 2018 03 01; 20(3):541-547.
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Polster A, Nelson BR, Papadopoulos S, Olson EN, Beam KG. Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1. J Gen Physiol. 2018 04 02; 150(4):613-624.
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Polster A, Perni S, Filipova D, Moua O, Ohrtman JD, Bichraoui H, Beam KG, Papadopoulos S. Junctional trafficking and restoration of retrograde signaling by the cytoplasmic RyR1 domain. J Gen Physiol. 2018 02 05; 150(2):293-306.
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Klipp RC, Li N, Wang Q, Word TA, Sibrian-Vazquez M, Strongin RM, Wehrens XHT, Abramson JJ. EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2. Heart Rhythm. 2018 04; 15(4):578-586.
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Perni S, Lavorato M, Beam KG. De novo reconstitution reveals the proteins required for skeletal muscle voltage-induced Ca2+ release. Proc Natl Acad Sci U S A. 2017 12 26; 114(52):13822-13827.
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Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H. Mammalian ?2 AMPK regulates intrinsic heart rate. Nat Commun. 2017 11 02; 8(1):1258.
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Li L, Li J, Drum BM, Chen Y, Yin H, Guo X, Luckey SW, Gilbert ML, McKnight GS, Scott JD, Santana LF, Liu Q. Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve. Cardiovasc Res. 2017 02; 113(2):147-159.
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Li N, Wang Q, Sibrian-Vazquez M, Klipp RC, Reynolds JO, Word TA, Scott L, Salama G, Strongin RM, Abramson JJ, Wehrens XHT. Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs. Int J Cardiol. 2017 Jan 15; 227:668-673.
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