 Cytochrome P-450 CYP11B2
"Cytochrome P-450 CYP11B2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
| Descriptor ID |
D019405
|
| MeSH Number(s) |
D08.244.453.484.500 D08.244.453.915.050 D08.811.682.690.708.170.425.500 D08.811.682.690.708.170.915.050 D12.776.422.220.453.484.500 D12.776.422.220.453.915.050
|
| Concept/Terms |
Cytochrome P-450 CYP11B2- Cytochrome P-450 CYP11B2
- Cytochrome P 450 CYP11B2
- Aldosterone Synthase
- Aldosterone Synthase Cytochrome P-450
- Aldosynthase
- Cytochrome P450Aldo
- P450c11AS
- Cytochrome P450 11B2
- Cytochrome P-450c11AS
- Cytochrome P 450c11AS
- CYP11B2
- Steroid 18-Hydroxylase
- Steroid 18 Hydroxylase
- CYP 11B2
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP11B2".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP11B2".
This graph shows the total number of publications written about "Cytochrome P-450 CYP11B2" by people in this website by year, and whether "Cytochrome P-450 CYP11B2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Cytochrome P-450 CYP11B2" by people in Profiles.
-
Kumar R, Nejatizadeh A, Gupta M, Markan A, Tyagi S, Jain SK, Pasha MA. The epistasis between vascular homeostasis genes is apparent in essential hypertension. Atherosclerosis. 2012 Feb; 220(2):418-24.
-
Nejatizadeh A, Kumar R, Stobdan T, Goyal AK, Gupta M, Tyagi S, Jain SK, Pasha MA. CYP11B2 gene haplotypes independently and in concurrence with aldosterone and aldosterone to renin ratio increase the risk of hypertension. Clin Biochem. 2010 Jan; 43(1-2):136-41.
-
Tsybouleva N, Zhang L, Chen S, Patel R, Lutucuta S, Nemoto S, DeFreitas G, Entman M, Carabello BA, Roberts R, Marian AJ. Aldosterone, through novel signaling proteins, is a fundamental molecular bridge between the genetic defect and the cardiac phenotype of hypertrophic cardiomyopathy. Circulation. 2004 Mar 16; 109(10):1284-91.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|