Phosphotyrosine
"Phosphotyrosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
Descriptor ID |
D019000
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MeSH Number(s) |
D12.125.072.050.875.750 D12.125.740.740
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphotyrosine".
Below are MeSH descriptors whose meaning is more specific than "Phosphotyrosine".
This graph shows the total number of publications written about "Phosphotyrosine" by people in this website by year, and whether "Phosphotyrosine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 3 | 3 | 1995 | 0 | 1 | 1 | 1996 | 0 | 4 | 4 | 1997 | 0 | 3 | 3 | 1998 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2000 | 0 | 1 | 1 | 2001 | 0 | 4 | 4 | 2004 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2006 | 0 | 4 | 4 | 2008 | 1 | 2 | 3 | 2009 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphotyrosine" by people in Profiles.
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Weir ME, Mann JE, Corwin T, Fulton ZW, Hao JM, Maniscalco JF, Kenney MC, Roman Roque KM, Chapdelaine EF, Stelzl U, Deming PB, Ballif BA, Hinkle KL. Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacity. FEBS Lett. 2016 04; 590(8):1042-52.
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Neuber S, J?ger S, Meyer M, Wischmann V, Koch PJ, Moll R, Schmidt A. c-Src mediated tyrosine phosphorylation of plakophilin 3 as a new mechanism to control desmosome composition in cells exposed to oxidative stress. Cell Tissue Res. 2015 Mar; 359(3):799-816.
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Zhu Y, Yao S, Iliopoulou BP, Han X, Augustine MM, Xu H, Phennicie RT, Flies SJ, Broadwater M, Ruff W, Taube JM, Zheng L, Luo L, Zhu G, Chen J, Chen L. B7-H5 costimulates human T cells via CD28H. Nat Commun. 2013; 4:2043.
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Chafe SC, Pierce JB, Mangroo D. Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation. PLoS One. 2012; 7(8):e42501.
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Wang Q, Rajshankar D, Branch DR, Siminovitch KA, Herrera Abreu MT, Downey GP, McCulloch CA. Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling. J Biol Chem. 2009 Jul 31; 284(31):20763-72.
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Lyubchenko T, Nielsen JP, Miller SM, Liubchenko GA, Holers VM. Role of initial protein phosphorylation events and localized release-activated calcium influx in B cell antigen receptor signaling. J Leukoc Biol. 2009 Feb; 85(2):298-309.
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Jin L, Waterman PM, Jonscher KR, Short CM, Reisdorph NA, Cambier JC. MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals. Mol Cell Biol. 2008 Aug; 28(16):5014-26.
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Bijli KM, Fazal F, Minhajuddin M, Rahman A. Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65. J Biol Chem. 2008 May 23; 283(21):14674-84.
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Huang F, Goh LK, Sorkin A. EGF receptor ubiquitination is not necessary for its internalization. Proc Natl Acad Sci U S A. 2007 Oct 23; 104(43):16904-9.
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Bijli KM, Minhajuddin M, Fazal F, O'Reilly MA, Platanias LC, Rahman A. c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2007 Feb; 292(2):L396-404.
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