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Integrin alpha Chains

"Integrin alpha Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4.


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This graph shows the total number of publications written about "Integrin alpha Chains" by people in this website by year, and whether "Integrin alpha Chains" was a major or minor topic of these publications.
Bar chart showing 16 publications over 9 distinct years, with a maximum of 3 publications in 1998 and 2013
To see the data from this visualization as text, click here.

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