 Survival of Motor Neuron 1 Protein
"Survival of Motor Neuron 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An SMN complex protein that contains a TUDOR DOMAIN and is essential for the function of the SMN protein complex. In humans, the protein is encoded by a single gene found near the inversion TELOMERE of a large inverted region of CHROMOSOME 5. Mutations in the gene coding for survival of motor neuron 1 protein may result in SPINAL MUSCULAR ATROPHIES OF CHILDHOOD.
| Descriptor ID |
D055533
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| MeSH Number(s) |
D12.776.157.725.875.500 D12.776.580.922.500 D12.776.664.962.875.500
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| Concept/Terms |
Survival of Motor Neuron 1 Protein- Survival of Motor Neuron 1 Protein
- SMN Protein (Spinal Muscular Atrophy)
- Survival of Motor Neuron 1, Telomeric Protein
- Survival Motor Neuron Protein 1
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Below are MeSH descriptors whose meaning is more general than "Survival of Motor Neuron 1 Protein".
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This graph shows the total number of publications written about "Survival of Motor Neuron 1 Protein" by people in this website by year, and whether "Survival of Motor Neuron 1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Survival of Motor Neuron 1 Protein" by people in Profiles.
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Han KJ, Foster D, Harhaj EW, Dzieciatkowska M, Hansen K, Liu CW. Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity. Hum Mol Genet. 2016 Apr 01; 25(7):1392-405.
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Shukla S, Parker R. Quality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion. Proc Natl Acad Sci U S A. 2014 Aug 12; 111(32):E3277-86.
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Kang PB, Gooch CL, McDermott MP, Darras BT, Finkel RS, Yang ML, Sproule DM, Chung WK, Kaufmann P, de Vivo DC. The motor neuron response to SMN1 deficiency in spinal muscular atrophy. Muscle Nerve. 2014 May; 49(5):636-44.
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Han KJ, Foster DG, Zhang NY, Kanisha K, Dzieciatkowska M, Sclafani RA, Hansen KC, Peng J, Liu CW. Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron. J Biol Chem. 2012 Dec 21; 287(52):43741-52.
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