 Nucleosomes
"Nucleosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core. This core is composed of the histones H2A, H2B, H3, and H4.
| Descriptor ID |
D009707
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| MeSH Number(s) |
A11.284.430.106.279.345.190.160.180.625 D12.776.664.224.550 G05.360.160.180.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleosomes".
Below are MeSH descriptors whose meaning is more specific than "Nucleosomes".
This graph shows the total number of publications written about "Nucleosomes" by people in this website by year, and whether "Nucleosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1998 | 0 | 1 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 2 | 1 | 3 | | 2005 | 1 | 1 | 2 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 2 | 1 | 3 | | 2011 | 9 | 0 | 9 | | 2012 | 2 | 1 | 3 | | 2013 | 7 | 3 | 10 | | 2014 | 5 | 5 | 10 | | 2015 | 3 | 1 | 4 | | 2016 | 2 | 5 | 7 | | 2017 | 8 | 4 | 12 | | 2018 | 5 | 4 | 9 | | 2019 | 3 | 2 | 5 | | 2020 | 0 | 3 | 3 |
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Below are the most recent publications written about "Nucleosomes" by people in Profiles.
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Gaullier G, Roberts G, Muthurajan UM, Bowerman S, Rudolph J, Mahadevan J, Jha A, Rae PS, Luger K. Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1. PLoS One. 2020; 15(11):e0240932.
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Tencer AH, Cox KL, Wright GM, Zhang Y, Petell CJ, Klein BJ, Strahl BD, Black JC, Poirier MG, Kutateladze TG. Molecular mechanism of the MORC4 ATPase activation. Nat Commun. 2020 10 29; 11(1):5466.
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Liu H, Ramachandran S, Fong N, Phang T, Lee S, Parsa P, Liu X, Harmacek L, Danhorn T, Song T, Oh S, Zhang Q, Chen Z, Zhang Q, Tu TH, Happoldt C, O'Conner B, Janknecht R, Li CY, Marrack P, Kappler J, Leach S, Zhang G. JMJD5 couples with CDK9 to release the paused RNA polymerase II. Proc Natl Acad Sci U S A. 2020 08 18; 117(33):19888-19895.
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Makowski MM, Gaullier G, Luger K. Picking a nucleosome lock: Sequence- and structure-specific recognition of the nucleosome. J Biosci. 2020; 45.
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Zhang Y, Kutateladze TG. Liquid-liquid phase separation is an intrinsic physicochemical property of chromatin. Nat Struct Mol Biol. 2019 12; 26(12):1085-1086.
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Zhang Y, Kutateladze TG. Methylation of Histone H3K79 by Dot1L Requires Multiple Contacts with the Ubiquitinated Nucleosome. Mol Cell. 2019 06 06; 74(5):862-863.
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Connelly KE, Weaver TM, Alpsoy A, Gu BX, Musselman CA, Dykhuizen EC. Engagement of DNA and H3K27me3 by the CBX8 chromodomain drives chromatin association. Nucleic Acids Res. 2019 03 18; 47(5):2289-2305.
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Musselman CA, Kutateladze TG. Strategies for Generating Modified Nucleosomes: Applications within Structural Biology Studies. ACS Chem Biol. 2019 04 19; 14(4):579-586.
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McCauley MJ, Huo R, Becker N, Holte MN, Muthurajan UM, Rouzina I, Luger K, Maher LJ, Israeloff NE, Williams MC. Single and double box HMGB proteins differentially destabilize nucleosomes. Nucleic Acids Res. 2019 01 25; 47(2):666-678.
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Klocko AD, Uesaka M, Ormsby T, Rountree MR, Wiles ET, Adhvaryu KK, Honda S, Selker EU. Nucleosome Positioning by an Evolutionarily Conserved Chromatin Remodeler Prevents Aberrant DNA Methylation in Neurospora. Genetics. 2019 02; 211(2):563-578.
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