Nucleosomes
"Nucleosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The repeating structural units of chromatin, each consisting of approximately 200 base pairs of DNA wound around a protein core. This core is composed of the histones H2A, H2B, H3, and H4.
Descriptor ID |
D009707
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MeSH Number(s) |
A11.284.430.106.279.345.190.160.180.625 D12.776.664.224.550 G05.360.160.180.625
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nucleosomes".
Below are MeSH descriptors whose meaning is more specific than "Nucleosomes".
This graph shows the total number of publications written about "Nucleosomes" by people in this website by year, and whether "Nucleosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 | 1997 | 1 | 0 | 1 | 1998 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2004 | 2 | 1 | 3 | 2005 | 1 | 1 | 2 | 2010 | 1 | 1 | 2 | 2011 | 8 | 0 | 8 | 2012 | 1 | 1 | 2 | 2013 | 5 | 2 | 7 | 2014 | 5 | 4 | 9 | 2015 | 2 | 1 | 3 | 2016 | 2 | 2 | 4 | 2017 | 6 | 4 | 10 | 2018 | 4 | 2 | 6 | 2019 | 2 | 2 | 4 | 2020 | 0 | 2 | 2 | 2021 | 6 | 3 | 9 | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nucleosomes" by people in Profiles.
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Musselman CA, Kutateladze TG. Visualizing Conformational Ensembles of the Nucleosome by NMR. ACS Chem Biol. 2022 03 18; 17(3):495-502.
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Rudolph J, Muthurajan UM, Palacio M, Mahadevan J, Roberts G, Erbse AH, Dyer PN, Luger K. The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol Cell. 2021 12 16; 81(24):4994-5006.e5.
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Voong CK, Goodrich JA, Kugel JF. Interactions of HMGB Proteins with the Genome and the Impact on Disease. Biomolecules. 2021 10 02; 11(10).
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Liu Y, Bisio H, Toner CM, Jeudy S, Philippe N, Zhou K, Bowerman S, White A, Edwards G, Abergel C, Luger K. Virus-encoded histone doublets are essential and form nucleosome-like structures. Cell. 2021 08 05; 184(16):4237-4250.e19.
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Klein BJ, Deshpande A, Cox KL, Xuan F, Zandian M, Barbosa K, Khanal S, Tong Q, Zhang Y, Zhang P, Sinha A, Bohlander SK, Shi X, Wen H, Poirier MG, Deshpande AJ, Kutateladze TG. The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations. Nat Commun. 2021 07 05; 12(1):4130.
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Mauney AW, Muthurajan UM, Luger K, Pollack L. Solution structure(s) of trinucleosomes from contrast variation SAXS. Nucleic Acids Res. 2021 05 21; 49(9):5028-5037.
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Vann KR, Klein BJ, Kutateladze TG. Mechanistic similarities in recognition of histone tails and DNA by epigenetic readers. Curr Opin Struct Biol. 2021 12; 71:1-6.
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Morrison EA, Baweja L, Poirier MG, Wereszczynski J, Musselman CA. Nucleosome composition regulates the histone H3 tail conformational ensemble and accessibility. Nucleic Acids Res. 2021 05 07; 49(8):4750-4767.
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Rabdano SO, Shannon MD, Izmailov SA, Gonzalez Salguero N, Zandian M, Purusottam RN, Poirier MG, Skrynnikov NR, Jaroniec CP. Histone H4 Tails in Nucleosomes: a Fuzzy Interaction with DNA. Angew Chem Int Ed Engl. 2021 03 15; 60(12):6480-6487.
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Ghoneim M, Fuchs HA, Musselman CA. Histone Tail Conformations: A Fuzzy Affair with DNA. Trends Biochem Sci. 2021 07; 46(7):564-578.
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