 Lectins
"Lectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.
| Descriptor ID |
D037102
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| MeSH Number(s) |
D12.776.503
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lectins".
Below are MeSH descriptors whose meaning is more specific than "Lectins".
This graph shows the total number of publications written about "Lectins" by people in this website by year, and whether "Lectins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1994 | 2 | 0 | 2 | | 1995 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 0 | 1 | 1 | | 2010 | 1 | 2 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2016 | 2 | 0 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Lectins" by people in Profiles.
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Uchil PD, Pi R, Haugh KA, Ladinsky MS, Ventura JD, Barrett BS, Santiago ML, Bjorkman PJ, Kassiotis G, Sewald X, Mothes W. A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus. Cell Host Microbe. 2019 01 09; 25(1):87-100.e10.
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Rodriguez J, O'Neill S, Walczak MA. Constrained saccharides: a review of structure, biology, and synthesis. Nat Prod Rep. 2018 03 01; 35(3):220-229.
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Banda NK, Acharya S, Scheinman RI, Mehta G, Takahashi M, Endo Y, Zhou W, Farrar CA, Sacks SH, Fujita T, Sekine H, Holers VM. Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2. J Immunol. 2017 09 01; 199(5):1835-1845.
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Vu A, Kosmiski LA, Beitelshees AL, Prigeon R, Sidhom MS, Bredbeck B, Predhomme J, Deininger KM, Aquilante CL. Pharmacodynamic Effects of Low-Dose Pioglitazone in Patients with the Metabolic Syndrome without Diabetes Mellitus. Pharmacotherapy. 2016 Mar; 36(3):252-62.
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Wesolowska-Andersen A, Seibold MA. Is the Road to Precision Medicine in Chronic Lung Disease Paved with Degraded Chitin? Am J Respir Crit Care Med. 2016 Jan 15; 193(2):107-8.
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Scruggs AK, Cioffi EA, Cioffi DL, King JA, Bauer NN. Lectin-Based Characterization of Vascular Cell Microparticle Glycocalyx. PLoS One. 2015; 10(8):e0135533.
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Santos CB, Davidson J, Covar RA, Spahn JD. The chitinase-like protein YKL-40 is not a useful biomarker for severe persistent asthma in children. Ann Allergy Asthma Immunol. 2014 Sep; 113(3):263-6.
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Luo W, Mayeux J, Gutierrez T, Russell L, Getahun A, Müller J, Tedder T, Parnes J, Rickert R, Nitschke L, Cambier J, Satterthwaite AB, Garrett-Sinha LA. A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. J Immunol. 2014 Jul 15; 193(2):909-920.
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Silva J, Polesskaya O, Knight W, Zheng JT, Granger M, Lopez T, Ontiveros F, Feng C, Yan C, Kasischke KA, Dewhurst S. Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5. J Neuroinflammation. 2012 Nov 20; 9:253.
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Rumer KK, Post MD, Larivee RS, Zink M, Uyenishi J, Kramer A, Teoh D, Bogart K, Winn VD. Siglec-6 is expressed in gestational trophoblastic disease and affects proliferation, apoptosis and invasion. Endocr Relat Cancer. 2012 Dec; 19(6):827-40.
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