Nuclear Receptor Coactivator 1
"Nuclear Receptor Coactivator 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and THYROID HORMONE RECEPTORS. It contains a HISTONE ACETYLTRANSFRASE activity that may play a role in the transcriptional activation of CHROMATIN regions.
Descriptor ID |
D056920
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MeSH Number(s) |
D08.811.913.050.134.415.500.100 D12.644.360.024.314.100 D12.776.157.057.080.100 D12.776.260.103.782 D12.776.476.024.394.100 D12.776.660.675.100 D12.776.930.125.500.625 D12.776.930.617.100
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Coactivator 1".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Coactivator 1".
This graph shows the total number of publications written about "Nuclear Receptor Coactivator 1" by people in this website by year, and whether "Nuclear Receptor Coactivator 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Coactivator 1" by people in Profiles.
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Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K, Hinton A, Yan X, Keogh JM, Henning E, Banton MC, Hendricks AE, Bochukova EG, Mistry V, Lawler KL, Liao L, Xu J, O'Rahilly S, Tong Q, O'Malley BW, Farooqi IS, Xu Y. Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. Nat Commun. 2019 04 12; 10(1):1718.
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Arnold MA, Barr FG. Molecular diagnostics in the management of rhabdomyosarcoma. Expert Rev Mol Diagn. 2017 02; 17(2):189-194.
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Abdel-Hafiz HA, Horwitz KB. Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation. BMC Mol Biol. 2012 Mar 22; 13:10.
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Abdel-Hafiz H, Dudevoir ML, Horwitz KB. Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation. J Biol Chem. 2009 Apr 03; 284(14):9099-108.
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Tung L, Abdel-Hafiz H, Shen T, Harvell DM, Nitao LK, Richer JK, Sartorius CA, Takimoto GS, Horwitz KB. Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B. Mol Endocrinol. 2006 Nov; 20(11):2656-70.
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Graham JD, Bain DL, Richer JK, Jackson TA, Tung L, Horwitz KB. Thoughts on tamoxifen resistant breast cancer. Are coregulators the answer or just a red herring? J Steroid Biochem Mol Biol. 2000 Nov 30; 74(5):255-9.
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