 Germinal Center
"Germinal Center" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.
| Descriptor ID |
D018858
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| MeSH Number(s) |
A10.549.400.500 A15.382.520.604.412.500
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| Concept/Terms |
Germinal Center- Germinal Center
- Center, Germinal
- Centers, Germinal
- Germinal Centers
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Below are MeSH descriptors whose meaning is more general than "Germinal Center".
Below are MeSH descriptors whose meaning is more specific than "Germinal Center".
This graph shows the total number of publications written about "Germinal Center" by people in this website by year, and whether "Germinal Center" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2002 | 1 | 2 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 3 | 4 | | 2006 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 0 | 2 | | 2014 | 2 | 2 | 4 | | 2015 | 2 | 4 | 6 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 2 | 3 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Germinal Center" by people in Profiles.
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Klarquist J, Cantrell R, Lehn MA, Lampe K, Hennies CM, Hoebe K, Janssen EM. Type I IFN Drives Experimental Systemic Lupus Erythematosus by Distinct Mechanisms in CD4 T Cells and B Cells. Immunohorizons. 2020 03 11; 4(3):140-152.
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Beck SE, Veenhuis RT, Blankson JN. Does B Cell Follicle Exclusion of CD8+ T Cells Make Lymph Nodes Sanctuaries of HIV Replication? Front Immunol. 2019; 10:2362.
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Ryota H, Ishida M, Satoi S, Yanagimoto H, Yamamoto T, Kosaka H, Hirooka S, Yamaki S, Kotsuka M, Matsui Y, Ikeura T, Uchida K, Takaoka M, Okazaki K, Tsuta K. Clinicopathological and immunological features of follicular pancreatitis - a distinct disease entity characterised by Th17 activation. Histopathology. 2019 Apr; 74(5):709-717.
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Crouch MJ, Kosaraju R, Guesdon W, Armstrong M, Reisdorph N, Jain R, Fenton J, Shaikh SR. Frontline Science: A reduction in DHA-derived mediators in male obesity contributes toward defects in select B cell subsets and circulating antibody. J Leukoc Biol. 2019 08; 106(2):241-257.
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Farnsworth CW, Schott EM, Benvie A, Kates SL, Schwarz EM, Gill SR, Zuscik MJ, Mooney RA. Exacerbated Staphylococcus aureus Foot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity. J Immunol. 2018 07 15; 201(2):560-572.
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Dell'Aringa M, Reinhardt RL, Friedman RS, Jacobelli J. Live Imaging of IL-4-Expressing T Follicular Helper Cells in Explanted Lymph Nodes. Methods Mol Biol. 2018; 1799:225-235.
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Bove KE, Sheridan R, Fei L, Anders R, Chung CT, Cummings OW, Finegold MJ, Finn L, Ranganathan S, Kim G, Lovell M, Magid MS, Melin-Aldana H, Russo P, Shehata B, Wang L, White F, Chen Z, Spino C, Magee JC. Hepatic Hilar Lymph Node Reactivity at Kasai Portoenterostomy for Biliary Atresia: Correlations With Age, Outcome, and Histology of Proximal Biliary Remnant. Pediatr Dev Pathol. 2018 Jan-Feb; 21(1):29-40.
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Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest. 2017 Apr 03; 127(4):1392-1404.
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Li S, Folkvord JM, Rakasz EG, Abdelaal HM, Wagstaff RK, Kovacs KJ, Kim HO, Sawahata R, MaWhinney S, Masopust D, Connick E, Skinner PJ. Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo. J Virol. 2016 Dec 15; 90(24):11168-11180.
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Kohler SL, Pham MN, Folkvord JM, Arends T, Miller SM, Miles B, Meditz AL, McCarter M, Levy DN, Connick E. Germinal Center T Follicular Helper Cells Are Highly Permissive to HIV-1 and Alter Their Phenotype during Virus Replication. J Immunol. 2016 Mar 15; 196(6):2711-22.
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