 Germinal Center
"Germinal Center" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-LYMPHOCYTES are stimulated by antigens and helper T cells (T-LYMPHOCYTES, HELPER-INDUCER) are stimulated to generate memory cells.
| Descriptor ID |
D018858
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| MeSH Number(s) |
A10.549.400.500 A15.382.520.604.412.500
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| Concept/Terms |
Germinal Center- Germinal Center
- Center, Germinal
- Centers, Germinal
- Germinal Centers
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Below are MeSH descriptors whose meaning is more general than "Germinal Center".
Below are MeSH descriptors whose meaning is more specific than "Germinal Center".
This graph shows the total number of publications written about "Germinal Center" by people in this website by year, and whether "Germinal Center" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 2 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 3 | 3 | | 2006 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 0 | 2 | | 2014 | 2 | 2 | 4 | | 2015 | 1 | 3 | 4 | | 2016 | 2 | 1 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Germinal Center" by people in Profiles.
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Dell'Aringa M, Reinhardt RL, Friedman RS, Jacobelli J. Live Imaging of IL-4-Expressing T Follicular Helper Cells in Explanted Lymph Nodes. Methods Mol Biol. 2018; 1799:225-235.
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Bove KE, Sheridan R, Fei L, Anders R, Chung CT, Cummings OW, Finegold MJ, Finn L, Ranganathan S, Kim G, Lovell M, Magid MS, Melin-Aldana H, Russo P, Shehata B, Wang L, White F, Chen Z, Spino C, Magee JC. Hepatic Hilar Lymph Node Reactivity at Kasai Portoenterostomy for Biliary Atresia: Correlations With Age, Outcome, and Histology of Proximal Biliary Remnant. Pediatr Dev Pathol. 2018 Jan-Feb; 21(1):29-40.
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Rubtsova K, Rubtsov AV, Thurman JM, Mennona JM, Kappler JW, Marrack P. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest. 2017 Apr 03; 127(4):1392-1404.
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Li S, Folkvord JM, Rakasz EG, Abdelaal HM, Wagstaff RK, Kovacs KJ, Kim HO, Sawahata R, MaWhinney S, Masopust D, Connick E, Skinner PJ. Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo. J Virol. 2016 Dec 15; 90(24):11168-11180.
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Kohler SL, Pham MN, Folkvord JM, Arends T, Miller SM, Miles B, Meditz AL, McCarter M, Levy DN, Connick E. Germinal Center T Follicular Helper Cells Are Highly Permissive to HIV-1 and Alter Their Phenotype during Virus Replication. J Immunol. 2016 Mar 15; 196(6):2711-22.
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Chen Z, Elos MT, Viboolsittiseri SS, Gowan K, Leach SM, Rice M, Eder MD, Jones K, Wang JH. Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity. J Hematol Oncol. 2016 Jan 07; 9:2.
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Huang Y, Getahun A, Heiser RA, Detanico TO, Aviszus K, Kirchenbaum GA, Casper TL, Huang C, Aydintug MK, Carding SR, Ikuta K, Huang H, Wysocki LJ, Cambier JC, O'Brien RL, Born WK. ?d T Cells Shape Preimmune Peripheral B Cell Populations. J Immunol. 2016 Jan 01; 196(1):217-31.
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Klarquist J, Janssen EM. The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice. J Vis Exp. 2015 11 01; (105):e53319.
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Wu T, Shin HM, Moseman EA, Ji Y, Huang B, Harly C, Sen JM, Berg LJ, Gattinoni L, McGavern DB, Schwartzberg PL. TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. Cell Rep. 2015 Sep 29; 12(12):2099-110.
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Karnik T, Ozawa MG, Lefterova M, Luna-Fineman S, Alvarez E, Link M, Zehnder JL, Arber DA, Ohgami RS. The utility of IgM, CD21, HGAL and LMO2 in the diagnosis of pediatric follicular lymphoma. Hum Pathol. 2015 Apr; 46(4):629-33.
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