 Acetylcysteine
"Acetylcysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.
| Descriptor ID |
D000111
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| MeSH Number(s) |
D02.886.030.230.259 D12.125.166.230.259
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| Concept/Terms |
Acetylcysteine- Acetylcysteine
- N-Acetyl-L-cysteine
- N Acetyl L cysteine
- N-Acetylcysteine
- N Acetylcysteine
- Mercapturic Acid
- Acid, Mercapturic
Acetylcysteine Sodium- Acetylcysteine Sodium
- Sodium, Acetylcysteine
- Acetylcysteine, Monosodium Salt
- Monosodium Salt Acetylcysteine
Fluprowit- Fluprowit
- Optipect Hustengetränk
- Hustengetränk, Optipect
- Muco Sanigen
- Sanigen, Muco
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Below are MeSH descriptors whose meaning is more general than "Acetylcysteine".
Below are MeSH descriptors whose meaning is more specific than "Acetylcysteine".
This graph shows the total number of publications written about "Acetylcysteine" by people in this website by year, and whether "Acetylcysteine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 1 | 0 | 1 | | 2004 | 2 | 2 | 4 | | 2005 | 2 | 4 | 6 | | 2006 | 3 | 2 | 5 | | 2007 | 5 | 3 | 8 | | 2008 | 2 | 2 | 4 | | 2009 | 2 | 0 | 2 | | 2010 | 5 | 7 | 12 | | 2011 | 4 | 2 | 6 | | 2012 | 2 | 5 | 7 | | 2013 | 4 | 1 | 5 | | 2014 | 4 | 1 | 5 | | 2015 | 1 | 1 | 2 | | 2016 | 4 | 1 | 5 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 2 | 1 | 3 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Acetylcysteine" by people in Profiles.
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Keach JW, Stanislawski MA, Barón AE, Plomondon ME, Langner P, Amin A, Gilmartin HM, Waldo S, Maddox TM. Variation in contrast-associated acute kidney injury prophylaxis for percutaneous coronary intervention: insights from the Veterans Affairs Clinical Assessment, Reporting, and Tracking (CART) program. BMC Nephrol. 2020 04 28; 21(1):150.
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Wong A, Heard K, Graudins A, Dart R, Sivilotti MLA. Adducts Post Acetaminophen Overdose Treated with a 12-Hour vs 20-Hour Acetylcysteine Infusion. J Med Toxicol. 2020 04; 16(2):188-194.
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Moro F, Giannotti G, Caffino L, Marzo CM, Di Clemente A, Fumagalli F, Cervo L. Lasting reduction of nicotine-seeking behavior by chronic N-acetylcysteine during experimental cue-exposure therapy. Addict Biol. 2020 07; 25(4):e12771.
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Miller DR, Ingersoll MA, Chatterjee A, Baker B, Shrishrimal S, Kosmacek EA, Zhu Y, Cheng PW, Oberley-Deegan RE, Lin MF. p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance. Free Radic Biol Med. 2019 08 01; 139:24-34.
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Hoyte C, Dart RC. Transition to two-bag intravenous acetylcysteine for acetaminophen overdose: a poison center's experience. Clin Toxicol (Phila). 2019 03; 57(3):217-218.
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Mutsaers A, Green JP, Sivilotti MLA, Yarema MC, Tucker D, Johnson DW, Spyker DA, Rumack BH. Changing nomogram risk zone classification with serial testing after acute acetaminophen overdose: a retrospective database analysis. Clin Toxicol (Phila). 2019 06; 57(6):380-386.
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Bagati A, Moparthy S, Fink EE, Bianchi-Smiraglia A, Yun DH, Kolesnikova M, Udartseva OO, Wolff DW, Roll MV, Lipchick BC, Han Z, Kozlova NI, Jowdy P, Berman AE, Box NF, Rodriguez C, Bshara W, Kandel ES, Soengas MS, Paragh G, Nikiforov MA. KLF9-dependent ROS regulate melanoma progression in stage-specific manner. Oncogene. 2019 05; 38(19):3585-3597.
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Yarema M, Chopra P, Sivilotti MLA, Johnson D, Nettel-Aguirre A, Bailey B, Victorino C, Gosselin S, Purssell R, Thompson M, Spyker D, Rumack B. Anaphylactoid Reactions to Intravenous N-Acetylcysteine during Treatment for Acetaminophen Poisoning. J Med Toxicol. 2018 Jun; 14(2):120-127.
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Sharma S, Gralla J, Ordonez JG, Hurtado ME, Swenson ER, Schoene RB, Kelly JP, Callacondo D, Rivard C, Roncal-Jimenez C, Sirota J, Fuquay R, Jackson BP, Swenson KE, Johnson RJ, Hurtado A, Escudero E. Acetazolamide and N-acetylcysteine in the treatment of chronic mountain sickness (Monge's disease). Respir Physiol Neurobiol. 2017 12; 246:1-8.
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Yarema MC, Sivilotti MLA, Nettel-Aguirre A, Rumack BH. Reply to: Limitations of the evidence supporting use of undetectable acetaminophen levels obtained <4?hours post-ingestion to rule out toxicity. Clin Toxicol (Phila). 2017 06; 55(5):367.
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