 Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
"Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors that bind and internalize the granulocyte-macrophage stimulating factor. Their MW is believed to be 84 kD. The most mature myelomonocytic cells, specifically human neutrophils, macrophages, and eosinophils, express the highest number of affinity receptors for this growth factor.
| Descriptor ID |
D016187
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| MeSH Number(s) |
D12.776.543.750.705.852.150.310 D12.776.543.750.750.400.200.420
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| Concept/Terms |
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
- Receptors, Granulocyte Macrophage Colony Stimulating Factor
- Receptors, GM-CSF
- Receptors, GM CSF
- GM-CSF Receptors
- GM CSF Receptors
- CD116 Antigens
- CD116 Antigen
- Antigen, CD116
- Antigens, CD116
- GM-CSF Receptor
- GM CSF Receptor
- Receptor, GM-CSF
- Receptor, Granulocyte-Macrophage Colony-Stimulating Factor
- Receptor, Granulocyte Macrophage Colony Stimulating Factor
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Below are MeSH descriptors whose meaning is more general than "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor [D12.776.543.750.705.852.150.310]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor [D12.776.543.750.750.400.200.420]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 2 | 2 | | 2023 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptors, Granulocyte-Macrophage Colony-Stimulating Factor" by people in Profiles.
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Johnson NR, Yuan P, Castillo E, Lopez TP, Yue W, Bond A, Rivera BM, Sullivan MC, Hirouchi M, Giles K, Aoyagi A, Condello C. CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model. Nat Commun. 2023 01 09; 14(1):118.
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Erkes DA, Rosenbaum SR, Field CO, Chervoneva I, Villanueva J, Aplin AE. PLX3397 inhibits the accumulation of intra-tumoral macrophages and improves bromodomain and extra-terminal inhibitor efficacy in melanoma. Pigment Cell Melanoma Res. 2020 03; 33(2):372-377.
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Liu Y, Given KS, Dickson EL, Owens GP, Macklin WB, Bennett JL. Concentration-dependent effects of CSF1R inhibitors on oligodendrocyte progenitor cells ex vivo and in vivo. Exp Neurol. 2019 08; 318:32-41.
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Seitz S, Clarke P, Tyler KL. Pharmacologic Depletion of Microglia Increases Viral Load in the Brain and Enhances Mortality in Murine Models of Flavivirus-Induced Encephalitis. J Virol. 2018 08 15; 92(16).
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Kurtz SE, Eide CA, Kaempf A, Khanna V, Savage SL, Rofelty A, English I, Ho H, Pandya R, Bolosky WJ, Poon H, Deininger MW, Collins R, Swords RT, Watts J, Pollyea DA, Medeiros BC, Traer E, Tognon CE, Mori M, Druker BJ, Tyner JW. Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies. Proc Natl Acad Sci U S A. 2017 09 05; 114(36):E7554-E7563.
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Goldstein JI, Kominsky DJ, Jacobson N, Bowers B, Regalia K, Austin GL, Yousefi M, Falta MT, Fontenot AP, Gerich ME, Golden-Mason L, Colgan SP. Defective leukocyte GM-CSF receptor (CD116) expression and function in inflammatory bowel disease. Gastroenterology. 2011 Jul; 141(1):208-16.
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Suzuki T, Sakagami T, Rubin BK, Nogee LM, Wood RE, Zimmerman SL, Smolarek T, Dishop MK, Wert SE, Whitsett JA, Grabowski G, Carey BC, Stevens C, van der Loo JC, Trapnell BC. Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA. J Exp Med. 2008 Nov 24; 205(12):2703-10.
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Martinez-Moczygemba M, Doan ML, Elidemir O, Fan LL, Cheung SW, Lei JT, Moore JP, Tavana G, Lewis LR, Zhu Y, Muzny DM, Gibbs RA, Huston DP. Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1. J Exp Med. 2008 Nov 24; 205(12):2711-6.
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Waldschmidt TJ, Cook RT, Kovacs EJ. Alcohol and inflammation and immune responses: summary of the 2006 Alcohol and Immunology Research Interest Group (AIRIG) meeting. Alcohol. 2008 Mar; 42(2):137-42.
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Horita H, Frankel AE, Thorburn A. Acute-myeloid-leukemia-targeted toxins kill tumor cells by cell-type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death. Leukemia. 2008 Mar; 22(3):652-5.
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