 Dual Specificity Phosphatase 1
"Dual Specificity Phosphatase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.
| Descriptor ID |
D054638
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| MeSH Number(s) |
D08.811.277.352.650.587.200 D08.811.277.352.650.625.225.200 D08.811.277.352.650.775.250.200 D08.811.641.755.200 D12.644.360.268.200 D12.644.360.445.100 D12.776.476.268.200 D12.776.476.445.200
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| Concept/Terms |
Dual Specificity Phosphatase 1- Dual Specificity Phosphatase 1
- CL100 Phosphatase
- Phosphatase, CL100
- Externally Regulated Phosphatase (ERP)
- MKP-1 Phosphatase
- MKP 1 Phosphatase
- Phosphatase, MKP-1
- MAP Phosphatase-1
- MAP Phosphatase 1
- Phosphatase-1, MAP
- MAPK Phosphatase
- Phosphatase, MAPK
- Mitogen-Activated Protein Phosphatase-1
- Mitogen Activated Protein Phosphatase 1
- Phosphatase-1, Mitogen-Activated Protein
- Protein Phosphatase-1, Mitogen-Activated
- 3CH134 Phosphatase
- Phosphatase, 3CH134
- Map Kinase Phosphatase 1
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Below are MeSH descriptors whose meaning is more general than "Dual Specificity Phosphatase 1".
Below are MeSH descriptors whose meaning is more specific than "Dual Specificity Phosphatase 1".
This graph shows the total number of publications written about "Dual Specificity Phosphatase 1" by people in this website by year, and whether "Dual Specificity Phosphatase 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2008 | 1 | 0 | 1 | | 2010 | 2 | 1 | 3 | | 2012 | 2 | 2 | 4 | | 2013 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dual Specificity Phosphatase 1" by people in Profiles.
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Cartwright IM, Dowdell AS, Lanis JM, Brink KR, Mu A, Kostelecky RE, Schaefer REM, Welch N, Onyiah JC, Hall CHT, Gerich ME, Tabor JJ, Colgan SP. Mucosal acidosis elicits a unique molecular signature in epithelia and intestinal tissue mediated by GPR31-induced CREB phosphorylation. Proc Natl Acad Sci U S A. 2021 05 18; 118(20).
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Ruebel ML, Cotter M, Sims CR, Moutos DM, Badger TM, Cleves MA, Shankar K, Andres A. Obesity Modulates Inflammation and Lipid Metabolism Oocyte Gene Expression: A Single-Cell Transcriptome Perspective. J Clin Endocrinol Metab. 2017 06 01; 102(6):2029-2038.
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Buck AH, Coakley G, Simbari F, McSorley HJ, Quintana JF, Le Bihan T, Kumar S, Abreu-Goodger C, Lear M, Harcus Y, Ceroni A, Babayan SA, Blaxter M, Ivens A, Maizels RM. Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity. Nat Commun. 2014 Nov 25; 5:5488.
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Osterlund CD, Thompson V, Hinds L, Spencer RL. Absence of glucocorticoids augments stress-induced Mkp1 mRNA expression within the hypothalamic-pituitary-adrenal axis. J Endocrinol. 2014 Jan; 220(1):1-11.
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Fernandez-Boyanapalli R, Goleva E, Kolakowski C, Min E, Day B, Leung DY, Riches DW, Bratton DL, Sutherland ER. Obesity impairs apoptotic cell clearance in asthma. J Allergy Clin Immunol. 2013 Apr; 131(4):1041-7, 1047.e1-3.
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Park MS, He Q, Edwards MG, Sergew A, Riches DW, Albert RK, Douglas IS. Mitogen-activated protein kinase phosphatase-1 modulates regional effects of injurious mechanical ventilation in rodent lungs. Am J Respir Crit Care Med. 2012 Jul 01; 186(1):72-81.
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Zhang Y, Leung DY, Richers BN, Liu Y, Remigio LK, Riches DW, Goleva E. Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol. 2012 Mar 01; 188(5):2127-35.
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Goleva E, Jackson LP, Gleason M, Leung DY. Usefulness of PBMCs to predict clinical response to corticosteroids in asthmatic patients. J Allergy Clin Immunol. 2012 Mar; 129(3):687-693.e1.
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Jin Y, Hu D, Peterson EL, Eng C, Levin AM, Wells K, Beckman K, Kumar R, Seibold MA, Karungi G, Zoratti A, Gaggin J, Campbell J, Galanter J, Chapela R, Rodr?guez-Santana JR, Watson HG, Meade K, Lenoir M, Rodr?guez-Cintr?n W, Avila PC, Lanfear DE, Burchard EG, Williams LK. Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients. J Allergy Clin Immunol. 2010 Sep; 126(3):618-25.e1-2.
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Searing DA, Zhang Y, Murphy JR, Hauk PJ, Goleva E, Leung DY. Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use. J Allergy Clin Immunol. 2010 May; 125(5):995-1000.
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