 Excipients
"Excipients" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
| Descriptor ID |
D005079
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| MeSH Number(s) |
D26.650.700.419 D27.720.744.770.419
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Excipients".
Below are MeSH descriptors whose meaning is more specific than "Excipients".
This graph shows the total number of publications written about "Excipients" by people in this website by year, and whether "Excipients" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 2 | 1 | 3 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 4 | 5 | | 2002 | 0 | 1 | 1 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 2 | 2 | 4 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 3 | 4 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 2 | 3 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 3 | 0 | 3 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Excipients" by people in Profiles.
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Vanbillemont B, Carpenter JF, Probst C, De Beer T. The Impact of Formulation Composition and Process Settings of Traditional Batch Versus Continuous Freeze-Drying On Protein Aggregation. J Pharm Sci. 2020 11; 109(11):3308-3318.
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Movafaghi S, Wu H, Francino Urdániz IM, Bull DS, Kelly MD, Randolph TW, Goodwin AP. The Effect of Container Surface Passivation on Aggregation of Intravenous Immunoglobulin Induced by Mechanical Shock. Biotechnol J. 2020 Sep; 15(9):e2000096.
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Her C, Carpenter JF. Effects of Tubing Type, Formulation, and Postpumping Agitation on Nanoparticle and Microparticle Formation in Intravenous Immunoglobulin Solutions Processed With a Peristaltic Filling Pump. J Pharm Sci. 2020 01; 109(1):739-749.
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Ganesh AN, Aman A, Logie J, Barthel BL, Cogan P, Al-Awar R, Koch TH, Shoichet BK, Shoichet MS. Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence. ACS Chem Biol. 2019 04 19; 14(4):751-757.
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Gandhi AV, Randolph TW, Carpenter JF. Conjugation of Emtansine Onto Trastuzumab Promotes Aggregation of the Antibody-Drug Conjugate by Reducing Repulsive Electrostatic Interactions and Increasing Hydrophobic Interactions. J Pharm Sci. 2019 06; 108(6):1973-1983.
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Shah DD, Zhang J, Maity H, Mallela KMG. Effect of photo-degradation on the structure, stability, aggregation, and function of an IgG1 monoclonal antibody. Int J Pharm. 2018 Aug 25; 547(1-2):438-449.
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Qi W, Orgel S, Francon A, Randolph TW, Carpenter JF. Urea Improves Stability of Inactivated Polio Vaccine Serotype 3 During Lyophilization and Storage in Dried Formulations. J Pharm Sci. 2018 08; 107(8):2070-2078.
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Brar KK, Leung DYM. Eczema complicated by allergic contact dermatitis to topical medications and excipients. Ann Allergy Asthma Immunol. 2018 06; 120(6):599-602.
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Turner EA, Atigh MK, Erwin MM, Christians U, Yazdani SK. Coating and Pharmacokinetic Evaluation of Air Spray Coated Drug Coated Balloons. Cardiovasc Eng Technol. 2018 06; 9(2):240-250.
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Shaddy SM, Arnold MA, Shilo K, Frankel WL, Harzman AE, Stanich PP, Singhi AD, Yearsley MM, Arnold CA. Crospovidone and Microcrystalline Cellulose: A Novel Description of Pharmaceutical Fillers in the Gastrointestinal Tract. Am J Surg Pathol. 2017 Apr; 41(4):564-569.
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