 Excipients
"Excipients" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
| Descriptor ID |
D005079
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| MeSH Number(s) |
D26.650.700.419 D27.720.744.770.419
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Excipients".
Below are MeSH descriptors whose meaning is more specific than "Excipients".
This graph shows the total number of publications written about "Excipients" by people in this website by year, and whether "Excipients" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 2 | 1 | 3 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 4 | 5 | | 2002 | 0 | 1 | 1 | | 2005 | 0 | 5 | 5 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2008 | 2 | 2 | 4 | | 2009 | 1 | 3 | 4 | | 2010 | 1 | 3 | 4 | | 2012 | 1 | 1 | 2 | | 2013 | 1 | 2 | 3 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 4 | 0 | 4 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Excipients" by people in Profiles.
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Ganesh AN, Aman A, Logie J, Barthel BL, Cogan P, Al-Awar R, Koch TH, Shoichet BK, Shoichet MS. Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence. ACS Chem Biol. 2019 04 19; 14(4):751-757.
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Gandhi AV, Randolph TW, Carpenter JF. Conjugation of Emtansine Onto Trastuzumab Promotes Aggregation of the Antibody-Drug Conjugate by Reducing Repulsive Electrostatic Interactions and Increasing Hydrophobic Interactions. J Pharm Sci. 2019 06; 108(6):1973-1983.
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Shah DD, Zhang J, Maity H, Mallela KMG. Effect of photo-degradation on the structure, stability, aggregation, and function of an IgG1 monoclonal antibody. Int J Pharm. 2018 Aug 25; 547(1-2):438-449.
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Qi W, Orgel S, Francon A, Randolph TW, Carpenter JF. Urea Improves Stability of Inactivated Polio Vaccine Serotype 3 During Lyophilization and Storage in Dried Formulations. J Pharm Sci. 2018 08; 107(8):2070-2078.
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Brar KK, Leung DYM. Eczema complicated by allergic contact dermatitis to topical medications and excipients. Ann Allergy Asthma Immunol. 2018 06; 120(6):599-602.
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Turner EA, Atigh MK, Erwin MM, Christians U, Yazdani SK. Coating and Pharmacokinetic Evaluation of Air Spray Coated Drug Coated Balloons. Cardiovasc Eng Technol. 2018 06; 9(2):240-250.
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Shaddy SM, Arnold MA, Shilo K, Frankel WL, Harzman AE, Stanich PP, Singhi AD, Yearsley MM, Arnold CA. Crospovidone and Microcrystalline Cellulose: A Novel Description of Pharmaceutical Fillers in the Gastrointestinal Tract. Am J Surg Pathol. 2017 Apr; 41(4):564-569.
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Zhou C, Cleland D, Snell J, Qi W, Randolph TW, Carpenter JF. Formation of Stable Nanobubbles on Reconstituting Lyophilized Formulations Containing Trehalose. J Pharm Sci. 2016 07; 105(7):2249-53.
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Teska BM, Brake JM, Tronto GS, Carpenter JF. Aggregation and Particle Formation of Therapeutic Proteins in Contact With a Novel Fluoropolymer Surface Versus Siliconized Surfaces: Effects of Agitation in Vials and in Prefilled Syringes. J Pharm Sci. 2016 07; 105(7):2053-65.
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Christie M, Peritt D, Torres RM, Randolph TW, Carpenter JF. The Role of Protein Excipient in Driving Antibody Responses to Erythropoietin. J Pharm Sci. 2015 Dec; 104(12):4041-4055.
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